Reaction Chemistry & Engineering Blog

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from April – June 2017:

Why not take a look at the articles today and blog your thoughts and comments below.

Development of a reactor with carbon catalysts for modular-scale, low-cost electrochemical generation of H₂O₂
Zhihua Chen, Shucheng Chen, Samira Siahrostami, Pongkarn Chakthranont, Christopher Hahn, Dennis Nordlund, Sokaras Dimosthenis, Jens K. Nørskov, Zhenan Bao and Thomas F. Jaramillo
React. Chem. Eng., 2017, 2, 239-245
DOI: 10.1039/C6RE00195E

Halogenation of organic compounds using continuous flow and microreactor technology
David Cantillo and C. Oliver Kappe
React. Chem. Eng., 2017, 2, 7-19
DOI: 10.1039/C6RE00186F 

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 501-507
DOI: 10.1039/C6RE00132G

Suzuki–Miyaura cross-coupling optimization enabled by automated feedback
Brandon J. Reizman, Yi-Ming Wang, Stephen L. Buchwald and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 658-666
DOI: 10.1039/C6RE00153J

Aerobic oxidations in flow: opportunities for the fine chemicals and pharmaceuticals industries
Asterios Gavriilidis, Achilleas Constantinou, Klaus Hellgardt, King Kuok (Mimi) Hii, Graham J. Hutchings, Gemma L. Brett, Simon Kuhn and Stephen P. Marsden
React. Chem. Eng., 2016, 1, 595-612
DOI: 10.1039/C6RE00155F

Synthesis of narrow sized silver nanoparticles in the absence of capping ligands in helical microreactors
Ke-Jun Wu, Geoffroy Michet De Varine Bohan and Laura Torrente-Murciano
React. Chem. Eng., 2017, 2, 116-128
DOI: 10.1039/C6RE00202A

Rapid multistep kinetic model generation from transient flow data
Christopher A. Hone, Nicholas Holmes, Geoffrey R. Akien, Richard A. Bourne and Frans L. Muller
React. Chem. Eng., 2017, 2, 103-108
DOI: 10.1039/C6RE00109B

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016, 1, 229-238
DOI: 10.1039/C5RE00048C

Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform
E. Fitzpatrick and S. V. Ley
React. Chem. Eng., 2016, 1, 629-635
DOI: 10.1039/C6RE00160B

Continuous flow hydrogenations using novel catalytic static mixers inside a tubular reactor
Avril, C. H. Hornung, A. Urban, D. Fraser, M. Horne, J.-P. Veder, J. Tsanaktsidis, T. Rodopoulos, C. Henry and D. R. Gunasegaram
React. Chem. Eng., 2017, 2, 180-188
DOI: 10.1039/C6RE00188B

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from January – March 2017:

Why not take a look at the articles today and blog your thoughts and comments below.

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 501-507
DOI: 10.1039/C6RE00132G

Aerobic oxidations in flow: opportunities for the fine chemicals and pharmaceuticals industries
Asterios Gavriilidis, Achilleas Constantinou, Klaus Hellgardt, King Kuok (Mimi) Hii, Graham J. Hutchings, Gemma L. Brett, Simon Kuhn and Stephen P. Marsden
React. Chem. Eng., 2016, 1, 595-612
DOI: 10.1039/C6RE00155F

Suzuki–Miyaura cross-coupling optimization enabled by automated feedback
Brandon J. Reizman, Yi-Ming Wang, Stephen L. Buchwald and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 658-666
DOI: 10.1039/C6RE00153J

The application of reaction engineering to biocatalysis
R. H. Ringborg and J. M. Woodley  
React. Chem. Eng., 2016, 1, 10-22
DOI: 10.1039/C5RE00045A

Halogenation of organic compounds using continuous flow and microreactor technology
David Cantillo and C. Oliver Kappe  
React. Chem. Eng., 2017, 2, 7-19
DOI: 10.1039/C6RE00186F

Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform
D. E. Fitzpatrick and S. V. Ley
React. Chem. Eng., 2016, 1, 629-635
DOI: 10.1039/C6RE00160B

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016, 1, 229-238
DOI: 10.1039/C5RE00048C

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor
Nicholas Holmes, Geoffrey R. Akien, A. John Blacker, Robert L. Woodward, Rebecca E. Meadows and Richard A. Bourne
React. Chem. Eng., 2016, 1, 366-371
DOI: 10.1039/C6RE00059B

A general [¹⁸F]AlF radiochemistry procedure on two automated synthesis platforms
L. Allott, C. Da Pieve, D. R. Turton and G. Smith  
React. Chem. Eng., 2017, 2, 68-74
DOI: 10.1039/C6RE00204H

Combining microfluidics and FT-IR spectroscopy: towards spatially resolved information on chemical processes
Adeline Perro, Gwenaelle Lebourdon, Sarah Henry, Sophie Lecomte, Laurent Servant and Samuel Marre
React. Chem. Eng., 2016, 1, 577-594
DOI: 10.1039/C6RE00127K

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from October – December 2016:

Why not take a look at the articles today and blog your thoughts and comments below.

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016,1, 501-507
DOI: 10.1039/C6RE00132G

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor
Nicholas Holmes, Geoffrey R. Akien, A. John Blacker, Robert L. Woodward, Rebecca E. Meadows and Richard A. Bourne
React. Chem. Eng., 2016,1, 366-371
DOI: 10.1039/C6RE00059B

The application of reaction engineering to biocatalysis
R. H. Ringborg and J. M. Woodley
React. Chem. Eng., 2016,1, 10-22
DOI: 10.1039/C5RE00045A

A spray-drying continuous-flow method for simultaneous synthesis and shaping of microspherical high nuclearity MOF beads
L. Garzón-Tovar, M. Cano-Sarabia, A. Carné-Sánchez, C. Carbonell, I. Imaz and D. Maspoch
React. Chem. Eng., 2016,1, 533-539
DOI: 10.1039/C6RE00065G

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016,1, 229-238
DOI: 10.1039/C5RE00048C

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide
Guilherme Nogueira, Audrey Favrelle, Marc Bria, João P. Prates Ramalho, Paulo J. Mendes, Andreia Valente and Philippe Zinck
React. Chem. Eng., 2016,1, 508-520
DOI: 10.1039/C6RE00061D

A convenient numbering-up strategy for the scale-up of gas–liquid photoredox catalysis in flow
Yuanhai Su, Koen Kuijpers, Volker Hessel and Timothy Noël
React. Chem. Eng., 2016,1, 73-81
DOI: 10.1039/C5RE00021A

A laboratory-scale continuous flow chlorine generator for organic synthesis
Franz J. Strauss, David Cantillo, Javier Guerra and C. Oliver Kappe
React. Chem. Eng., 2016,1, 472-476
DOI: 10.1039/C6RE00135A

Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement
M. Baumann and Ian R. Baxendale
React. Chem. Eng., 2016,1, 147-150
DOI: 10.1039/C5RE00037H

A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process
Jian-Siang Poh, Duncan L. Browne and Steven V. Ley
React. Chem. Eng., 2016,1, 101-105
DOI: 10.1039/C5RE00082C

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from July – September 2016:

Why not take a look at the articles today and blog your thoughts and comments below.

Towards scalable and controlled synthesis of metal–organic framework materials using continuous flow reactors
Peter W. Dunne, Edward Lester and Richard I. Walton
React. Chem. Eng., 2016,1, 352-360
DOI: 10.1039/C6RE00107F

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor
Nicholas Holmes, Geoffrey R. Akien, A. John Blacker, Robert L. Woodward, Rebecca E. Meadows and Richard A. Bourne
React. Chem. Eng., 2016,1, 366-371
DOI: 10.1039/C6RE00059B

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016,1, 229-238
DOI: 10.1039/C5RE00048C

Monolith-based ⁶⁸Ga processing: a new strategy for purification to facilitate direct radiolabelling methods
Ping He, Benjamin P. Burke, Gonçalo S. Clemente, Nathan Brown, Nicole Pamme and Stephen J. Archibald
React. Chem. Eng., 2016,1, 361-365
DOI: 10.1039/C6RE00081A

A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process
Jian-Siang Poh, Duncan L. Browne and Steven V. Ley
React. Chem. Eng., 2016,1, 101-105
DOI: 10.1039/C5RE00082C

Kinetics analysis and automated online screening of aminocarbonylation of aryl halides in flow
Jason S. Moore, Christopher D. Smith and Klavs F. Jensen
React. Chem. Eng., 2016,1, 272-279
DOI: 10.1039/C6RE00007J

Controlled generation and use of CO in flow
Steffen V. F. Hansen, Zoe E. Wilson, Trond Ulven and Steven V. Ley
React. Chem. Eng., 2016,1, 280-287
DOI: 10.1039/C6RE00020G

Structuring hybrid palladium nanoparticles in metallic monolithic reactors for continuous-flow three-phase alkyne hydrogenation
Davide Albani, Gianvito Vilé, Mario Alejandro Beltran Toro, Rolf Kaufmann, Sharon Mitchell and Javier Pérez-Ramírez
React. Chem. Eng., 2016,1, 454-462
DOI: 10.1039/C6RE00114A

Hydrogenation of 2-methyl-3-butyn-2-ol over a Pd/ZnO catalyst: kinetic model and selectivity study
S. Vernuccio, R. Goy, Ph. Rudolf von Rohr, J. Medlock and W. Bonrath
React. Chem. Eng., 2016,1, 445-453
DOI: 10.1039/C6RE00093B

Hydrogenation of the liquid organic hydrogen carrier compound dibenzyltoluene – reaction pathway determination by ¹H NMR spectroscopy
G. Do, P. Preuster, R. Aslam, A. Bösmann, K. Müller, W. Arlt and P. Wasserscheid
React. Chem. Eng., 2016,1, 313-320
DOI: 10.1039/C5RE00080G