Archive for the ‘Hot Article’ Category

In vitro studies of a potential bone substitute

Just published

Two-layer membranes of calcium phosphate/collagen/PLGA nanofibres: in vitro biomineralisation and osteogenic differentiation of human mesenchymal stem cells

N Hild, O D Schneider, D Mohn, N A Luechinger, F M Koehler, S Hofmann, J R Vetsch, B W Thimm, R Müller and W J Stark

Nanoscale, 2011, DOI: 10.1039/C0NR00615G, Advance Article

A study evaluating the in vitro biomedical performance of a potential biomaterial that mimics bone tissue.

The material, a bilayer made of  poly(lactide-co-glycolide), calcium phosphate and collagen, could have applications in treatment of bone defects with complex geometries as wound dressing material.

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Hot Communication: controlled nano-net fabrication

Hot Communication, just published

Controllable fabrication of soap-bubble-like structured polyacrylic acid nano-nets via electro-netting
Shangbin Yang, Xianfeng Wang, Bin Ding, Jianyong Yu, Jingfang Qian and Gang Sun
Nanoscale, 2011, DOI: 10.1039/C0NR00730G , Advanced Article

Bin Ding and colleagues report a novel process for the controlled preparation of large-scale polyacrylic acid (PAA) nano-nets: “electro-netting”.

Soap-bubble-like structured PAA nano-nets made up of interlinked ultrathin nanowires are controllably prepared in a one-step process.

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More Advanced Articles

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A bright future for biological imaging with fluorescent nanoparticles

Nanoscale’s new Publishing Editor Philip Howes, talks about a recent article on conjugated polymer nanoparticles published in the journal…

This month, a Nanoscale Feature Article presents a very interesting account of recent investigations into a novel type of fluorescent nanoparticles.

Read the Feature Article now for free:
Amplified energy transfer in conjugated polymer nanoparticle tags and sensors
Zhiyuan Tian, Jiangbo Yu, Changfeng Wu, Craig Szymanski and Jason McNeill
Nanoscale, 2010, 2, 1999-2011

Conjugated polymers are a fascinating class of material which combine the electrical behaviour of metals with the ease of processing of plastics. These organic molecules exhibit semiconducting behaviour as they possess a band structure similar to traditional inorganic semiconductors, like silicon, which allows the formation of excitons. For this reason, conjugated polymers are being used for the production of optoelectronic devices, such as LEDs and photovoltaics.

However, the use of conjugated polymers is not confined to device applications. As the polymers exhibit extremely high fluorescence brightness under UV excitation, they have been used to make fluorescent nanoparticles for use in biological imaging. The physical properties of conjugated polymer nanoparticles compare very well with the best known alternatives, such as quantum dots or dye-doped silica, and as they are relatively benign they appear to be promising for uses in biological fluorescence imaging studies where nanoparticle toxicity may be a concern. Furthermore, tuning of the colour of these nanoparticles is easily achieved by changing the type of polymer used, and as there is a vast range of conjugated polymers commercially available, emission across the visible spectrum is easily obtainable.

In this Feature Article, the authors review recent investigations into conjugated polymer nanoparticles with particular reference to optical and energy transfer phenomena, and applications in fluorescence based imaging and sensing applications. The underlying science of how fluorescent conjugated polymers behave in nanoparticle form is both fascinating and complex, and this is dealt with extremely well in this paper. As the authors explain, the development of conjugated polymer nanoparticles is still in its infancy and some important advances need to be made, such as reliable encapsulation and bioconjugation. However, the paper lays out many positive arguments as to why this type of particle should have a bright future in the development of fluorescent nanoparticles for biological imaging studies.

Philip Howes
Publishing Editor, Nanoscale


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Nanoparticles make glowing leaves

Can street lights be replaced by trees? Scientists report in Nanoscale they believe they can by using gold nanoparticles.

Light emitting diodes are used in street and bicycle lights and have a higher efficiency than traditional light bulbs. Now Yen Hsun Su has synthesised gold nanoparticles shaped like sea urchins and diffused them into Bacopa caroliniana chloroplast which creates a bio-LED.

Chlorophyll shows bioluminescence upon high wavelength (400 nm) ultra violet excitation. In contrast, the gold nanoparticles are excited at shorter wavelengths and emit at 400 nm. By implanting the nanoparticles in the plants, the chlorophyll in the leaves can be induced to produce a red emission.

In addition, the nanoparticles were able to suppress emission blinking – a known problem for gold nanoparticles –as they have a strong surface plasmon resonance. Su says that this bio-LED could be used to make roadside trees luminescent at night once the efficiency is improved and are also planning to apply the same strategy to other plant biomolecules.

Read this exciting paper today for free:
Influence of surface plasmon resonance on the emission intermittency of photoluminescence from gold nano-sea-urchins
Y. H. Su, S.-L. Tu, S.-W. Tseng, Y.-C. Chang, S.-H. Chang and W.-M. Zhang, Nanoscale, 2010
DOI: 10.1039/C0NR00330A

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Issue 10, out now

Nanoscale Issue 10, just published

Cover Article
Polyelectrolyte and carbon nanotube multilayers made from ionic liquid solutions
Takuya Nakashima, Jian Zhu, Ming Qin, Szushen Ho and Nicholas A. Kotov
Nanoscale, 2010, 2, 2084-2090

Highlight
Amplified energy transfer in conjugated polymer nanoparticle tags and sensors
Zhiyuan Tian, Jiangbo Yu, Changfeng Wu, Craig Szymanski and Jason McNeill
Nanoscale, 2010, 2, 1999-2011

Read the issue now

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Physics Nobel Prize 2010 Web Collection: Graphene

Nobel Prize in Physics for 2010

Andre Geim and Konstantin Novoselov

“for groundbreaking experiments regarding the two-dimensional material graphene”


At Nanoscale we congratulate the new Nobel Laureates. To celebrate this great news for the nano-community, we have prepared a Web Collection on Graphene bringing together 17 high-quality graphene articles recently published in the journal.

Physics Nobel 2010 Web Collection: Graphene

Read the collection for free today

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2D materials: Nanoscale Review out now

2D materials: to graphene and beyond

R. Mas-Ballesté, C. Gómez-Navarro, J. Gómez-Herrero and F. Zamora

Nanoscale, 2010, Advance Article, DOI: C0NR00323A, Review

This review is an attempt to illustrate the different alternatives in the field of 2D materials. Graphene seems to be just the tip of the iceberg, and the discovery of alternative 2D materials is starting to show the rest of this iceberg. The review comprises the current state-of-the-art of the vast literature in concepts and methods already known for isolation and characterization of graphene, and rationalizes the quite disperse literature in other 2D materials such as metal oxides, hydroxides and chalcogenides, and metal–organic frameworks.

You can read this review now

See more Nanoscale Advanced Articles

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Nanoscale Issue 9, highlights

Nanoscale Issue 9, INSIDE FRONT COVER ARTICLE


Hydrothermal transformation from Au core–sulfide shell to Au nanoparticle-decorated sulfide hybrid nanostructures


Zhihong Bao, Zhenhua Sun, Manda Xiao, Linwei Tian and Jianfang Wang
Nanoscale, 2010, 2, 1650-1652

Au nanoparticle-decorated sulfide nanostructures with morphologies similar to those of sea cucumbers arehydrothermally synthesized with Au nanorods and metal thiobenzoates


Highlight: REVIEW


Label-free biological and chemical sensors


Heather K. Hunt and Andrea M. Armani
Nanoscale, 2010, 2, 1544-1559

The development of label-free biochemical sensors, including sensor modalities, measurand recognition techniques, and microfluidic delivery systems are discussed to provide a roadmap for future sensor design

Read the latest issue now

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Nanoscale Issue 9, out now

Nanoscale issue 9 out now

FRONT COVER ARTICLE

Complex ZnO nanotree arrays with tunable top, stem and branch structures

F. Zhao, J.-G. Zheng, X. Yang, X. Li, J. Wang, F. Zhao, K. S. Wong, C. Liang and M. Wu

Nanoscale, 2010, 2, 1674-1683

Suggesting simple strategies to rationally design novel andhierarchical nanostructures and their arrays.


Also highlighted: FEATURE ARTICLE

Probing the electronic structure of carbon nanotubes by nanoscale spectroscopy


P. Castrucci, M. Scarselli, M. De Crescenzi, M. El Khakani and F. Rosei

Nanoscale, 2010, 2, 1611-1625

How to access the nanoscale electronic structure of carbon nanotubes: a review of the latest advances.


Read the issue now here

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Advanced Article: in vivo targeted drug delivery


Water soluble nanoporous nanoparticle for in vivo targeted drug delivery and controlled release in B cells tumor context

F. De Angelis, A. Pujia, C. Falcone, E. Iaccino, C. Palmieri, C. Liberale, F. Mecarini, P. Candeloro, L. Luberto, A. de Laurentiis, G. Das, G. Scala and E. Di Fabrizio

Nanoscale, 2010, Advance Article, DOI: 10.1039/C0NR00161A



Nanoscale Advanced Article, out now
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