Nanoscale & Nanoscale Advances Blog

Gold nanoparticles functionalised with aptamers have been found to be highly effective inhibitors for human immunodeficiency virus type 1 reverse transcriptase. The nanoparticles particles have been shown to reduce the ability of the HIV virus to reproduce and infect new cells.

The scientists behind the work describe how inhibition is enhanced further by using combinations of different aptamers that each target different parts of the virus.

Find out more about this exciting work – read the Nanoscale article today:

Highly efficient inhibition of human immunodeficiency virus type 1 reverse transcriptase by aptamers functionalized gold nanoparticles
Yen-Chun Shiang, Chung-Mao Ou, Shih-Ju Chen, Ting-Yu Ou, Han-Jia Lin, Chih-Ching Huang and Huan-Tsung Chang
DOI: 10.1039/C3NR33403A