Inorganic Chemistry Frontiers Blog

First issue published for Inorganic Chemistry Frontiers

21 Jan 2014

The very first issue of Inorganic Chemistry Frontiers is now online. This new journal aims to publish high quality work on inorganic and organometallic molecules and solids with explicit applications.

We are confident that you will be impressed by the quality of the content. And the great news is that everyone can read the articles – they are all free to access.

This new journal has been developed as part of a collaboration between the Chinese Chemical Society and the Royal Society of Chemistry, in partnership with Peking University, China.

Make sure you stay in touch with the latest international research – register for Table of Content alerts now.

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The first application of bio-layer interferometry in medicinal inorganic chemistry

03 Jan 2014

By Wenjun Liu_Deputy Editor.

Bio-Layer Interferometry (BLI) is an optical analytical technique which measures the changes in light reflectance from an optical surface caused by macromolecule bindings to reveal the biomolecular interactions with interactome.

Dr. Aviva Levina and Prof. Peter A. Lay from the University of Sydney reported the first application of BLI technique into the studies of influences of medicinal metal ions on extracellular protein-protein interactions (PPIs). Their research shed light into the mechanism of the anti-metastatic activity of Ru(III) prodrugs.

In the PPI study on transferrin (Tf) with transferrin receptor 1 (TfR1), BLI was used to study the full cycle of Tf-TfR1 binding and dissociation in a single experiment and proved to be a simper and faster option for assessing the TfR1 binding for various metal-Tf complexes. Results of Tf-TfR1 binding studies suggest that blocking of Fe(III) delivery to fast-metabolising cancer cells through Ru(III)–Tf binding may be one of the mechanisms of anti-cancer activity of Ru(III), while the research on IgG–HSA binding supports the hypothesis that cross-linking of extracellular proteins by Ru(III) is involved in its anti-metastatic activity.

typical bio-layer interferometry response curves for the binding and dissociation of human Tf to recombinant human TfR1 in the presence or absence of metal ions

Typical BLI response curves for the binding and dissociation of human Tf to recombinant human TfR1 in the presence or absence of metal ions

To find out more details, read this HOT InorgChemFrontiers article for FREE today!

Influence of an anti-metastatic ruthenium(III) prodrug on extracellular protein–protein interactions: studies by bio-layer interferometry

Aviva Levina and Peter A. Lay

Inorg. Chem. Front., 2014, Advance Article

DOI: 10.1039/C3QI00054K

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Inorganic Chemistry Frontiers first articles now published

16 Dec 2013

By Valerie Simpson.

As we start a new year, it’s often a time for new beginnings.

So it’s appropriate that the first articles in Inorganic Chemistry Frontiers have just been published, and Issue 1 will follow shortly. The journal has been developed as part of a collaboration between The Chinese Chemical Society and the Royal Society of Chemistry, in partnership with Peking University, China.

The subjects covered by the articles are diverse and have come from researchers around the world, attracted by the journal’s aims of speed, high quality and visibility.

There’s an article from China on lithium storage via TiO₂ nanosheets, a report on the use of bio-layer interferometry from Australia, and another on alkyne interactions with palladium complexes from the USA. Finally, there’s an article on the optical properties of Wells-Dawson polyoxometalates from China and a review from the UK on Fe and Co precatalysts for ethylene oligo-/polymerization.

All content of Inorganic Chemistry Frontiers is free to access* until the end of 2015, so everyone can benefit from the research.

Get your new year off to a great start by reading the articles now.

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*Free access is available to all institutions/organisations with registered IP addresses, and to RSC Publishing Personal Account holders. Not a customer? Register here.

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Inorganic Chemistry Frontiers is now open for submissions

12 Oct 2013

By Wenjun Liu_Deputy Editor.

We are delighted to announce that Inorganic Chemistry Frontiers is now open for submissions!

Editor-in-Chief, Professor Song Gao (Peking University), invites you to submit your latest research. Submissions to Inorganic Chemistry Frontiers’ Associate Editors are handled fairly, quickly and efficiently.

Articles on inorganic and organometallic molecules and solids with explicit applications are welcomed. This includes inorganic chemistry research at the interfaces of materials science, energy, nanoscience, catalysis and bio-inorganic chemistry. Papers should be of high significance and answer fundamental questions relevant to interdisciplinary applications. For more information on how to submit and author guidelines please see our instructions to authors.

Inorganic Chemistry Frontiers is part of the Frontiers project: a unique collaboration between the Chinese Chemical Society and the Royal Society of Chemistry. The Journal will publish the best inorganic chemistry research from China, Asia and the rest of the world to an international audience.

Be a part of this new collaboration – submit your work today!

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Inorganic Chemistry Frontiers Blog

First issue published for Inorganic Chemistry Frontiers

The first application of bio-layer interferometry in medicinal inorganic chemistry

Inorganic Chemistry Frontiers first articles now published

Inorganic Chemistry Frontiers is now open for submissions

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