Welcome to Issue 9 of Organic Chemistry Frontiers

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The latest OrgChemFront issue is published online now.

The cover story, Room temperature, open-flask C–H arylation of electron-deficient heteroarenes with triazenes: rapid synthesis of heterobiaryls is contributed by Rui Wang and John R. Falck.

Following highlight and review article are also included in the current issue:

The 2-phosphaethynolate anion: convenient synthesis and the reactivity
Zheng-Jun Quan and Xi-Cun Wang
Org. Chem. Front., 2014, 1, 1128-1131
DOI: 10.1039/C4QO00189C

Organometallic intermediate-based organic synthesis: organo-di-lithio reagents and beyond
Wen-Xiong Zhang and Zhenfeng Xi
Org. Chem. Front., 2014, 1, 1132-1139
DOI: 10.1039/C4QO00231H


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Hot OrgChemFront Articles for September

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Take best advantage of the free access to Organic Chemistry Frontiers, and read the HOT articles for September!


Two- and three-coordinate formal iron(I) compounds featuring monodentate aminocarbene ligands
Zhenbo Mo, Zhenwu Ouyang, Lei Wang, Kathlyn L. Fillman, Michael L. Neidig and Liang Deng
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00175C, Research Article



Generation of 1-amino-isoquinoline-N-oxides via a tandem reaction of 2-alkynylbenzaldoxime with secondary amines in the presence of silver(I) and copper(I)
Junjie Song, Congbin Fan, Gang Liu and Guanyinsheng Qiu
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00209A, Research Article


Facile solid-phase synthesis of PNA–peptide conjugates using pNZ-protected PNA monomers
Yi-Chao Huang, Cheng Cao, Xiang-Long Tan, Xiaoyu Li and Lei Liu
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00217B, Research Article


A sidearm-assisted phosphine for catalytic ylide intramolecular cyclopropanation
Jian-Bo Zhu, Hao Chen, Saihu Liao, Yu-Xue Li and Yong Tang
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00232F, Research Article


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Welcome to Issue 8 of Organic Chemistry Frontiers

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The latest OrgChemFront issue is published online now.

The cover story, N-Allenylnitrone acts as 2-azadiene in the Cu-catalyzed cascade reaction of O-propargylic oximes with azodicarboxylates is contributed by Itaru Nakamura, Takeru Jo, Dong Zhang and Masahiro Terada.

Following highlights are also included in the current issue:

Bottom-up chemical synthesis of three-dimensional conjugated carbon nanostructures: from carbon nanocages to carbon nanotubes
Wei Wang, Yu-Xuan Wang and Hai-Bo Yang
Org. Chem. Front., 2014, 1, 1005-1009
DOI: 10.1039/C4QO00181H

Pyridine synthesis by [4 + 2] cycloadditions of 1-azadienes: hetero-Diels Alder and transition metal-catalysed approaches
Jamie M. Neely and Tomislav Rovis
Org. Chem. Front., 2014, 1, 1010-1015
DOI: 10.1039/C4QO00187G


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Recent HOT articles in OrgChemFront

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Take best advantage of the free access to Organic Chemistry Frontiers, and read the recent HOT articles!



Copper-mediated difluoromethylation of electron-poor aryl iodides at room temperature
Xue-Liang Jiang, Zeng-Hao Chen, Xiu-Hua Xu and Feng-Ling Qing
Org. Chem. Front., 2014,1, 774-776
DOI: 10.1039/C4QO00153B, Research Article



Highly efficient and stereocontrolled oxidative coupling of tetrahydropyrroloindoles: synthesis of chimonanthines, (+)-WIN 64821 and (+)-WIN 64745
Deqian Sun, Changyu Xing, Xiaoqing Wang, Zhongquan Su and Chaozhong Li
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00165F, Research Article




Enyne [4 + 4] photocycloaddition with polycyclic aromatics
Buddha B. Khatri, Svitlana Kulyk and Scott McN. Sieburth
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00190G, Research Article


Stereospecific synthesis of highly functionalized benzo[3.1.0]bicycloalkanes via multistep cascade reactions
Jian-Bo Zhu, Hao Chen, Lijia Wang and Yong Tang
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00134F, Research Article


Stereocontrolled synthesis of propionate motifs from L-lactic and L-alanine aldehydes. A DFT study of the hydrogen transfer under endocyclic control
François Godin, Martin Duplessis, Cindy Buonomano, Thao Trinh, Karine Houde, Daniel Chapdelaine, Jacques Rodrigue, André Boutros and Yvan Guindon
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00142G, Research Article


Near-infrared absorbing heterocyclic quinoid donors for organic solar cell devices
Emel Ay, Shunsuke Furukawa and Eiichi Nakamura
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00182F, Research Article


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Top 10 most-read Organic Chemistry Frontiers articles – Q2 2014

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This month sees the following articles in Organic Chemistry Frontiers that are in the top 10 most accessed from April – June:

Catalytic fluorination of unactivated C(sp3)–H bonds
Jun-An Ma and Shen Li
Org. Chem. Front., 2014,1, 712-715
DOI: 10.1039/c4qo00078a

Iron-catalyzed/mediated oxidative transformation of C–H bonds
Fan Jia and Zhiping Li
Org. Chem. Front., 2014,1, 194-214
DOI: 10.1039/c3qo00087g

Direct activation of relatively unstrained carbon–carbon bonds in homogeneous systems
Alpay Dermenci, Jotham W. Coe and Guangbin Dong
Org. Chem. Front., 2014,1, 567-581
DOI: 10.1039/c4qo00053f

Recent advances in directed C–H functionalizations using monodentate nitrogen-based directing groups
Min Zhang, Yuanfei Zhang, Xiaoming Jie, Huaiqing Zhao, Gang Li and Weiping Su
Org. Chem. Front., 2014,1, 843-895
DOI: 10.1039/c4qo00068d

Vanadium-catalyzed C(sp3)–H fluorination reactions
Ji-Bao Xia, Yuyong Ma and Chuo Chen
Org. Chem. Front., 2014,1, 468-472
DOI: 10.1039/c4qo00057a

Visible-light photocatalytic oxidation of 1,3-dicarbonyl compounds and carbon–carbon bond formation
Marion Daniel, Louis Fensterbank, Jean-Philippe Goddard and Cyril Ollivier
Org. Chem. Front., 2014,1, 551-555
DOI: 10.1039/c4qo00071d

Recent advances in C–H fluorination
Aijun Lin, C. Bryan Huehls and Jiong Yang
Org. Chem. Front., 2014,1, 434-438
DOI: 10.1039/c4qo00020j

Sonogashira coupling in natural product synthesis
Dan Wang and Shuanhu Gao
Org. Chem. Front., 2014,1, 556-566
DOI: 10.1039/c3qo00086a

Direct alkenyl C–H functionalization of cyclic enamines with carboxylic acids via Rh catalysis assisted by hydrogen bonding
Zhi-Quan Lei, Jian-Heng Ye, Jian Sun and Zhang-Jie Shi
Org. Chem. Front., 2014,1, 634-638
DOI: 10.1039/c4qo00074a

Selective monofluorination of active methylene compounds: the important role of ZnCl2 in inhibiting overfluorination
Fanzhou Jiang, Yanchuan Zhao and Jinbo Hu
Org. Chem. Front., 2014,1, 625-629
DOI: 10.1039/c4qo00090k


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Welcome to Issue 7 of Organic Chemistry Frontiers

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The latest OrgChemFront issue is published online now.

The cover story, Design of a new series of chiral phosphite–olefin ligands and their application in asymmetric catalysis is contributed by Yue-Na Yu and Ming-Hua Xu.

Following highlights and review article are also included in the current issue:

Chopping unfunctionalized carbon–carbon bonds: a new paradigm for the synthesis of organonitriles
Philippe Bisseret, Guillaume Dureta and Nicolas Blanchard
Org. Chem. Front., 2014,1, 825-833
DOI: 10.1039/C4QO00158C

Modern multicomponent reactions for better drug syntheses
Tryfon Zarganes-Tzitzikas and Alexander Dömling
Org. Chem. Front., 2014,1, 834-837
DOI: 10.1039/C4QO00088A

Transition-metal-catalyzed direct β-functionalization of simple carbonyl compounds
Guobing Yan and Arun Jyoti Borah
Org. Chem. Front., 2014,1, 838-842
DOI: 10.1039/C4QO00154K

Recent advances in directed C–H functionalizations using monodentate nitrogen-based directing groups
Min Zhang, Yuanfei Zhang, Xiaoming Jie, Huaiqing Zhao, Gang Li and Weiping Su
Org. Chem. Front., 2014, 1, 843-895
DOI: 10.1039/C4QO00068D


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Welcome to Issue 6 of Organic Chemistry Frontiers

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The latest OrgChemFront issue is published online now.

The cover story, Cationic gold(I)-catalyzed enantioselective hydroalkylation of unactivated alkenes: influence of the chloride scavenger on the stereoselectivity is contributed by Vincent Gandon and his co-workers.

Following highlight and review article are also included in the current issue:

Catalytic fluorination of unactivated C(sp3)–H bonds
Jun-An Ma and Shen Li
Org. Chem. Front., 2014, 1, 712-715
DOI: 10.1039/C4QO00078A

Synthesis and modification of octafluoro[2.2]paracyclophane (parylene AF4)
Craig Hicks, Brendan Duffy and Gráinne C. Hargaden
Org. Chem. Front., 2014, 1, 716-725
DOI: 10.1039/C4QO00110A


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Hot OrgChemFront Articles for June

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Take best advantage of the free access to Organic Chemistry Frontiers, and read the hot articles for June!


A problem solving approach for the diastereoselective synthesis of (5′S)- and (5′R)-5′,8-cyclopurine lesions
Chryssostomos Chatgilialoglu, Carla Ferreri, Annalisa Masi, Anna Sansone, Michael A. Terzidis and Michail Tsakos
Org. Chem. Front., 2014,1, 698-702
DOI: 10.1039/C4QO00133H



Design of a new series of chiral phosphite–olefin ligands and their application in asymmetric catalysis
Yue-Na Yua and Ming-Hua Xu
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00135D


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Hot OrgChemFront Articles for May

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Take best advantage of the free access to Organic Chemistry Frontiers, and read the hot articles for May!


Palladium-catalyzed reductive cleavage of tosylated arenes using isopropanol as the mild reducing agent
Wing Kin Chow, Chau Ming So, Chak Po Laua and Fuk Yee Kwong
Org. Chem. Front., 2014,1, 464-467
DOI: 10.1039/C4QO00103F


Selective monofluorination of active methylene compounds: the important role of ZnCl2 in inhibiting overfluorination
Fanzhou Jiang, Yanchuan Zhaoa and Jinbo Hu
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00090K


A green fullerene derivative as a fluoride ion sensor
Liang Xu, Sisi Liang and Liangbing Gan
Org. Chem. Front., 2014, Advance Article
DOI: 10.1039/C4QO00111G


*Submit your work to OrgChemFront and benefit from rapid publishing, free colour and free access till the end of 2015*

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Welcome to Issue 5 of Organic Chemistry Frontiers

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The latest OrgChemFront issue is published online now.

The cover story, Concise synthesis of atorvastatin lactone under high-speed vibration milling conditions is contributed by Verónica Estévez, Mercedes Villacampaa and J. Carlos Menéndez.

The inside front cover this month features an article on Palladium-catalyzed reductive cleavage of tosylated arenes using isopropanol as the mild reducing agent by Wing Kin Chow, Chau Ming So, Chak Po Laua and Fuk Yee Kwong.

Following highlights and review article are also included in the current issue:

Sonogashira coupling in natural product synthesis
Dan Wang and Shuanhu Gao
Org. Chem. Front., 2014, 1, 556-566
DOI: 10.1039/C3QO00086A

Direct activation of relatively unstrained carbon–carbon bonds in homogeneous systems
Alpay Dermenci, Jotham W. Coe and Guangbin Dong
Org. Chem. Front., 2014, 1, 567-581
DOI: 10.1039/C4QO00053F
Enantioselective heterogeneous Brønsted acid catalysis
Anil Kumar Mutyala and Nitin T. Patil
Org. Chem. Front., 2014, 1, 582-586
DOI: 10.1039/C4QO00051J


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