Archive for November, 2022

Detecting Cancerous Cells with Bio-compatible Gelatin-based Nanoprobes

An infographic highlighting gelatin-based nanoprobes that can detect cancerous cells during image-guided surgery

Protease-activated indocyanine green nanoprobes for intraoperative NIR fluorescence imaging of primary tumors
Kyekyoon (Kevin) Kim, Viktor Gruev, Hyungsoo Choi et al.
Nanoscale Adv., 2022,4, 4041-4050, DOI: 10.1039/d2na00276k

 

Meet the authors

This article reports the collaborative efforts of two research laboratories: Thin Film and Charged Particles (TFCP) Research Lab (PIs. Kyekyoon (Kevin) Kim and Hyungsoo Choi) and Biosensors Lab (PI. Viktor Gruev) at the University of Illinois at Urbana-Champaign. TFCP Lab consists of multidisciplinary biomedical researchers formulating versatile biomaterial-based micro/nanoparticles incorporating drugs, fluorophores, and live-cells for various biomedical applications including the treatment of type-1 diabetes, ischemic stroke, and cancer. The scientists in Biosensors Lab are developing novel bio-inspired imaging technologies, highly sensitive and capable of differentiating multiple tumor-specific fluorophores, to provide surgeons with enhanced intraoperative imaging experiences during cancer surgery.

 

 

(a) What aspect of your work are you most excited about at the moment and what do you find most challenging about your research?

The exciting part is having opportunities to collaborate with many experts from different fields of science and engineering. The harmonious teamwork and support allow us to explore new ideas and conduct innovative research. The challenging part is finding the balance between innovation and clinical translation. Novelty in research offers new insights, but that wouldn’t necessarily lead to it being clinically acceptable. To ensure that we are doing translational research, we have to consider its relevance and applicability to patient-oriented healthcare.

 

(b) How do you feel about Nanoscale Advances as a place to publish research on this topic?

Nanoscale Advances is one of the fastest-growing journals, encompassing a wide scope of topics in nanotechnology. With that being said, we are excited to be able to showcase our work on such a platform.

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Call for papers: A path towards smart tailored nanomaterials

From design to synthesis, functionalization strategies and advanced characterizations

Guest Edited by Professor Chiara Battocchio (Roma Tre University, Rome, Italy), Professor Ilaria Fratoddi (Sapienza University of Rome, Italy) and Professor Barbara Capone (Roma Tre University, Rome, Italy).

 

Submit before 15 July 2023

 

In the last decades, a considerable effort has been focused on nanostructured materials (NMs), trying to find the correlation between structure and unexpected characteristics, which otherwise would not be possible at longer scales. NMs possess unique and widely tunable physicochemical properties, enabling unconventional applications to be achieved, ranging from nanomedicine, environmental science, catalysis to optoelectronics and energy conversion.

The design, synthesis and functionalization methods of NMs are oriented to a smart tailoring of the morpho-structural properties with the aim of improving their processability and applicability. However, the “perfect” material suitable for each application, requires precise control on the molecular and electronic structure as well as of the morphology of the nanomaterial.

Novel functionalised NMs require innovative design techniques, that foresee the creation of new paths where theoretical approaches walk side by side with modern synthetic methodologies and characterizations. The last decades saw the rise of theoretical and computational as a powerful tool to either predict on a mesoscopic scale (coarse graining, multiscale) the main features that would optimise the functionalisation of the designed materials, or to focus on very specific (atomistic) mechanisms unveiling the origins of specific properties in the materials.

Among others, the wet synthesis methods of nanomaterials possess a unique versatility to obtain different shapes, sizes and external functionalizing layers, which in turn prove to be an easy path for the customization of their properties.

Recently, the possibility to conjugate spectroscopic techniques with microscopy at nanometric level, as for example by combining X-ray spectroscopy with electron microscopy (SPELEEM), elicits a huge interest. Another issue that is having a very big development is the possibility to carry on X-ray photoemission experiments in non-UHV conditions, as in near ambient photoelectron spectroscopy (NAP), using a cell or an electrospray beam of nanoparticles in solution.

This collection focuses on the design, synthesis and advanced characterizations of functional NMs, e.g. metal, metal oxides, and hybrid nanoparticles by means of state-of-the-art spectroscopic and imaging techniques.

 

You are welcome to submit an original research article within the scope.

 

If you are interested in contributing to this collection please get in touch with the Editorial Office by email.

 

Manuscripts should be submitted via the Royal Society of Chemistry’s online submission service and the Editorial Office informed by email. Please add a “note to the editor” in the submission form when you submit your manuscript to say that this is a submission for the themed collection. The Editorial Office and Guest Editors reserve the right to check suitability of submissions in relation to the scope of the collection and inclusion of accepted articles in the collection is not guaranteed. All manuscripts will be subject to the journal’s usual peer review process. Accepted manuscripts will be added to the online collection as soon as they are online, and they will be published in a regular issue of Nanoscale Advances.

Please note that article processing charges apply to all articles submitted to Nanoscale Advances if, following peer-review, they are accepted for publication. Details of the APC and discounted rates can be found here.

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Call for papers: Nanomaterials for gas sensing and delivery


Guest Editors: Run Zhang (The University of Queensland, Australia), Songjun Zeng (Hunan University, China), Rona Chandrawati (University of New South Wales, Australia)

To address challenges in the management of gases (including noxious gas and therapeutic gas), a series of nanoscale materials with fascinating structural, physical, and chemical characteristics have been developed for gas sensing and delivery in recent years. This themed collection in Nanoscale Advances aims to provide a forum for recent trends in the rapidly evolving field of nanomaterials for gas sensing and delivery. We welcome articles on the following topics:

  • synthetic strategies
  • theoretical understanding
  • regulation of nanomaterials with gas sensing properties
  • nanosensors for the detection and identification of gaseous molecules (e.g. gasotransmitters, noxious gases, gaseous pollutants, etc.)
  • theranostic nanotechnology for drug-like gases delivery for the treatment of various diseases (e.g. cancer, gastrointestinal and cardiovascular disorders, etc.)
  • nanomaterial engineered devices and scaffolds for gas detection and therapies
  • other gas-related sensing technology and treatment procedures

 

You are welcome to submit an original research article within the scope.

 

If you are interested in contributing to this collection please get in touch with the Editorial Office by email.

 

Manuscripts should be submitted via the Royal Society of Chemistry’s online submission service and the Editorial Office informed by email. Please add a “note to the editor” in the submission form when you submit your manuscript to say that this is a submission for the themed collection. The Editorial Office and Guest Editors reserve the right to check suitability of submissions in relation to the scope of the collection and inclusion of accepted articles in the collection is not guaranteed. All manuscripts will be subject to the journal’s usual peer review process. Accepted manuscripts will be added to the online collection as soon as they are online, and they will be published in a regular issue of Nanoscale Advances.

Please note that article processing charges apply to all articles submitted to Nanoscale Advances if, following peer-review, they are accepted for publication. Details of the APC and discounted rates can be found here.

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Call for papers: Nanoparticle-Based Cancer Therapies

Guest Editors: Catarina Pinto Reis (University of Lisbon, Portugal), Maria Manuela Gaspar (University of Lisbon, Portugal), Carlos A García-González (Universidade de Santiago de Compostela, Spain)

In this collection we welcome articles on the following topics:

• drug carriers
• drug delivery
• biopolymers
• nanomaterials
• local and systemic delivery
• in situ delivery
• passive drug delivery
• targeted drug delivery
• nanoscale dosage forms
• nanomedicine
• supramolecular structures
• polymer conjugated
• pre-clinical studies
• in vitro models
• medical devices
• regulatory affairs

 

You are welcome to submit an original research article within the scope.

 

If you are interested in contributing to this collection please get in touch with the Editorial Office by email.

 

Manuscripts should be submitted via the Royal Society of Chemistry’s online submission service and the Editorial Office informed by email. Please add a “note to the editor” in the submission form when you submit your manuscript to say that this is a submission for the themed collection. The Editorial Office and Guest Editors reserve the right to check suitability of submissions in relation to the scope of the collection and inclusion of accepted articles in the collection is not guaranteed. All manuscripts will be subject to the journal’s usual peer review process. Accepted manuscripts will be added to the online collection as soon as they are online, and they will be published in a regular issue of Nanoscale Advances.

Please note that article processing charges apply to all articles submitted to Nanoscale Advances if, following peer-review, they are accepted for publication. Details of the APC and discounted rates can be found here.

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