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1st Inorganic Chemistry Frontiers International Symposium – 27 February in Beijing

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To mark the launch of Inorganic Chemistry Frontiers, a collaborative journal between the Chinese Chemical Society and Peking University (PKU), a new series of international symposia will take place annually in different countries. The aim is to bring together the world-leading scientists to communicate and discuss advancing research in inorganic chemistry as well as in interdisciplinary areas between inorganic chemistry with materials science, energy, nanoscience, catalysis and biochemistry.

The symposia are supported by Inorganic Chemistry Frontiers and the first meeting is being organized by the Royal Society of Chemistry and the College of Chemistry and Molecular Engineering, PKU.  It is a one-day FREE event and will feature a selection of lectures focusing on the inorganic chemistry research, given by internationally renowned speakers.

Date and Venue: 27 February 2014; Central multimedia lecture (room Z201), College of Chemistry and Molecular Engineering, PKU, Beijing, China.

To find out more about the speakers and programm, please visit the website in English or in Chinese, or simply contact us at InorgChemFrontiersED@rsc.org. Welcome to join us on this exciting event!


为了庆祝《无机化学前沿》期刊的创办,第一届“无机化学前沿国际论坛”将于2月27日于北京大学化学与分子工程学院隆重举行。

此次论坛为期一天,将关注无机化学领域及无机化学与纳米科学,材料科学,能源科学,催化和生物化学等交叉研究领域的前沿动态,并探讨当今无机化学领域所面临的挑战。希望此次会议能够给国内外科学家们提供一个开放的交流平台,并促进更多的国际合作。

此次论坛将向所有参会人员免费开放

日期与地点2014年2月27日,北京大学化学与分子工程学院,C区Z201 中区多功能厅。

欢迎登陆相关网页查看更多关于报告人和会议日程安排的信息(中文网页英文网页)。如有任何疑问欢迎随时联系我们(InorgChemFrontiersED@rsc.org)。期待您的参与和支持!

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The first application of bio-layer interferometry in medicinal inorganic chemistry

Bio-Layer Interferometry (BLI) is an optical analytical technique which measures the changes in light reflectance from an optical surface caused by macromolecule bindings to reveal the biomolecular interactions with interactome.

Dr. Aviva Levina and Prof. Peter A. Lay from the University of Sydney reported the first application of BLI technique into the studies of influences of medicinal metal ions on extracellular protein-protein interactions (PPIs). Their research shed light into the mechanism of the anti-metastatic activity of Ru(III) prodrugs.

In the PPI study on transferrin (Tf) with transferrin receptor 1 (TfR1), BLI was used to study the full cycle of Tf-TfR1 binding and dissociation in a single experiment and proved to be a simper and faster option for assessing the TfR1 binding for various metal-Tf complexes. Results of Tf-TfR1 binding studies suggest that blocking of Fe(III) delivery to fast-metabolising cancer cells through Ru(III)–Tf binding may be one of the mechanisms of anti-cancer activity of Ru(III), while the research on IgG–HSA binding supports the hypothesis that cross-linking of extracellular proteins by Ru(III) is involved in its anti-metastatic activity.

typical bio-layer interferometry response curves for the binding and dissociation of human Tf to recombinant human TfR1 in the presence or absence of metal ions

Typical BLI response curves for the binding and dissociation of human Tf to recombinant human TfR1 in the presence or absence of metal ions

To find out more details, read this HOT InorgChemFrontiers article for FREE today!     

Influence of an anti-metastatic ruthenium(III) prodrug on extracellular protein–protein interactions: studies by bio-layer interferometry      

Aviva Levina and Peter A. Lay  

Inorg. Chem. Front., 2014, Advance Article  

DOI: 10.1039/C3QI00054K  

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Inorganic Chemistry Frontiers is now open for submissions

We are delighted to announce that Inorganic Chemistry Frontiers is now open for submissions!

Editor-in-Chief, Professor Song Gao (Peking University), invites you to submit your latest research. Submissions to Inorganic Chemistry Frontiers’ Associate Editors are handled fairly, quickly and efficiently.

Articles on inorganic and organometallic molecules and solids with explicit applications are welcomed. This includes inorganic chemistry research at the interfaces of materials science, energy, nanoscience, catalysis and bio-inorganic chemistry. Papers should be of high significance and answer fundamental questions relevant to interdisciplinary applications. For more information on how to submit and author guidelines please see our instructions to authors.

Inorganic Chemistry Frontiers is part of the Frontiers project: a unique collaboration between the Chinese Chemical Society and the Royal Society of Chemistry. The Journal will publish the best inorganic chemistry research from China, Asia and the rest of the world to an international audience.

Be a part of this new collaboration – submit your work today!

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