PPS issue 12 is now online. The last issue of 2011 features work on the front cover from Jacques Piette and co-workers from the University of Liège and the Catholic University of Leuven in Belgium.
Their article ‘5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma’ which was featured on the PPS blog earlier this month gives new insights in to the mechanism of action of 5-aminolevulinic acid (5-ALA) based photodynamic therapy (PDT) against glioblastoma revealing the involvement of receptor-interacting protein 3 (RIP3) in necrosis induction. Read more about it here, the full article is free to access until 6th January 2012!