Organic Chemistry Frontiers Blog

Organic Chemistry Frontiers is delighted to share with you the HOT article of September 2018!

You can access this publication for free till 30^th November 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org)

Enantioselective isoquinuclidine synthesis via sequential Diels–Alder/visible-light photoredox C–C bond cleavage: a formal synthesis of the indole alkaloid catharanthine
Simon J. Kim and Robert A. Batey
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00849C

Iridium-catalyzed oxidative Ar–H/Ar–H cross-coupling of primary benzamides with thiophenes
Guangying Tan, Chunhao Rana and Jingsong You
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00796A

Dual roles of ynoates: desymmetrization of dicarboxylic acids using trialkylamines as alkyl equivalents
Xianjun Xu, Liliang Huang, Xiaoying Yin, Erik V. Van der Eyckenbc and Huangdi Feng
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00919H

Organic Chemistry Frontiers is delighted to share with you the HOT article of August 2018!

You can access this publication for free till 31^st October 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org)

Asymmetric Diels–Alder cycloadditions of benzofulvene-based 2,4-dienals via trienamine activation

Org. Chem. Front., 2018, Advance Article

http://dx.doi.org/10.1039/C8QO00653A

Photoinduced fragmentation-rearrangement sequence of cycloketoxime esters

Org. Chem. Front., 2018, Advance Article

http://dx.doi.org/10.1039/C8QO00747K

Organic Chemistry Frontiers is delighted to share with you the HOT articles of June 2018!

You can access these publications for free till 31^st August 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Photoexcited perylene diimide radical anions for the reduction of aryl halides: a bay-substituent effect
Pei-Zhi Zhang, Rui Liu, Ling-Dong Sun, Hao Dong, Lin-Dong Li, Xiao-Yu Zheng, Ke Wu and Chun-Hua Yan
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00445E

Visible-light photocatalytic trifluoromethylthiolation of aryldiazonium salts: conversion of amino group into trifluoromethylthiol group
Xia Zhao, Xiancai Zheng, Miaomiao Tian, Yifan Tong, Bo Yang, Xianfu Wei, Di Qiu and Kui Lu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00401C

Diastereoselectivity in a cyclic secondary amine catalyzed asymmetric Mannich reaction: a model rationalization from DFT studies
Siwei Shu, Zhao Liu, Yukui Li, Zhuofeng Ke and Yan Liu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00424B

Facile synthesis of macrocyclic peptide toxins of GpTx-1 and its analogue
Chao Chen, Mei Hong, Xiaoqi Guo, Fangming Wu, Changlin Tian, Yangding Wang and Zhaoqing Xu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00415C

Chemical synthesis and biological evaluation of penta- to octa- saccharide fragments of Vi polysaccharide from Salmonella typhi
Gao-Lan Zhang, Meng-Man Wei, Chengcheng Song, Yu-Feng Ma, Xiu-Jing Zheng, De-Cai Xiong and Xin-Shan Ye
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00471D

Dysohonin A, a meroditerpenoid incorporating a 6,15,6-fused heterotricyclic ring system from Dysoxylum hongkongense
Jin-Xin Zhao, Cui-Ping Liu, Meng-Meng Zhang, Jia Li and Jian-Min Yue
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00469B

Access to sulfonylated furans or imidazo[1,2-a]pyridines via a metal-free three-component, domino reaction
Zhiming Cui, Baofu Zhu, Xuechen Li and Hua Cao
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00443A

Palladium-catalyzed reductive electrocarboxylation of allyl esters with carbon dioxide
Ke-Jin Jiao, Zhao-Ming Li, Xue-Tao Xu, Li-Pu Zhang, Yi-Qian Li, Kun Zhang and Tian-Sheng Mei
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00507A

Catalytic enantioselective α-sulfenylation of β-ketocarbonyls by chiral primary amines
Linfeng Cui, Yang’en You, Xueling Mi and Sanzhong Luo
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00496J

Organic Chemistry Frontiers is delighted to share with you the HOT articles of May 2018!

You can access these publications for free till 31^th July 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Efficient catalytic vicinal diamination of arylene diimides
Michael Kremer, Maximilian Kersten and Sigurd Höger
Org. Chem. Front., 2018,5, 1825-1829
http://dx.doi.org/10.1039/C8QO00222C

Azidoheteroarylation of unactivated olefins through distal heteroaryl migration
Min Wang, Zhen Wu, Bo Zhang and Chen Zhu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00301G

Selective formation of phthalimides from amines, aldehydes and CO by Pd-catalyzed oxidative C–H aminocarbonylation
Renyi Shi, Fan Liao, Huiying Niu and Aiwen Lei
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00282G

Selenium dioxide-promoted selective synthesis of mono- and bis-sulfenylindoles
Samuel Thurow, Filipe Penteado, Gelson Perin, Diego Alves, Claudio Santi, Bonifacio Monti, Carl H. Schiesser, Thiago Barcellos and Eder J. Lenardão
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00360B

Highly enantioselective Ir/f-amphox-catalyzed hydrogenation of ketoamides: efficient access to chiral hydroxy amides
Yang Hu, Xuguang Yin, Ziyi Chen, Xiu-Qin Dong and Xumu Zhang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00307F

A more reliable synthesis of a Gemini vitamin D analog, a potentially effective chemotherapeutic agent for the treatment of colorectal carcinomas
Hugo Santalla, Fátima Garrido, Generosa Gómez and Yagamare Fall
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00338F

Three-component reaction to synthesize E-vinyl silyl anti-1,2-diols via sequential [1,4]-O-to-O/[1,4]-C-to-O silyl migrations
Qiang Pu, Xiaoxiao Tang, Lu Gao and Zhenlei Song
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00332G

Convergent syntheses of 2,3-dihydrobenzofurans via a Catellani strategy
Chenggui Wu, Hong-Gang Cheng, Ruiming Chen, Han Chen, Ze-Shui Liu, Jingyang Zhang, Yuming Zhang, Yuxin Zhu, Zhi Geng and Qianghui Zhou
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00348C

The iridium-catalysed reductive coupling reaction of tertiary lactams/amides with isocyanoacetates
Xiu-Ning Hu, Tai-Long Shen, Dong-Cheng Cai, Jian-Feng Zheng and Pei-Qiang Huang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00312B

Asymmetric [4 + 2] cycloadditions with 3-furfural derivatives and α-cyano-α,β-unsaturated ketones
Chuan-Qi Duan, Xiao-Long He, Wei Du and Ying-Chun Chen
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00351C

Organic Chemistry Frontiers is delighted to share with you the HOT articles of April 2018!

You can access these publications for free till 3o^th June 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Enantioselective indium(I)-catalyzed [4 + 2] annulation of alkoxyallenes and β,γ-unsaturated α-keto esters
Sujia Li, Jian Lv and Sanzhong Luo
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00319J

The design of rigid cyclic tripyrrins: the importance of intermolecular interactions on aggregation and luminescence
Jun-Fei Wang, Yuhang Yao, Yingying Ning, Yin-Shan Meng, Chun-Liang Hou, Jing Zhang and Jun-Long Zhang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00313K

Iridium-catalysed conjugated alkynylation of α,β-unsaturated amide through alkene isomerization
Yun Chen, Zi-Xuan Wang, Qian Li, Li-Jin Xu and Bi-Jie Li
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00136G

Organic Chemistry Frontiers is delighted to share with you the HOT articles of March 2018!

You can access these publications for free till 31^st May 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Base-promoted [3 + 3] cyclization of cyclopropenones and cyclopropenethiones with amides for the synthesis of 6H-1,3-oxazin-6-ones and 6H-1,3-thiazin-6-ones
Ben Niu, Bo Jiang, Liu-Zhu Yu and Min Shi
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00091C

Research Article Isolation and biosynthesis of labdanmycins: four new labdane diterpenes from endophytic Streptomyces
Zi-Jun Xiong, Jianping Huang, Yijun Yan, Li Wang, Zhiyan Wang, Jing Yang, Jianying Luo, Jie Li and Sheng-Xiong Huang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00085A

Efficient access to chiral benzo[c]chromenes via asymmetric transfer hydrogenation of ketals
Yangshan Li, Miao Wan, Shutao Sun, Zhongjun Fu, Haofei Huang and Lei Liu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00096D

Copper-catalyzed asymmetric hydroboration of 1,3-enynes with pinacolborane to access chiral allenylboronates
Hui Leng Sang, Songjie Yu and Shaozhong Ge
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00167G

Total synthesis of teixobactin and its stereoisomers
L. Liu, S. Wu, Q. Wang, M. Zhang, B. Wang, G. He and G. Chen
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00145F

Silver-catalyzed ring-opening difluoromethylthiolation/trifluoromethylthiolation of cycloalkanols with PhSO₂SCF₂H or PhSO₂SCF₃
Bin Xu, Decai Wang, Yonghong Hu and Qilong Shen
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00115D

Research Article Catalyst-controlled synthesis of 4-amino-isoquinolin-1(2H)-one and oxazole derivatives
Ben Niu, Ruixing Liu, Yin Wei and Min Shi
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00125A

Mechanistic insights into the different chemoselectivities of Rh₂(II)-catalyzed ring expansion of cyclobutanol-substituted aryl azides and C–H bond amination of cyclopentanol-substituted aryl azides: a DFT study
Dafang Gao and Xiaoguang Bao
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00113H

Photoredox-catalyzed cascade annulation of methyl(2-(phenylethynyl)phenyl)sulfanes and methyl(2-(phenylethynyl)phenyl)selanes with sulfonyl chlorides: synthesis of benzothiophenes and benzoselenophenes
Jianxiang Yan, Jian Xu, Yao Zhou, Jinglong Chen and Qiuling Song
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00147B

Asperones A–E, five dimeric polyketides with new carbon skeletons from the fungus Aspergillus sp. AWG 1–15
Guo-Ping Yin, Ya-Rong Wu, Chao Han, Xiao-Bing Wang, Hong-Liang Gao, Yong Yin, Ling-Yi Kong and Ming-Hua Yang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00070K

Organic Chemistry Frontiers is delighted to share with you the HOT articles of February 2018!

You can access these publications for free till 30^th Apr 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Synthesis of chiral γ-aminophosphonates through the organocatalytic hydrophosphonylation of azadienes with phosphites
Zheng Gu, Ji Zhou, Guo-Fang Jiang and Yong-Gui Zhou
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01158J

A concise synthesis of indene-based polycyclic compounds via FeCl₃-catalyzed cascade cyclization
Xiang Su, Panpan Wu, Wenfeng Liu and Chao Chen
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00004B

ⁿBu₄NOTf-promoted radical self-hydrogen transferring isomerization under transition metal-free conditions
Hong-Xing Zheng, Chuan-Zhi Yao, Jian-Ping Qu and Yan-Biao Kang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01138E

A general and efficient Mn-catalyzed acceptorless dehydrogenative coupling of alcohols with hydroxides into carboxylates
Zhihui Shao, Yujie Wang, Yaqian Liu, Qian Wang, Xiaoling Fu and Qiang Liu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C8QO00023A

Syntheses and structures of [7]helicene and double helicene based on dithieno[2,3-b:2′,3′-d]thiophene
Xinming Liu, Huiliang Sun, Wan Xu, Shisheng Wan, Jianwu Shi, Chunli Li and Hua Wang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01049D

Isolation, structural elucidation, and synthetic study of salviyunnanone A, an abietane derived diterpenoid with a 7/5/6/3 ring system from Salvia yunnanensis
Fan Xia, Da-Wei Zhang, Chun-Yan Wu, Hui-Chun Geng, Wen-Dan Xu, Yu Zhang, Xing-Wei Yang, Hong-Bo Qin and Gang Xu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01140G

Organic Chemistry Frontiers is delighted to share with you the HOT articles of January 2018!

You can access these publications for free till 31^st Mar 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Radical rearrangement of N-sulfonyl-N-aryl propynamides: proceeding with homolytic N–SO₂ bond cleavage and 6-endo-dig cyclization toward 3-sulfonyl-2(1H)-quinolinones
Bingbing Wang, Shengnan Jin, Song Sun and Jiang Cheng
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01048F

Copper-catalyzed three-component phosphorylation–peroxidation of alkenes
Yan Chen, Yuanjin Chen, Shenglin Lu and Zhiping Li
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01045A

Rhodium(III)-catalyzed annulative coupling between arenes and sulfoxonium ylides via C–H activation
Guangfan Zheng, Miaomiao Tian, Youwei Xu, Xiaohong Chen and Xingwei Li
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01033H

ortho-Amino group functionalized 2,2′-bipyridine based Ru(II) complex catalysed alkylation of secondary alcohols, nitriles and amines using alcohols
Bivas Chandra Roy, Subhankar Debnath, Kaushik Chakrabarti, Bhaskar Paul, Milan Maji and Sabuj Kundu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01061C

Racemic trinorsesquiterpenoids from the Beihai sponge Spongia officinalis: structure and biomimetic total synthesis
Dong-Yu Sun, Guan-Ying Han, Na-Na Yang, Le-Fu Lan, Xu-Wen Li and Yue-Wei Guo
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01091E

Iron/zinc-catalyzed benzannulation reactions of 2-(2-oxo-alkyl)benzketones leading to naphthalene and isoquinoline derivatives
Changyuan Zhang, Lianfen Chen, Kai Chen, Huanfeng Jiang and Shifa Zhu
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01152K

N-Heterocyclic carbene promoted enantioselective desymmetrization reaction of diarylalkane-bisphenols
Shoulei Li, Bin Liu, Li Chen, Xin Li and Jin-Pei Cheng
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01083D

Organic Chemistry Frontiers is delighted to share with you the HOT articles of December 2017!

You can access these publications for free till 28^th February 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Visible-light-induced tandem phosphorylation cyclization of vinyl azides under mild conditions
Yonghong Li, Yuanyuan Zhu and Shang-Dong Yang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO01004D

The hexameric resorcinarene capsule as an artificial enzyme: ruling the regio and stereochemistry of a 1,3-dipolar cycloaddition between nitrones and unsaturated aldehydes
Pellegrino La Manna, Margherita De Rosa, Carmen Talotta, Carmine Gaeta, Annunziata Soriente, Giuseppe Floresta, Antonio Rescifina and Placido Neri
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO00942A

Organic Chemistry Frontiers is delighted to share with you the HOT articles of November 2017!

You can access these publications for free till 31^st January 2018 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

An effective approach to aryl-substituted propanoic acids via the Pd-catalyzed hydrocarboxylation of stilbenes
Jie Dai, Wenlong Ren, Jingfu Li and Yian Shi
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO00726D

Nickel-catalyzed direct difluoromethylation of aryl boronic acids with BrCF₂H
Jie Sheng, Hui-Qi Ni, Kang-Jie Bian, Yan Li, Yi-Ning Wang and Xi-Sheng Wang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO00934H

Enantioselective palladium-catalyzed C–H functionalization of pyrroles using an axially chiral 2,2′-bipyridine ligand
Hong-Qiang Shen, Cong Liu, Ji Zhou and Yong-Gui Zhou
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO00815E

Thiazolium salt-catalyzed [3 + 2 + 1] cyclization for the synthesis of trisubstituted 2-pyrones using arylglyoxals as a carbonyl source
Li-Chen Xu, Peng Zhou, Jia-Zhuo Li, Wen-Juan Hao, Shu-Jiang Tu and Bo Jiang
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO00899F

Synthesis of pyridine trans-tetrafluoro-λ⁶-sulfane derivatives via radical addition
Prajwalita Das, Masahiro Takada, Etsuko Tokunaga, Norimichi Saito and Norio Shibata
Org. Chem. Front., 2018, Advance Article
http://dx.doi.org/10.1039/C7QO00994A