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Explore the Highly Cited Articles in Organic Chemistry Frontiers

We are delighted to highlight the following highly cited research articles published in Organic Chemistry Frontiers since 2023. We hope you enjoy reading them.

Photoelectrochemical upcycling of PVC plastic waste for the synthesis of chlorinated quinolinone derivatives

Kai Zheng, Jingwen He, Lixi Zhang, Zhaoyang Wang, Pengfei Zhang, Jianyu Cao and Chao Shen

Org. Chem. Front., 2025,12, 3191-3197
https://doi.org/10.1039/D5QO00189G

Energy-transfer photocatalysis for Minisci C–H (amino)alkylation of heteroarenes using oxime esters as dual-role reagents

Jun Xu, Yuru Zhang, Ruiyuan Xu, Yuxin Wang, Jiabin Shen and Wanmei Li

Org. Chem. Front., 2024,11, 5122-5129
https://doi.org/10.1039/D4QO00836G

Arylgermylation of alkenes by a cooperative photoactivation and hydrogen atom transfer strategy

Jia Cao, Yan Liu, Zhixiang Wang and Le Liu

Org. Chem. Front., 2024,11, 7098-7106
https://doi.org/10.1039/D4QO01497A

(±)-Hypandrone A, a pair of polycyclic polyprenylated acylphloroglucinol enantiomers with a caged 7/6/5/6/6 pentacyclic skeleton from Hypericum androsaemum

Jiangchun Wei, Pingping Fan, Yahui Huang, Hanxiao Zeng, Rui Jiang, Zhengzhi Wu, Yonghui Zhang and Zhengxi Hu

Org. Chem. Front., 2024,11, 3459-3464
https://doi.org/10.1039/D4QO00444B

Transition-metal-, oxidant- and additive-free multi-component synthesis of alkyl heteroaryl BCPs enabled by visible-light-induced phosphine-catalyzed halogen-atom transfer

Jun Xu, Yu Hong, Ruiyuan Xu, Yuxin Wang, Yirui Guo, Jiabin Shen, Yuxuan Zhao and Wanmei Li

Org. Chem. Front., 2024,11, 6166-6176
https://doi.org/10.1039/D4QO01351D

Access to spiro-bicyclo[2.1.1]hexanes via BF3·Et2O-catalyzed formal [2π + 2σ] cycloaddition of bicyclo[1.1.0]butanes with benzofuran-derived oxa(aza)dienes

Jia-Yi Su, Jian Zhang, Zhi-Yun Xin, Hao Li, Hanliang Zheng and Wei-Ping Deng

Org. Chem. Front., 2024,11, 4539-4545
https://doi.org/10.1039/D4QO00511B

Iron-catalyzed fragmentation-alkynylation, -alkenylation and -alkylation cascade enabled by photoinduced ligand-to-metal charge transfer

Yining Zhu, Han Gao, Jia-Lin Tu, Chao Yang, Lin Guo,Yating Zhao and Wujiong Xia

Org. Chem. Front., 2024,11, 1729-1735
https://doi.org/10.1039/D3QO01822A

Photoinduced C–H heteroarylation of enamines via quadruple cleavage of CF2Br2

Wanqing Zuo, Lingling Zuo, Xiao Geng, Zhifang Li and Lei Wang

Org. Chem. Front., 2023,10, 6112-6116
https://doi.org/10.1039/D3QO01474F

An iron-catalyzed C–S bond-forming reaction of carboxylic acids and hydrocarbons via photo-induced ligand to metal charge transfer

Ao-Men Hu, Jia-Lin Tu, Mengqi Luo, Chao Yang, Lin Guo and Wujiong Xia

Org. Chem. Front., 2023,10, 4764-4773
https://doi.org/10.1039/D3QO01081C

Nickel-catalyzed cross-electrophile coupling of aryl thiols with aryl bromides via C–S bond activation

Hao Xu, Cai-Yu He, Bo-Jie Huo, Jia-Wen Jing, Chengping Miao, Weidong Rao, Xue-Qiang Chu, Xiaocong Zhou and Zhi-Liang Shen

Org. Chem. Front., 2023,10, 5171-5179
https://doi.org/10.1039/D3QO01236K

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Explore the Highly Cited Articles in Organic Chemistry Frontiers

We are delighted to highlight the following highly cited review articles published in Organic Chemistry Frontiers since 2023. We hope you enjoy reading them.

Remodelling molecular frameworks via atom-level surgery: recent advances in skeletal editing of (hetero)cycles

Rubal Sharma, Mitsuhiro Arisawa, Shinobu Takizawa and Mohamed S. H. Salem

Org. Chem. Front., 2025,12, 1633-1670
https://doi.org/10.1039/D4QO02157F

Advances in organocatalytic asymmetric [3 + 3] cycloadditions: synthesis of chiral six-membered (hetero)cyclic compounds

Zi-Qi Zhu, Tian-Zhen Li, Si-Jia Liu and Feng Shi

Org. Chem. Front., 2024,11, 5573-5604
https://doi.org/10.1039/D4QO00515E

Advances in photoinduced radical–polar crossover cyclization (RPCC) of bifunctional alkenes

Meng Liu, Xinke Ouyang, Chenglong Xuan and Chao Shu

Org. Chem. Front., 2024,11, 895-915
https://doi.org/10.1039/D3QO01929B

Visible-light induced direct C(sp3)–H functionalization: recent advances and future prospects

Jia-Lin Tu, Yining Zhu, Pengcheng Li and Binbin Huang

Org. Chem. Front., 2024,11, 5278-5305
https://doi.org/10.1039/D4QO01179A

Recent advances in carbon atom addition for ring-expanding single-atom skeletal editing

Ting Yuan and Lei Shi

Org. Chem. Front., 2024,11, 7318-7332
https://doi.org/10.1039/D4QO01806K

Modern photo- and electrochemical approaches to aryl radical generation

Krzysztof Grudzień, Andrei Zlobin, Jan Zadworny, Katarzyna Rybicka-Jasińska and Bartłomiej Sadowski

Org. Chem. Front., 2024,11, 5232-5277
https://doi.org/10.1039/D4QO00999A

Recent advances in N-heterocyclic carbene (NHC)-catalyzed fluorination and fluoroalkylation

Zefeng Jin, Fangfang Zhang, Xiao Xiao, Nengzhong Wang, Xin Lv and Liejin Zhou

Org. Chem. Front., 2024,11, 2112-2133
https://doi.org/10.1039/D3QO02098C

Electrochemical difunctionalization of alkenes and alkynes for the synthesis of organochalcogens involving C–S/Se bond formation

Jianchao Liu, Jie-Ping Wan and Yunyun Liu

Org. Chem. Front., 2024,11, 597-630
https://doi.org/10.1039/D3QO01844J

Recent advances in the electrochemical generation of 1,3-dicarbonyl radicals from C–H bonds

Qinhui Wan, Zhongyi Zhang, Zhong-Wei Hou and Lei Wang

Org. Chem. Front., 2023,10, 2830-2848
https://doi.org/10.1039/D3QO00408B

Recent developments on 1,2-difunctionalization and hydrofunctionalization of unactivated alkenes and alkynes involving C–S bond formation

Bo Dong, Jian Shen and Lan-Gui Xie

Org. Chem. Front., 2023,10, 1322-1345
https://doi.org/10.1039/D2QO01699K

Feng chiral N,N′-dioxide ligands: uniqueness and impacts

Dian-Feng Chen and Liu-Zhu Gong

Org. Chem. Front., 2023,10, 3676-3683
https://doi.org/10.1039/D3QO00566F

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2024 Organic Chemistry Frontiers Most-Popular Articles

To celebrate the Year of the Snake, we are delighted to highlight some of the most popular articles published in Organic Chemistry Frontiers by corresponding authors based in countries celebrating the Chinese New Year.

We hope you enjoy reading these articles and wish you a happy and prosperous year of the Snake.

Advances in organocatalytic asymmetric [3 + 3] cycloadditions: synthesis of chiral six-membered (hetero)cyclic compounds

Zi-Qi Zhu, Tian-Zhen Li, Si-Jia Liu and Feng Shi

Org. Chem. Front., 2024,11, 5573-5604
https://doi.org/10.1039/D4QO00515E

Visible-light induced direct C(sp3)–H functionalization: recent advances and future prospects

Jia-Lin Tu, Yining Zhu, Pengcheng Li and Binbin HuangOrg. Chem. Front., 2024,11, 5278-5305
https://doi.org/10.1039/D4QO01179A  
Advances in photoinduced radical–polar crossover cyclization (RPCC) of bifunctional alkenes

Meng Liu, Xinke Ouyang, Chenglong Xuan and Chao Shu

Org. Chem. Front., 2024,11, 895-915
https://doi.org/10.1039/D3QO01929B

 

Recent advances in N-heterocyclic carbene (NHC)-catalyzed fluorination and fluoroalkylation

Zefeng Jin, Fangfang Zhang, Xiao Xiao, Nengzhong Wang, Xin Lv and Liejin Zhou

Org. Chem. Front., 2024,11, 2112-2133
https://doi.org/10.1039/D3QO02098C

 

Transition-metal-, oxidant- and additive-free multi-component synthesis of alkyl heteroaryl BCPs enabled by visible-light-induced phosphine-catalyzed halogen-atom transfer

Jun Xu, Yu Hong, Ruiyuan Xu, Yuxin Wang, Yirui Guo, Jiabin Shen, Yuxuan Zhao and Wanmei Li

Org. Chem. Front., 2024,11, 6166-6176
https://doi.org/10.1039/D4QO01351D

 

Photoinduced difunctionalizations of unactivated olefins enabled by ligand-to-iron charge transfer and functional group migration strategies

Mengqi Luo, Shibo Zhu, Jiawen Yin, Chao Yang, Lin Guo and Wujiong Xia

Org. Chem. Front., 2024,11, 4748-4756
https://doi.org/10.1039/D4QO01025F

Dearomative difunctionalization of arenes via highly selective radical relay reactions

Ning Lei, Qian Zhang, Pan Tao, Cong Lu, Qian Lei and Ke Zheng

Org. Chem. Front., 2024,11, 4654-4662
https://doi.org/10.1039/D4QO00964A

Pd((R)-DTBM-SEGphos)Cl2-catalyzed kinetic resolution of tertiary propargylic alcohols

Jie Wang, Wei-Feng Zheng, Yuling Li, Yin-Long Guo, Hui Qian and Shengming Ma

Org. Chem. Front., 2024,11, 2477-2484
https://doi.org/10.1039/D4QO00082J

Access to spiro-bicyclo[2.1.1]hexanes via BF3·Et2O-catalyzed formal [2π + 2σ] cycloaddition of bicyclo[1.1.0]butanes with benzofuran-derived oxa(aza)dienes

Jia-Yi Su, Jian Zhang, Zhi-Yun Xin, Hao Li, Hanliang Zheng and Wei-Ping Deng

Org. Chem. Front., 2024,11, 4539-4545
https://doi.org/10.1039/D4QO00511B

Design of rigid chiral bipyridine-2NO tetradentate ligands: application in asymmetric catalysis

Yu-Heng Wang, Pan Hu, Xi-Rui Wang, Ke-Lan Xu, Qi-Lin Wang, Hui-Juan Wang and Xiong-Li Liu

Org. Chem. Front., 2024,11, 1314-1321
https://doi.org/10.1039/D3QO01748F

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Organic Chemistry Frontiers Best Covers of 2024

We are proud to announce the three best covers of Organic Chemistry Frontiers in 2024! The awarded works were chosen by our readers through a worldwide vote. To learn more about the science behind the winning pieces, read for free the cover stories up until 03 February 2025.

   Photoredox catalyzed release of carbon-based radicals from 2-substituted-1,3-imidazolidines

Adrián Luguera Ruiz, Elena Mariani, Stefano Protti and Maurizio Fagnoni

Org. Chem. Front., 2024, 11, 661-667
https://doi.org/10.1039/D3QO01856C

Photoredox/nickel dual-catalyzed deaminative cross-electrophile for allenylic alkylation with non-activated alkyl katritzky salts

Zhao-Zhao Zhou, Xiao-Feng Zhai, Ke-Jian Xia, Xian-Rong Song, Haixin Ding, Wan-Fa Tian, Shu-Liang Zhang, Yong-Min Liang and Qiang Xiao

Org. Chem. Front., 2024, 11, 5685-5694
https://doi.org/10.1039/D4QO00834K

Catalytic intermolecular hydrofunctionalizations of ynamides

Ying-Ying Zhao, Yu-Jing Jia and Yan-Cheng HuOrg. Chem. Front., 2024, 11, 2351-2374
https://doi.org/10.1039/D4QO00301B

Congratulations to the winners!

We would like to express our sincere appreciation for all the support and contribution from our authors, reviewers, and readers during 2024.

Looking forward to receiving your high-quality work in 2025.

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Professor Buddhadeb Chattopadhyay joins OCF as Associate Editor

Organic Chemistry Frontiers is delighted to announce the appointment of Professor Buddhadeb Chattopadhyay from Centre of Biomedical Research (CBMR), Lucknow, India as an Associate Editor. In his new role, Professor Chattopadhyay will contribute to the journal’s development through manuscripts management, strategic setting and more. Please join us in welcoming him!

Learn more about our new Associate Editor:

Buddhadeb obtained his B.Sc. (2001) in chemistry from the Burdwan University and M.Sc. (2003) in chemistry from Visva-Bharati University. In 2003, he left Visva-Bharati and enrolled in Kalyani University for his Ph.D. in the laboratories of Professor K. C. Majumdar. After postdoctoral research work around six years in the USA from 2009 to 2024 (University of Illinois at Chicago, USA and Michigan State University, East Lansing, USA), Buddhadeb started his independent research career at the Centre of Biomedical Research (CBMR), Lucknow, India, where he is currently holding the position of Associate Professor in the Department of Biological & Synthetic Chemistry.

Buddhadeb was the recipient of the Ramanujan Faculty award, DST Young Scientist Award, Thieme Chemistry Journal Award, SERB-STAR AWARD–2019 (Science and Technology Award for Research), SERB-TETRA AWARD–2022 (Technology Translation Award), Fellow of National Academy of Sciences (FNASc), and Fellow of the Royal Society of Chemistry (FRSC).

His research interest includes the catalyst/ligand engineering for the C–H bond activation/functionalization, especially C–H bond borylations of organic molecules and metal-nitrene/carbene chemistry via metalloradical catalysis. To find more about Buddhadeb and his research work, visit The Chattopadhyay Group.

 

Read some of our new AE’s research in the papers below:

C–H borylation: a tool for molecular diversification

Saikat Guria, Mirja Md Mahamudul Hassan and Buddhadeb Chattopadhyay*

Org. Chem. Front., 2024,11, 929-953

10.1039/D3QO01931D

An iron(ǁ)-based metalloradical system for intramolecular amination of C(sp2)–H and C(sp3)–H bonds: synthetic applications and mechanistic studies

 

Sandip Kumar Das, Subrata Das, Supratim Ghosh, Satyajit Roy, Monika Pareek, Brindaban Roy, Raghavan B. Sunoj* and Buddhadeb Chattopadhyay*

Chem. Sci., 2022,13, 11817-11828

10.1039/D2SC03505G

 

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