Organic chemistry research for asymmetric synthesis

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We are delighted to share with you a collection of articles from Organic Chemistry Frontiers to showcase the recent development in asymmetric synthesis.

You can read these articles for free until 30th April.

Reviews articles

Multi-catalyst promoted asymmetric relay reactions
Qiu-Ju Liang, Yun-He Xu and Teck-Peng Loh
Org. Chem. Front., 2018,5, 2765-2768

Total synthesis of natural products via iridium catalysis
Changchun Yuan and Bo Liu
Org. Chem. Front., 2018,5, 106-131

Lu’s [3 + 2] cycloaddition of allenes with electrophiles: discovery, development and synthetic application
Yin Wei and Min Shi
Org. Chem. Front., 2017,4, 1876-1890

Catalytic asymmetric synthesis of hetero-substituted oxindoles
Renato Dalpozzo
Org. Chem. Front., 2017,4, 2063-2078

Research articles

Asymmetric Diels–Alder cycloadditions of benzofulvene-based 2,4-dienals via trienamine activatio
Jing-Fei Yue, Guang-Yao Ran, Xing-Xing Yang, Wei Du and Ying-Chun Chen
Org. Chem. Front., 2018,5, 1284-1287

Diastereoselectivity in a cyclic secondary amine catalyzed asymmetric Mannich reaction: a model rationalization from DFT studies
Siwei Shu, Zhao Liu, Yukui Li, Zhuofeng Ke and Yan Liu
Org. Chem. Front., 2018,5, 2148-2157

Copper-catalyzed asymmetric hydroboration of 1,3-enynes with pinacolborane to access chiral allenylboronates
Hui Leng Sang, Songjie Yu and Shaozhong Ge
Org. Chem. Front., 2018,5, 1284-1287

Synthesis of trans-disubstituted-2,3-dihydrobenzofurans by a formal [4 + 1] annulation between para-quinone methides and sulfonium salts
Ying Zhi, Kun Zhao, Carolina von Essen, Kari Rissanen and Dieter Enders
Org. Chem. Front., 2018,5, 1348-1351

1,6-Conjugated addition-mediated [4 + 1] annulation: an approach to 2,3-dihydrobenzofurans
Yang Wang, Yan Qiao, Donghui Wei and Mingsheng Tang
Org. Chem. Front., 2018,5, 623-628

Computational study on NHC-catalyzed enantioselective and chemoselective fluorination of aliphatic aldehydes
Lina Liu, Zhenbo Yuan, Rui Pan, Yuye Zeng, Aijun Lin, Hequan Yao and Yue Huang
Org. Chem. Front., 2017,4, 1987-1998

Asymmetric synthesis of CF3– and indole-containing tetrahydro-β-carbolines via chiral spirocyclic phosphoric acid-catalyzed aza-Friedel–Crafts reaction
En Xie, Abdul Rahman and Xufeng Lin
Org. Chem. Front., 2017,4, 1407-1410

Highly enantioselective nitro-Mannich reaction of ketimines under phase-transfer catalysis
Bin Wang, Tong Xu, Lei Zhu, Yu Lan, Jingdong Wang, Ning Lu, Zhonglin Wei, Yingjie Lin and Haifeng Duan
Org. Chem. Front., 2017,4, 1266-1271

Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions
Wei-Jie Huang, Qing Chen, Ning Lin, Xian-Wen Long, Wei-Gao Pan, Yan-Shi Xiong, Jiang Weng and Gui Lu
Org. Chem. Front., 2017,4, 472-482

The synthesis of unsymmetric diamides through Rh-catalyzed selective C–H bond activation of amides with isocyanates
Xiaoli Yu, Duo-Sheng Wang, Zhaojun Xu, Bobin Yang and Dawei Wang
Org. Chem. Front., 2017,4, 1011-1018

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