Archive for September, 2013

Profiles of the 18th ESOC Bursary Awardees

NJC, committed to supporting the younger members of the chemistry community, underwrote student bursaries at this summer’s 18th European Symposium on Organic Chemistry, held in Marseille this past July. The 8 young awardees, from 8 European countries, are briefly profiled here.

Szilvia Deak is a second year Ph.D. student in the research group of Prof. Ferenc Faigl at Budapest University of Technology and Economics, Department of Organic Chemistry and Technology (Hungary). The group develops novel regio- and stereoselective metallation processes for the synthesis of atropisomeric functionalised biaryls (1-phenylpyrrole derivatives) and optically active heterocyclic compounds (oxiranes, oxetanes, pyrrolidines) as potential chiral ligands and organocatalysts.
Szilvia’s poster was entitled “Atropisomeric amino alcohols as new chiral ligands in asymmetric synthesis”.

Paulina Hamankiewicz is currently finishing her Ph.D. thesis on molecular and chiral recognition of organic compounds using carbohydrate derivatives, decorated with urea moieties. She will be graduating from the University of Warsaw (Poland), where she is in the group of Prof. Janusz Jurczak (Laboratory of Stereocontrolled Organic Synthesis).
Paulina’s poster: “Benzene, naphthalene, and anthracene urea derivatives as convenient tools for chiral recognition”.

Maria Riala is from the Department of Chemistry of the University of Cyprus in Nicosia (Cyprus). After her undergraduate degree she completed her Ph.D. studies in the Research Laboratory of Fullerene and Supramolecular Chemistry under the supervision of Asst. Prof. Nikos Chronakis and graduated in June 2013. Maria’s research is focused on the synthesis of bis- and trisadducts of C60 with an inherently chiral addition pattern utilizing enantiomerically pure tethers.
Maria’s poster: “Synthesis of chiral Th-symmetrical hexakis adducts of C60.

Ekrem Kaplan is a Masters chemistry student at Istanbul Technical University (Turkey). Under the supervisor of Prof. Esin Hamuryudan, Ekrem is preparing peripheral and non-peripheral substituted manganese(III) phthalocyanine bearing carboxylic side groups and investigating their electrochemical properties.
Ekrem’s poster: “Synthesis and Electrochemical Studies of Carboxylic Acid Functionalized Phthalocyanines”.

Tatiana Dias is a Ph.D. student in the Chemistry Research Centre at the University of Minho (Portugal) in the group of Prof. Fernanda Proença. The research group’s work is focused on the synthesis of new drug candidates, mainly nitrogen and oxygen-containing heterocyclic structures. Tatiana’s research has been centred on the development of new synthetic methodologies to prepare chromene derivatives to be tested as anticancer agents.
Tatiana’s poster at ESOC was “2-Hydroxychalcones and carbon acid derivatives: Reactivity studies in acid media”.

Kostas Voreakos is writing up his Master’s dissertation, after completing his research in the group of Dr. Dimitris Georgiadis of the Laboratory of Organic Chemistry, Department of Chemistry in the National and Kapodistrian University of Athens (Greece). The research group focuses on the design and synthesis of metallopeptidase inhibitors and the development of synthetic methodologies for medicinal applications. Previously, Kostas earned first degrees in both chemistry and food technology.
Kostas’s poster at ESOC was entitled “Conformationally Constrained Phosphinic Peptides: Synthesis of α,β-Disubstituted Phosphinyl Propanoates and Development of δ-lactam Phosphinic Surrogates”.
Phosphinic Peptides
Agnese Stikute is a 4th year undergraduate student in Chemical Engineering at the Faculty of Material Science and Applied Chemistry of Riga Technical University (Latvia). She works in the Institute of Technology of Organic Chemistry/Department of Chemical Technology of Biologically Active Compounds under the supervision of Prof. Mara Jure. Agnese’s research is devoted to the synthesis of analogues of natural antioxidants, focused on the discovery and optimization of the synthesis of cinnamoyl anilines and their derivatives.
Agnese’s poster: “Cyclization of monoanilides of arylidene malonic acid”.

Kärt Reitel is a Ph.D. student in Tallinn University of Technology (Estonia). She works in the organic synthesis group under the supervision of Prof. Tõnis Kanger. Kärt’s main research topic is the synthesis of cyclopropane-containing compounds and their application in organocatalytic reactions.
Kärt’s ESOC poster was entitled “Aminocatalytic Michael addition of cyclopropane-containing aldehydes to nitroolefins”.

Congratulations to all the awardees! (Check out “who is who” in the photo montage below.)

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Meet Our Authors – September 2013 issue of NJC

Let’s meet the people behind the papers! This month, two authors kindly took some time to answer a few questions for us.

Our first author is Yasuhiro Shiraishi who is Associate Professor at the Research Center for Solar Energy Chemistry of Osaka University (Japan). Yasuhiro’s research interests are focused on the design of photocatalysts for selective organic transformations and fluorescent molecular devices driven by light.

The article by Yasuhiro and his co-authors reports the synthesis of a spiropyran-cholesterol that undergoes reversible color and phase transitions upon heat and light stimuli. These properties were successfully applied to the creation of a material for information storage, easily writable and erasable by simple light irradiation.

The interdisciplinary nature of the work, involving polymer chemistry and photochemistry made NJC a logical choice in the authors’ eyes.

Besides being a research scientist, Yasuhiro’s dream job would be professional footballer. And not surprisingly, his primary focus outside of the lab is to raise his two boys to be as good footballers as Leo Messi.

“Spiropyran–cholesterol conjugate as a photoresponsive organogelator” Shigehiro Sumiya, Yasuhiro Shiraishi and Takayuki Hirai New J. Chem., 2013, 37, 2642-2647. DOI: 10.1039/C3NJ00322A

Antonio Frontera is Full Professor of Organic Chemistry in the Department of Chemistry at the Universitat de les Illes Balears (Spain). His research is in the field of Theoretical Chemistry, with an emphasis on the study of non covalent interactions.

About his paper, Antonio commented: “Seventeen years ago, pi-facial interactions were described by John D. Woolins and coworkers in thiotrithiazylium salts. Their pioneering work can be considered as the birth of the nowadays well recognized anion–pi interaction and the research published in our manuscript on this topic is dedicated to them.”

The authors chose NJC to publish this research work because the journal is addressed to a cross-disciplinary and wide readership.

Playing basketball in wintertime and fishing in summertime are Antonio’s favorite activities besides chemistry (see the photo: nice catch!). If he could not be a scientific investigator, Antonio would be a private investigator.

“Anion–π interactions in [S4N3]+ rings” Antonio Bauzá, David Quiñonero, Pere M. Deyà and Antonio Frontera New J. Chem., 2013, 37, 2636-2641. DOI: 10.1039/C3NJ00424D

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Highlights of the 8th International Dendrimer Symposium

The 8th International Dendrimer Symposium was successfully held in Madrid on June 23–27 with Prof. Maria Angeles Muñoz-Fernandez as the chair. More than 200 scientists from all over the world participated in IDS-8 to present their latest achievements in dendrimer science.

The meeting opened with the “Ramon Areces” welcome lecture delivered by Prof. Virgil Percec, who depicted a fascinating material genome approach to construct complex dendrimer systems. Using dendritic motifs to create different types of fractal patterns was nicely exemplified by Prof. George Newkome, whereas capitalization on new strategies for dendrimer synthesis was the main focus in the lecture of Prof. René Roy. Prof. Dieter Schlüter reported the synthesis and characterization as well as discontinuities in dendronized polymers, whereas Dr. Anil Patri presented lessons learned from preclinical assessment of dendrimers.

Prof. Donald Tomalia gave a vivid and brief overview on the development of dendrimer science and focused in particular on the dendritic effects, which were further discussed in the lectures of Dr. Anne-Marie Caminade and Dr. Takuzo Aida. The meeting ended with the closing lecture of Dr. Jean-Pierre Majoral, who discussed the dendrimer space in nanomedicine and foresaw a bright future for dendrimers in therapeutic applications.

Poster prizes provided by several sponsors, including NJC, were awarded just before this closing lecture. The NJC laureats were profiled in an earlier post.

It is to note that, beside the excellent scientific program, there was a fantastic social program with a visit of the Prado museum and the Real Madrid stadium as well as the flamenco gala evening.

The next IDS meeting will be hosted by René Roy in Montreal, Canada in 2015. NJC will be there and we look forward to another excellent conference in the fascinating field of dendrimers.

Snapshots from the conference (courtesy of the organizers), including at far left the opening lecture by Virgil Percec (photo courtesy of Don Tomalia).

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Visit September’s issue of NJC.

An article by Antonio Frontera and co-workers (Universitat de les Illes Baleares, Palma de Mallorca, Spain) features on this month’s front cover. In this article, the authors report a theoretical study and Cambridge Structural Database (CSD) analysis of the anion–π binding ability of thiotrithiazyl salts. The anion–π interaction was noticed and described by Woolins and co-workers prior to the original theoretical studies where it was defined and characterized. Therefore, one aim of this manuscript is also to recognize and highlight the manuscript reported by Woolins and co-workers seventeen years ago.

Anion–π interactions in [S4N3]+ rings, Antonio Bauzá, David Quiñonero, Pere M. Deyà and Antonio Frontera, New J. Chem., 2013, 37, 2636-2641 DOI: 10.1039/C3NJ00424D (Article).

The inside cover was produced by Yasuhiro Shiraishi and co-workers (Osaka University, Toyonaka, Japan), presenting a spiropyran–cholesterol conjugate that behaves as a photoresponsive organogelator and is applicable as a material for information storage writable/erasable by light stimuli.

Spiropyran–cholesterol conjugate as a photoresponsive organogelator, Shigehiro Sumiya, Yasuhiro Shiraishi and Takayuki Hirai, New J. Chem., 2013, 37, 2642-2647 DOI: 10.1039/C3NJ00322A (Article).

Take your pick amongst the 7 letters and 38 full papers that composed this issue of September here.

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