Archive for November, 2015

Natural Products in OBC – our latest selection

Organic & Biomolecular Chemistry, our sister journal, publishes many articles that cover a variety of natural product chemistry.

We try to keep you updated here, although signing up to OBC’s e-alert (free service) means you will receive the tables of content directly in your inbox every time an issue is published.

Hand-picked for you from the latest issues are:

Total synthesis and absolute stereochemistry of the proteasome inhibitors cystargolides A and B
Rodolfo Tello-Aburto, Liam P. Hallada, Doleshwar Niroula and Snezna Rogelj
DOI: 10.1039/C5OB01821H, Communication


Investigations into the binding of jadomycin DS to human topoisomerase IIβ by WaterLOGSY NMR spectroscopy
Camilo F. Martinez-Farina, Nicole McCormick, Andrew W. Robertson, Helen Clement, Alison Jee, Anna Ampaw, Nei-Li Chan, Ray T. Syvitski and David L. Jakeman
DOI: 10.1039/C5OB01508A, Paper


The energetic viability of an unexpected skeletal rearrangement in cyclooctatin biosynthesis
Young J. Hong and Dean J. Tantillo
DOI: 10.1039/C5OB01785H, Communication
From themed collection 2015 Hot Articles in Organic and Biomolecular Chemistry


Synthetic studies on the bioactive tetramic acid JBIR-22 using a late stage Diels–Alder reaction
A. R. Healy and N. J. Westwood
DOI: 10.1039/C5OB01771H, Paper


The first total synthesis of (+)-goniothalesacetate and syntheses of (+)-altholactone, (+)-gonioheptolide A, and (−)-goniofupyrone by an asymmetric acetate aldol approach
Sandeep AnkiReddy, Praveen AnkiReddy and Gowravaram Sabitha
DOI: 10.1039/C5OB01598G, Paper


4π electrocyclisation in domino processes: contemporary trends and synthetic applications towards natural products
Nadeem S. Sheikh
DOI: 10.1039/C5OB01703C, Review Article


Total synthesis of calothrixin B via sequential Sonogashira coupling/copper-catalyzed oxidative cyclization
Nagarajan Ramkumar and Rajagopal Nagarajan
DOI: 10.1039/C5OB01766A, Paper


Practical isolation of polygodial from Tasmannia lanceolata: a viable scaffold for synthesis
Jeremy Just, Timothy B. Jordan, Brett Paull, Alex C. Bissember and Jason A. Smith
DOI: 10.1039/C5OB01573A, Paper


Chemoenzymatic collective synthesis of optically active hydroxyl(methyl)tetrahydronaphthalene-based bioactive terpenoids
Ramesh U. Batwal and Narshinha P. Argade
DOI: 10.1039/C5OB01740H, Paper


We hope you enjoy this selection!
Why not submit your latest natural product research to OBC today?

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Ryan Shenvi wins 2016 NPR Emerging Investigator Lectureship

NPR Emerging Investigator Lectureship 2016We are delighted to announce that Professor Ryan Shenvi from the Scripps Research Institute in San Diego (USA) is the winner of the 2016 NPR Emerging Investigator Lectureship.

The NPR Lectureship is an annual event which is held at an international meeting, the recipient being a researcher who has made a significant contribution to any natural products-related research in their early independent career.

The conference at which the lecture will be delivered will be announced in due course.

Read more on Ryan’s research on the Shenvi lab homepage.

Previous winners include:

Seth Herzon, Yale University, USA (2015 winner)
Emily Balskus, Harvard University, USA (2014 winner)
Rebecca Goss, University of St Andrews, UK (2013 winner)
Dean Tantillo, UC Davis Chemistry, USA (2012 winner)

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What are your colleagues reading in Natural Product Reports?

The articles below are the most read Natural Product Reports articles in July, August and September 2015.

Natural product isolation – how to get from biological material to pure compounds
Franz Bucar, Abraham Wube and Martin Schmid
DOI: 10.1039/C3NP20106F, Review Article

Natural products and Pharma 2011: Strategic changes spur new opportunities
Guy T. Carter
DOI: 10.1039/C1NP00033K, Highlight

Marine natural products
John W. Blunt, Brent R. Copp, Robert A. Keyzers, Murray H. G. Munro and Michèle R. Prinsep
DOI: 10.1039/C4NP00144C, Review Article

Defensive symbioses of animals with prokaryotic and eukaryotic microorganisms
Laura V. Flórez, Peter H. W. Biedermann, Tobias Engl and Martin Kaltenpoth
DOI: 10.1039/C5NP00010F, Review Article

Metabolomics in chemical ecology
Constanze Kuhlisch and Georg Pohnert
DOI: 10.1039/C5NP00003C, Review Article

Hot off the press
Robert A. Hill and Andrew Sutherland
DOI: 10.1039/C5NP90032H, Hot off the Press Article

Natural product and natural product derived drugs in clinical trials
Mark S. Butler, Avril A. B. Robertson and Matthew A. Cooper
DOI: 10.1039/C4NP00064A, Review Article

Mass spectrometry imaging of plant metabolites – principles and possibilities
Nanna Bjarnholt, Bin Li, Janina D’Alvise and Christian Janfelt
DOI: 10.1039/C3NP70100J, Review Article

Triterpenoids
Robert A. Hill and Joseph D. Connolly
DOI: 10.1039/C4NP00101J, Review Article

The chemistry and biological activity of the Hyacinthaceae
Dulcie A. Mulholland, Sianne L. Schwikkard and Neil R. Crouch
DOI: 10.1039/C3NP70008A, Review Article

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