Polymer chip to determine the onset of clotting in response to anticoagulants

Polymer chips embossed with micropillars enhance the distribution of fluorescently labelled fibrinogen, which can be used to determine the onset of clotting in response to anticoagulants.

Read this HOT paper from Anthony J. Killard and colleagues describing a technique for identifying the onset of in vivo clot formation.  One referee decribed it as a ‘clever yet practical approach’.
The paper will be free to access until the end of the month.

Development of a fluorescent method for detecting the onset of coagulation in human plasma on microstructured lateral flow platforms
Magdalena M. Dudek, Nigel J. Kent, Pan Gu, Z. Hugh Fan and Anthony J. Killard
Analyst, 2011
DOI: 10.1039/C0AN00907E

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