In this HOT article Xiu-Ping Yan and colleagues from Nankai University have developed a colourimetric method to determine the presence of histidine in urine. The method is detectable by the naked-eye, with an obvious colour change from yellow to purple. The detection of histidine, an amino acid found in many proteins, is used to help with the diagnosis of histidine metabolism disorders and other diseases such as epilepsy and Parkinson’s disease.
Yan et al., Analyst, 2012, Advance Article
Take a look at their paper, it will be free to read for 2 weeks.
An indicator-displacement assay for naked-eye detection and quantification of histidine in human urine
Shao-Kai Sun, Kai-Xiong Tu and Xiu-Ping Yan
Analyst, 2012, Advance Article
DOI: 10.1039/C2AN35126A
