Next-generation vascular stents: Nanoscale article in Chemistry World

Vascular stents can be surgically inserted into blood vessels to treat atherosclerosis © Shutterstock

Scientists in the US and China have developed a biodegradable alloy for use in medical implants. The new alloy, called JDBM, mixes magnesium, neodymium, zinc and zirconium. JDBM degrades uniformly in physiological conditions so further surgery to remove implants made from it would not be necessary.

Atherosclerosis is a precursor to heart disease and occurs when artery walls thicken from cholesterol build-up. Surgical atherosclerosis treatment uses a mesh tube called a stent to restore blood flow in blocked blood vessels. While most currently used stents are non-degradable and require further surgery to remove them, stents made from JDBM by the teams of Rong Fan at Yale University and Guanyin Yuan at Shanghai Jiaotong University will degrade in the body so won’t need to be removed.

Interested to know more? Read the full news article by Emma Eley in Chemistry World here…

Read the article by L Mao et al. in Nanoscale:

Nanophasic biodegradation enhances durability and biocompatibility of magnesium alloys for the next-generation vascular stents
Lin Mao, Li Shen, Jialin Liu, Jian Zhang, Wenjiang Ding, Rong Fan and Guangyin Yuan
DOI: 10.1039/C3NR02912C

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