Archive for the ‘Top 10’ Category

What are your colleagues reading in Organic & Biomolecular Chemistry?

The articles below are the most read Organic & Biomolecular Chemistry articles in July, August and September 2014.

Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling
Asmaa A. Sallam, Mohamed M. Mohyeldin, Ahmed I. Foudah, Mohamed R. Akl, Sami Nazzal, Sharon A. Meyer, Yong-Yu Liu and Khalid A. El Sayed 
DOI: 10.1039/C4OB00553H

Watsonianone A–C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana
Anthony R. Carroll, Vicky M. Avery, Sandra Duffy, Paul I. Forster and Gordon P. Guymer 
DOI: 10.1039/C2OB26931G

Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells
Sebastian Müller, Deborah A. Sanders, Marco Di Antonio, Stephanos Matsis, Jean-François Riou, Raphaël Rodriguez and Shankar Balasubramanian 
DOI: 10.1039/C2OB25830G

Synthesis, characterization and biological evaluation of carboranylmethylbenzo[b]acridones as novel agents for boron neutron capture therapy
A. Filipa F. da Silva, Raquel S. G. R. Seixas, Artur M. S. Silva, Joana Coimbra, Ana C. Fernandes, Joana P. Santos, António Matos, José Rino, Isabel Santos and Fernanda Marques 
DOI: 10.1039/C4OB00644E

Organic synthetic transformations using organic dyes as photoredox catalysts
Shunichi Fukuzumi and Kei Ohkubo 
DOI: 10.1039/C4OB00843J

Copper-catalysed direct radical alkenylation of alkyl bromides
Xu Zhang, Hong Yi, Zhixiong Liao, Guoting Zhang, Chao Fan, Chu Qin, Jie Liu and Aiwen Lei 
DOI: 10.1039/C4OB00813H

Metal-free oxidative olefination of primary amines with benzylic C–H bonds through direct deamination and C–H bond activation
Liang Gong, Li-Juan Xing, Tong Xu, Xue-Ping Zhu, Wen Zhou, Ning Kang and Bin Wang 
DOI: 10.1039/C4OB01025F

Recent advances in trifluoromethylation of organic compounds using Umemoto’s reagents
Cai Zhang 
DOI: 10.1039/C4OB00671B

An efficient route to synthesize isatins by metal-free, iodine-catalyzed sequential C(sp3)–H oxidation and intramolecular C–N bond formation of 2′-aminoacetophenones
Venkatachalam Rajeshkumar, Selvaraj Chandrasekar and Govindasamy Sekar 
DOI: 10.1039/C4OB01564A

Amino acid chirons: a tool for asymmetric synthesis of heterocycles
Priyanka Singh, Krishnananda Samanta, Sanjit Kumar Das and Gautam Panda 
DOI: 10.1039/C4OB00943F

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Q2 Top Ten most accessed articles

During the months April – June 2014, the most downloaded Organic & Biomolecualr Chemistry articles were:

Design, synthesis, and application of tartaric acid derived N-spiro quaternary ammonium salts as chiral phase-transfer catalysts
Mario Waser, Katharina Gratzer, Richard Herchl and Norbert Müller
DOI: 10.1039/C1OB06573D

Far-red and near infrared BODIPY dyes: synthesis and applications for fluorescent pH probes and bio-imaging
Yong Ni and Jishan Wu
DOI: 10.1039/C3OB42554A

Direct acylation of N-benzyltriflamides from the alcohol oxidation level via palladium-catalyzed C–H bond activation
Jihye Park, Aejin Kim, Satyasheel Sharma, Minyoung Kim, Eonjeong Park, Yukyoung Jeon, Youngil Lee, Jong Hwan Kwak, Young Hoon Jung and In Su Kim
DOI: 10.1039/C3OB40140E

sp3 C–H oxidation by remote H-radical shift with oxygen- and nitrogen-radicals: a recent update
Shunsuke Chiba and Hui Chen
DOI: 10.1039/C4OB00469H

Watsonianone A–C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana
Anthony R. Carroll, Vicky M. Avery, Sandra Duffy, Paul I. Forster and Gordon P. Guymer
DOI: 10.1039/C2OB26931G

Recent advances in biocompatible nanocarriers for delivery of chemotherapeutic cargoes towards cancer therapy
Chung Yen Ang, Si Yu Tan and Yanli Zhao
DOI: 10.1039/C4OB00164H

Continuous flow chemistry: a discovery tool for new chemical reactivity patterns
Jan Hartwig, Jan B. Metternich, Nikzad Nikbin, Andreas Kirschning and Steven V. Ley
DOI: 10.1039/C4OB00662C

Bifunctional primary amine-thioureas in asymmetric organocatalysis
Olga V. Serdyuk, Christina M. Heckel and Svetlana B. Tsogoeva
DOI: 10.1039/C3OB41403E

Palladium-catalyzed three-component reaction of N-tosylhydrazone, norbornene and aryl halide
Fangdong Hu, Ying Xia, Zhenxing Liu, Chen Ma, Yan Zhang and Jianbo Wang
DOI: 10.1039/C4OB00590B

A coumarin-quinolinium-based fluorescent probe for ratiometric sensing of sulfite in living cells
Li Tan, Weiying Lin, Sasa Zhu, Lin Yuan and Kaibo Zheng
DOI: 10.1039/C4OB00132J

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Q1 Top Ten most accessed Organic & Biomolecular Chemistry articles

During January, February and March this year, the following articles were the Top Ten most accessed:

Rapid synthesis of Abelson tyrosine kinase inhibitors using click chemistry
Karunakaran A. Kalesh, Kai Liu and Shao Q. Yao  
Org. Biomol. Chem., 2009,7, 5129-5136
DOI: 10.1039/b913333j

Bifunctional primary amine-thioureas in asymmetric organocatalysis
Olga V. Serdyuk, Christina M. Heckel and Svetlana B. Tsogoeva  
Org. Biomol. Chem., 2013,11, 7051-7071
DOI: 10.1039/c3ob41403e

Copper-catalyzed highly efficient ester formation from carboxylic acids/esters and formates
Jun Liu, Changdong Shao, Yanghui Zhang, Guangfa Shi and Shulei Pan
Org. Biomol. Chem., 2014,12, 2637-2640
DOI: 10.1039/c4ob00193a

Synthetic applications of photoredox catalysis with visible light
Yumeng Xi, Hong Yi and Aiwen Lei  
Org. Biomol. Chem., 2013,11, 2387-2403
DOI: 10.1039/c3ob40137e

Recent progress towards transition metal-catalyzed synthesis of y-lactams
Long-Wu Ye, Chao Shu and Fabien Gagosz  
Org. Biomol. Chem., 2014,12, 1833-1845
DOI: 10.1039/c3ob42181c

Synthesis of substituted pyrenes by indirect methods
Juan M. Casas-Solvas, Joshua D. Howgego and Anthony P. Davis
Org. Biomol. Chem., 2014,12, 212-232
DOI: 10.1039/c3ob41993b

KI-catalyzed arylation of benzothiazoles from the coupling of aryl aldehydes with benzothiazoles in neat water
Yuyu Gao, Qiuling Song, Guolin Cheng and Xiuling Cui  
Org. Biomol. Chem., 2014,12, 1044-1047
DOI: 10.1039/c3ob42318b

A biocompatible, highly efficient click reaction and its applications
Yue Yuan and Gaolin Liang  
Org. Biomol. Chem., 2014,12, 865-871
DOI: 10.1039/c3ob41241e

“Frustrated Lewis pairs”: a concept for new reactivity and catalysis
Douglas W. Stephan  
Org. Biomol. Chem., 2008,6, 1535-1539
DOI: 10.1039/b802575b

Support of academic synthetic chemistry using separation technologies from the pharmaceutical industry
Erik L. Regalado, Marisa C. Kozlowski, John M. Curto, Tobias Ritter, Michael G. Campbell, Anthony R. Mazzotti, Bruce C. Hamper, Christopher D. Spilling, Michael P. Mannino, Li Wan, Jin-Quan Yu, Jinchu Liu and Christopher J. Welch  
Org. Biomol. Chem., 2014,12, 2161-2166
DOI: 10.1039/c3ob42195c

Please post your comments or thoughts on any of these articles in the comment box below.

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Q4 Top Ten most accessed Organic & Biomolecular Chemistry articles

During October, November and December, the following articles were the Top Ten most accessed:

A coumarin-based fluorescent probe for biological thiols and its application for living cell imaging
Lingliang Long, Liping Zhou, Lin Wang, Suci Meng, Aihua Gong, Fengyi Du and Chi Zhang
Org. Biomol. Chem., 2013,11, 8214-8220
DOI: 10.1039/c3ob41741g; Download PDF

Bifunctional primary amine-thioureas in asymmetric organocatalysis
Olga V. Serdyuk, Christina M. Heckel and Svetlana B. Tsogoeva
Org. Biomol. Chem., 2013,11, 7051-7071
DOI: 10.1039/c3ob41403e; Download PDF

To be or not to be metal-free: trends and advances in coupling chemistries
Rick Arneil D. Arancon, Carol Sze Ki Lin, Carolina Vargas and Rafael Luque
Org. Biomol. Chem., 2014,12, 10-35
DOI: 10.1039/c3ob41768a; Download PDF

Synthetic applications of arylboronic acid via an aryl radical transfer pathway
Guobing Yan, Minghua Yang and Xiangmei Wu
Org. Biomol. Chem., 2013,11, 7999-8008
DOI: 10.1039/c3ob41851k; Download PDF

Synthetic applications of photoredox catalysis with visible light
Yumeng Xi, Hong Yi and Aiwen Lei
Org. Biomol. Chem., 2013,11, 2387-2403
DOI: 10.1039/c3ob40137e; Download PDF

Analysis of the reactions used for the preparation of drug candidate molecules
John S. Carey, David Laffan, Colin Thomson and Mike T. Williams
Org. Biomol. Chem., 2006,4, 2337-2347
DOI: 10.1039/b602413k; Download PDF

N-heterocyclic carbene-catalyzed reactions of C–C unsaturated bonds
Xiang-Yu Chen and Song Ye
Org. Biomol. Chem., 2013,11, 7991-7998
DOI: 10.1039/c3ob41469h; Download PDF

Copper-catalyzed redox-neutral C–H amination with amidoximes
Hui Chen and Shunsuke Chiba
Org. Biomol. Chem., 2014,12, 42-46
DOI: 10.1039/c3ob41871e; Download PDF

Recent trends in Pd-catalyzed remote functionalization of carbonyl compounds
Ivan Franzoni and Clément Mazet
Org. Biomol. Chem., 2014,12, 233-241
DOI: 10.1039/c3ob42050g; Download PDF

Maximising multivalency effects in protein–carbohydrate interactions
Roland J. Pieters
Org. Biomol. Chem., 2009,7, 2013-2025
DOI: 10.1039/b901828j; Download PDF

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Q3 Top Ten most accessed Organic & Biomolecular Chemistry articles

During July, August and September, the following articles were the Top Ten most accessed:

Synthesis of azetidines and pyrrolidines via iodocyclisation of homoallyl amines and exploration of activity in a zebrafish embryo assay
Antonio Feula, Sundeep S. Dhillon, Rama Byravan, Mandeep Sangha, Ronald Ebanks, Mariwan A. Hama Salih, Neil Spencer, Louise Male, Istvan Magyary, Wei-Ping Deng, Ferenc Müller and John S. Fossey
Org. Biomol. Chem., 2013, 11, 5083-5093
DOI: 10.1039/c3ob41007b

Electrophilicity: the “dark-side” of indole chemistry
Marco Bandini
Org. Biomol. Chem., 2013, 11, 5206-5212
DOI: 10.1039/c3ob40735g

Transition-metal-catalyzed additions of C–H bonds to C–X (X = N, O) multiple bonds via C–H bond activation
Guobing Yan, Xiangmei Wu and Minghua Yang
Org. Biomol. Chem., 2013, 11, 5558-5578
DOI: 10.1039/c3ob40652k

Synthetic applications of photoredox catalysis with visible light
Yumeng Xi, Hong Yi and Aiwen Lei  
Org. Biomol. Chem., 2013,11, 2387-2403
DOI: 10.1039/C3OB40137E

Bioorthogonal labelling of biomolecules: new functional handles and ligation methods
Marjoke F. Debets, Jan C. M. van Hest and Floris P. J. T. Rutjes  
Org. Biomol. Chem., 2013,11, 6439-6455
DOI: 10.1039/C3OB41329B

DABCO-promoted synthesis of pyrazoles from tosylhydrazones and nitroalkenes
Meng Tang, Wen Zhang and Yuanfang Kong  
Org. Biomol. Chem., 2013,11, 6250-6254
DOI: 10.1039/C3OB41435C

Organocatalytic asymmetric synthesis of ß3-amino acid derivatives
Sun Min Kim and Jung Woon Yang
Org. Biomol. Chem., 2013, 11, 4737-4749
DOI: 10.1039/c3ob40917a

The first asymmetric total synthesis of (+)-coriandrone A and B
Wenjing Wang, Jijun Xue, Tian Tian, Yingdong Jiao and Ying Li  
Org. Biomol. Chem., 2013,11, 6686-6690
DOI: 10.1039/C3OB41497C

Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma
Kai Liu, Datong Zhang, Jeremy Chojnacki, Yuhong Du, Haian Fu, Steven Grant and Shijun Zhang  
Org. Biomol. Chem., 2013,11, 4757-4763
DOI: 10.1039/C3OB40595H

Pd(0)-catalyzed benzylic arylation–oxidation of 4-methylquinazolines via sp3 C–H activation under air conditions
Dan Zhao, Min-Xue Zhu, Yue Wang, Qi Shen and Jian-Xin Li  
Org. Biomol. Chem., 2013,11, 6246-6249
DOI: 10.1039/C3OB41488D

If you have any thoughts or comments on any of these articles, please post these below.

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Q2 Top 10 for Organic & Biomolecular Chemistry

Please take a look at the top 10 most accessed Organic & Biomolecular Chemistry articles for the second quarter of 2013:

Synthetic applications of photoredox catalysis with visible light  
Yumeng Xi, Hong Yi and Aiwen Lei  
Org. Biomol. Chem., 2013, 11, 2387-2403  
DOI: 10.1039/C3OB40137E 

Redesign of enzyme for improving catalytic activity and enantioselectivity toward poor substrates: manipulation of the transition state  
Tadashi Ema, Yasuko Nakano, Daiki Yoshida, Shusuke Kamata and Takashi Sakai  
Org. Biomol. Chem., 2012, 10, 6299-6308  
DOI: 10.1039/C2OB25614B 

Recent advances in the synthesis of aromatic nitro compounds  
Guobing Yan and Minghua Yang  
Org. Biomol. Chem., 2013, 11, 2554-2566  
DOI: 10.1039/C3OB27354G 

Expeditious synthesis of bacterial, rare sugar building blocks to access the prokaryotic glycome  
Madhu Emmadi and Suvarn S. Kulkarni  
Org. Biomol. Chem., 2013, 11, 3098-3102  
DOI: 10.1039/C3OB40615F 

Transition metal-catalyzed functionalization of pyrazines  
Nicolai I. Nikishkin, Jurriaan Huskens and Willem Verboom   
Org. Biomol. Chem., 2013, 11, 3583-3602  
DOI: 10.1039/C3OB40460A 

New trends in bismuth-catalyzed synthetic transformations  
Thierry Ollevier 
Org. Biomol. Chem., 2013, 11, 2740-2755  
DOI: 10.1039/C3OB26537D 

Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents  
Kyriacos C. Nicolaou and Roman A. Valiulin 
Org. Biomol. Chem., 2013, 11, 4154-4163  
DOI: 10.1039/C3OB40654G 

Manipulating non-innocent π-spacers: the challenges of using 2,6-disubstituted BODIPY cores within donor–acceptor light-harvesting motifs  
Catherine Bonnier, Devin D. Machin, Omar Abdi and Bryan D. Koivisto 
Org. Biomol. Chem., 2013, 11, 3756-3760  
DOI: 10.1039/C3OB40213D 

Bu4NI-catalyzed decarboxylative acyloxylation of an sp3 C–H bond adjacent to a heteroatom with α-oxocarboxylic acids  
Shuai Zhang, Li-Na Guo, Hua Wang and Xin-Hua Duan 
Org. Biomol. Chem., 2013, 11, 4308-4311  
DOI: 10.1039/C3OB40748A 

Recent applications of arene diazonium salts in organic synthesis  
Fanyang Mo, Guangbin Dong, Yan Zhang and Jianbo Wang 
Org. Biomol. Chem., 2013, 11, 1582-1593  
DOI: 10.1039/C3OB27366K

We would very much welcome your thoughts and comments below.

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OBC Top 10 most accessed articles published in 2012 (Volume 10)

Curious about which articles published in 2012 gathered most readership? Here are the Top 10 works your colleagues have been accessing in Organic & Biomolecular Chemistry:

A one-pot catalysis: the strategic classification with some recent examples
Nitin T. Patil, Valmik S. Shinde and Balakrishna Gajula
Org. Biomol. Chem., 2012, 10, 211-224
DOI: 10.1039/C1OB06432K

A convenient and mild chromatography-free method for the purification of the products of Wittig and Appel reactions
Peter A. Byrne, Kamalraj V. Rajendran, Jimmy Muldoon and Declan G. Gilheany
Org. Biomol. Chem., 2012, 10, 3531-3537
DOI: 10.1039/C2OB07074J

Imidazole derivatives: A comprehensive survey of their recognition properties
Pedro Molina, Alberto Tárraga and Francisco Otón
Org. Biomol. Chem., 2012, 10, 1711-1724
DOI: 10.1039/C2OB06808G

Enhanced reduction of C–N multiple bonds using sodium borohydride and an amorphous nickel catalyst
Shouxin Liu, Yihua Yang, Xiaoli Zhen, Junzhang Li, Huimin He, Juan Feng and Andrew Whiting
Org. Biomol. Chem., 2012, 10, 663-670
DOI: 10.1039/C1OB06471A

Strategies for the enantioselective synthesis of spirooxindoles
Nicolas R. Ball-Jones, Joseph J. Badillo and Annaliese K. Franz
Org. Biomol. Chem., 2012, 10, 5165-5181
DOI: 10.1039/C2OB25184A

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications
Alessandro Massi and Daniele Nanni
Org. Biomol. Chem., 2012, 10, 3791-3807
DOI: 10.1039/C2OB25217A

Small molecule control of bacterial biofilms
Roberta J. Worthington, Justin J. Richards and Christian Melander
Org. Biomol. Chem., 2012, 10, 7457-7474
DOI: 10.1039/C2OB25835H

Asymmetric organocatalytic formation of protected and unprotected tetroses under potentially prebiotic conditions
Laurence Burroughs, Paul A. Clarke, Henrietta Forintos, James A. R. Gilks, Christopher J. Hayes, Matthew E. Vale, William Wade and Myriam Zbytniewski
Org. Biomol. Chem., 2012, 10, 1565-1570
DOI: 10.1039/C1OB06798B

Olefin cross-metathesis for the synthesis of heteroaromatic compounds
Timothy J. Donohoe, John F. Bower and Louis K. M. Chan
Org. Biomol. Chem., 2012, 10, 1322-1328
DOI: 10.1039/C2OB06659A

Selective N-alkylation of amines using nitriles under hydrogenation conditions: facile synthesis of secondary and tertiary amines
Takashi Ikawa, Yuki Fujita, Tomoteru Mizusaki, Sae Betsuin, Haruki Takamatsu, Tomohiro Maegawa, Yasunari Monguchi and Hironao Sajiki
Org. Biomol. Chem., 2012, 10, 293-304
DOI: 10.1039/C1OB06303K

Interested in submitting your own work to OBC? Submit online today, or email us with your suggestions!

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Top ten most accessed articles in July 2012

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Recent progress of core-substituted naphthalenediimides: highlights from 2010  
Sheshanath V. Bhosale, Sidhanath V. Bhosale and Suresh K. Bhargava  
Org. Biomol. Chem., 2012, 10, 6455-6468
DOI: 10.1039/C2OB25798J

A new N-imidazolyl-1,8-naphthalimide based fluorescence sensor for fluoride detection  
Junqi Wang, Lingyun Yang, Chen Hou and Haishi Cao  
Org. Biomol. Chem., 2012, 10, 6271-6274
DOI: 10.1039/C2OB25903F

Asymmetric organocatalytic diboration of alkenes  
Amadeu Bonet, Cristina Sole, Henrik Gulyás and Elena Fernández  
Org. Biomol. Chem., 2012, 10, 6621-6623
DOI: 10.1039/C2OB26079D

Transition metal-catalyzed fluorination of multi carbon–carbon bonds: new strategies for fluorinated heterocycles 
Guosheng Liu  
Org. Biomol. Chem., 2012, 10, 6243-6248
DOI: 10.1039/C2OB25702E

π-Fused bis-BODIPY as a candidate for NIR dyes  
Mitsunori Nakamura, Hiroyuki Tahara, Kohtaro Takahashi, Toshi Nagata, Hiroki Uoyama, Daiki Kuzuhara, Shigeki Mori, Tetsuo Okujima, Hiroko Yamada and Hidemitsu Uno  
Org. Biomol. Chem., 2012, 10, 6840-6849
DOI: 10.1039/C2OB25930C
 
Enantio- and diastereocontrolled conversion of chiral epoxides to trans-cyclopropane carboxylates: application to the synthesis of cascarillic acid, grenadamide and L-(−)-CCG-II  
Pradeep Kumar, Abhishek Dubey and Anand Harbindu  
Org. Biomol. Chem., 2012, 10, 6987-6994
DOI: 10.1039/C2OB25622C  
 
From biomass to medicines. A simple synthesis of indolo[3,2-c]quinolines, antimalarial alkaloid isocryptolepine, and its derivatives 
Maxim G. Uchuskin, Arkady S. Pilipenko, Olga V. Serdyuk, Igor V. Trushkov and Alexander V. Butin  
Org. Biomol. Chem., 2012, 10, 7262-7265
DOI: 10.1039/C2OB25836F  

Chiral phosphine-catalyzed asymmetric allylic alkylation of 3-substituted benzofuran-2(3H)-ones or oxindoles with Morita–Baylis–Hillman carbonates  
De Wang, Yuan-Liang Yang, Jia-Jun Jiang and Min Shi  
Org. Biomol. Chem., 2012, 10, 7158-7166
DOI: 10.1039/C2OB25694K  
 
Diverted organic synthesis (DOS): accessing a new, natural product inspired, neurotrophically active scaffold through an intramolecular Pauson–Khand reaction  
Goverdhan Mehta, Ramesh Samineni, Pabbaraja Srihari, R. Gajendra Reddy and Sumana Chakravarty  
Org. Biomol. Chem., 2012, 10, 6830-6833
DOI: 10.1039/C2OB26107C  
 
Asymmetric synthesis of (+)-vertine and (+)-lythrine 
Laëtitia Chausset-Boissarie, Roman Àrvai, Graham R. Cumming, Laure Guénée and E. Peter Kündig 
Org. Biomol. Chem., 2012, 10, 6473-6479
DOI: 10.1039/C2OB25880C  

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.

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Top ten most accessed articles in June

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

Efficient iodine catalyzed three components domino reaction for the synthesis of 1-((phenylthio)(phenyl)methyl)pyrrolidin-2-one derivatives possessing anticancer activities
Gunasekar Ramachandran, Natesan S. Karthikeyan, Periyasamy Giridharan and Kulathu I. Sathiyanarayanan
Org. Biomol. Chem., 2012, 10, 5343-5346
DOI: 10.1039/C2OB25530H

A BODIPY-based colorimetric and fluorometric chemosensor for Hg(II) ions and its application to living cell imaging
Mani Vedamalai and Shu-Pao Wu
Org. Biomol. Chem., 2012, 10, 5410-5416
DOI: 10.1039/C2OB25589H

Copper-catalyzed domino coupling reaction: an efficient method to synthesize oxindoles
Jen-Chieh Hsieh, An-Yi Cheng, Jun-Hao Fu and Ting-Wei Kang
Org. Biomol. Chem., 2012, 10, 6404-6409
DOI: 10.1039/C2OB26110C

Asymmetric formal synthesis of schulzeines A and C
Jaebong Jang, Jong-Wha Jung, Jaeseung Ahn, Jaehoon Sim, Dong-Jo Chang, Dae-Duk Kim and Young-Ger Suh
Org. Biomol. Chem., 2012, 10, 5202-5204
DOI: 10.1039/C2OB25772F

Chiral quaternary phosphonium salts: a new class of organocatalysts
Dieter Enders and Thanh Vinh Nguyen
Org. Biomol. Chem., 2012, 10, 5327-5331
DOI: 10.1039/C2OB25823D

Total synthesis of indole-3-acetonitrile-4-methoxy-2-C-β-D-glucopyranoside. Proposal for structural revision of the natural product
Akop Yepremyan and Thomas G. Minehan
Org. Biomol. Chem., 2012, 10, 5194-5196
DOI: 10.1039/C2OB25821H

Enantioselective synthesis of 3,3′-dihydropyrryl-spirooxindoles via an organocatalytic three-component reaction
Wen-Tao Wei, Chun-Xia Chen, Rui-Jiong Lu, Jin-Jia Wang, Xue-Jing Zhang and Ming Yan
Org. Biomol. Chem., 2012, 10, 5245-5252
DOI: 10.1039/C2OB25629K

A convergent stereocontrolled total synthesis of (–)-terpestacin
Yehua Jin and Fayang G. Qiu
Org. Biomol. Chem., 2012, 10, 5452-5455
DOI: 10.1039/C2OB25940K

A cyanine based fluorophore emitting both single photon near-infrared fluorescence and two-photon deep red fluorescence in aqueous solution
Lu Wang, Jiefu Jin, Xishan Chen, Hai-Hua Fan, Billy King Fai Li, Kok-Wai Cheah, Ning Ding, Shenghong Ju, Wing-Tak Wong and Cong Li
Org. Biomol. Chem., 2012, 10, 5366-5370
DOI: 10.1039/C2OB25619C

Transition metal-catalyzed fluorination of multi carbon–carbon bonds: new strategies for fluorinated heterocycles
Guosheng Liu
Org. Biomol. Chem., 2012, 10, 6243-6248
DOI: 10.1039/C2OB25702E

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Top ten most accessed articles in May

This month sees the following articles in Organic & Biomolecular Chemistry that are in the top ten most accessed:

PTSA-catalyzed Mannich-type–cyclization–oxidation tandem reactions: one-pot synthesis of 1,3,5-substituted pyrazoles from aldehydes, hydrazines and alkynes
Pei Liu, Ying-Ming Pan, Yan-Li Xu and Heng-Shan Wang
Org. Biomol. Chem., 2012, 10, 4696-4698
DOI: 10.1039/C2OB25487E

A new ratiometric and colorimetric chemosensor for cyanide anion based on Coumarin–hemicyanine hybrid
Zhenghao Yang, Zhipeng Liu, Yuncong Chen, Xiaoqing Wang, Weijiang He and Yi Lu
Org. Biomol. Chem., 2012, 10, 5073-5076
DOI: 10.1039/C2OB25516B

Highly enantioselective Biginelli reaction catalyzed by SPINOL-phosphoric acids
Fangxi Xu, Dan Huang, Xufeng Lin and Yanguang Wang
Org. Biomol. Chem., 2012, 10, 4467-4470
DOI: 10.1039/C2OB25663K

One-pot synthesis of 1,2,3-triazoles from boronic acids in water using Cu(II)–ß-cyclodextrin complex as a nanocatalyst
Babak Kaboudin, Yaghoub Abedi and Tsutomu Yokomatsu
Org. Biomol. Chem., 2012, 10, 4543-4548
DOI: 10.1039/C2OB25061F

The ligand and base-free Pd-catalyzed oxidative Heck reaction of arylboronic acids and olefins
Peng Sun, Yan Zhu, Hailong Yang, Hong Yan, Linhua Lu, Xiang Zhang and Jincheng Mao
Org. Biomol. Chem., 2012, 10, 4512-4515
DOI: 10.1039/C2OB25462J

Very high stereoselectivity in organocatalyzed desymmetrizing aldol reactions of 3-substituted cyclobutanones
David J. Aitken, Angela M. Bernard, Francesca Capitta, Angelo Frongia, Régis Guillot, Jean Ollivier, Pier Paolo Piras, Francesco Secci and Marco Spiga
Org. Biomol. Chem., 2012, 10, 5045-5048
DOI: 10.1039/C2OB25813G

First total synthesis of (+)-indicanone
Yujiro Hayashi, Kumiko Ogawa, Fuyuhiko Inagaki and Chisato Mukai
Org. Biomol. Chem., 2012, 10, 4747-4751
DOI: 10.1039/C2OB25500F

Strategy for catch and release of azide-tagged biomolecules utilizing a photolabile strained alkyne construct
Martin Golkowski, Carlo Pergola, Oliver Werz and Thomas Ziegler
Org. Biomol. Chem., 2012, 10, 4496-4499
DOI: 10.1039/C2OB25440A

Synthesis of diversely 1,3,5-trisubstituted pyrazoles via 5-exo-dig cyclization
Dmitry A. Borkin, Mirela Puscau, Alena Carlson, Agnes Solan, Kraig A. Wheeler, Béla Török and Roman Dembinski
Org. Biomol. Chem., 2012, 10, 4505-4508
DOI: 10.1039/C2OB25580D

Thiol–yne coupling: revisiting old concepts as a breakthrough for up-to-date applications
Alessandro Massi and Daniele Nanni
Org. Biomol. Chem., 2012, 10, 3791-3807
DOI: 10.1039/C2OB25217A

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to Organic & Biomolecular Chemistry? Then why not submit to us today or alternatively email us your suggestions.

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