Alek
sandra “Alex” Szczuka is an Assistant Professor in the Civil and Environmental Engineering department at the University of Michigan. Her research, motivated by broad access to affordable water, uses fundamental chemistry and microbiology to inform treatment of non-traditional water sources to safeguard public health. Alex’s research team is especially interested in understanding the drivers of acute and chronic health risks in water and in advancing emerging treatment technologies. She collaborates with researchers, engineers, and utility practitioners. Alex received her Ph.D. and M.S. degrees in Civil and Environmental Engineering from Stanford University, and a B.S.E. degree in Chemical and Biological Engineering from Princeton University. Prior to starting her lab, Alex was a Presidential Postdoctoral Fellow at the University of Michigan.
Read Lauren’s Emerging Investigator Series article “Mass spectrometry coupled to infrared ion spectroscopy – distinguishing positional isomers of chlorinated nucleoside analogues – novel disinfection byproducts” and learn more about her in the interview below:
Your recent Emerging Investigator Series paper focuses on the use of infrared ion spectroscopy (IRIS) to distinguish between positional isomers of chlorinated nucleosides which are disinfection by-products (DBP) of emerging concern. How has your research evolved from your earliest work to your independent research?
My first article as an undergraduate examined mercury uptake by bacteria and introduced me to the intersection of chemistry and biology. Since then, my research interests have moved to engineered water systems. During my Ph.D., I studied disinfection byproduct (DBP) control in water reuse systems, and during my postdoc, I studied virus inactivation mechanisms. My independent research now combines these threads. My team seeks to understand the chemical and biological drivers of health risk in non-traditional water sources, where we develop tools to better characterize the mechanisms behind contaminant persistence and strategies that utilities can use to lower these risks. Infrared Ion Spectroscopy (IRIS) is one such tool.
What aspect of your work are you most excited about at the moment?
I am most excited about my team’s work on biomolecule oxidation. Biomolecule reactivity has underexplored implications for pathogen inactivation, emerging DBP formation, and biomedical research. We are beginning to apply advanced analytical chemistry techniques to understand this reactivity and explore the consequences of biomolecule modification.
In your opinion, what are the most important questions to be asked/answered in your field of research?
“How can we best adapt to threats to our water supplies?” The quality of our freshwater is becoming increasingly unpredictable, whether due to inputs such as agricultural runoff, wastewater, or seawater intrusion, or to more extreme weather events such as storms and droughts. At the same time, advances in analytical methods allow us to detect previously undetectable contaminants, as well as emerging ones. Deciding which contaminants to monitor and regulate, and how best to translate research results into practice, will determine our ability to build resilience into our water systems amid uncertainty.
What do you find most challenging about your research?
Environmental samples are complex: many biological and chemical contaminants are present at trace concentrations, matrix effects complicate their detection, and it is unclear which surrogates best represent the risks posed by pathogens and chemicals. Advances in analytical methods are narrowing gaps in identification, but linking complex mixtures to biological effects remains difficult.
In which upcoming conferences or events may our readers meet you?
There are really great conferences coming up over the next year. I am a fan of the Water Quality Technology Conference (WQTC), which has a great mix of researchers and practitioners and is a great place to form collaborations with those outside academia. The next meeting is in November in Memphis. A few collaborators and I will be hosting a session at the Spring 2027 American Chemical Society (ACS) meeting on oxidation chemistry: we have an awesome lineup of speakers from both the chemical and biological subfields, so if you are in the New Orleans area in March, please drop by!
How do you spend your spare time?
My days revolve around a happily spoiled dog, Jack, and many food-oriented activities: I have successfully grown carrots and one ear of corn this year and have been turning them into various soups. I always embrace classic Michigan activities: I recently went apple picking and am looking forward to cozying up with my two snow shovels this winter.
Which profession would you choose if you were not a scientist?
Science communication. We need more people who can share science clearly with the public.
Can you share one piece of career-related advice or wisdom with other early career scientists?
Build collaborations with both academics and practitioners. Some of the most compelling research questions come from engaging with those who confront these challenges in practice.









