N-Heterocycles via zeolite catalysts

N-Heterocycles are important in agrochemicals, pharmaceuticals, as solvents and reagents. The compounds are widely distributed in nature and the synthesis of specific N-heterocycles is a topic of great interest. This thorough review by V. V. Krishna Mohan Kandepi and Nama Narender examines the application of zeolite molecular sieves to produce a wide range of N-heterocyclic compounds. The authors discuss syntheses from pyridine to bis(indolyl)phenylmethane, an anti-oxidant useful in cancer prevention.

The advantages to using these shape selective acid catalysts include thermal stability, re-usability and they are environmentally friendly. To find out more access this Perspective for free in Catalysis Science & Technology, where all are articles are free to access for the duration of 2012.

Synthesis of N-heterocyclic compounds over zeolite molecular sieve catalysts: an approach towards green chemistry
V. V. Krishna Mohan Kandepi and Nama Narender
Catal. Sci. Technol., 2012, Advance Article
DOI: 10.1039/C2CY00162D, Perspective

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