Archive for 2012

Top ten most accessed articles in April

This month sees the following articles in ChemSocRev that are in the top ten most accessed:-

Recent developments in asymmetric multicomponent reactions
Corien de Graaff, Eelco Ruijter and Romano V. A. Orru
Chem. Soc. Rev., 2012,41, 3969-4009, DOI: 10.1039/C2CS15361K

Biological applications of magnetic nanoparticles
Miriam Colombo, Susana Carregal-Romero, Maria F. Casula, Lucía Gutiérrez, María P. Morales, Ingrid B. Böhm, Johannes T. Heverhagen, Davide Prosperi and Wolfgang. J. Parak
Chem. Soc. Rev., 2012,41, 4306-4334, DOI: 10.1039/C2CS15337H

Functionalized mesoporous silica materials for controlled drug delivery
Piaoping Yang, Shili Gai and Jun Lin
Chem. Soc. Rev., 2012,41, 3679-3698, DOI: 10.1039/C2CS15308D

Optical molecular sensing with semiconductor quantum dots (QDs)
Ronit Freeman and Itamar Willner
Chem. Soc. Rev., 2012,41, 4067-4085, DOI: 10.1039/C2CS15357B

Small molecule semiconductors for high-efficiency organic photovoltaics
Yuze Lin, Yongfang Li and Xiaowei Zhan
Chem. Soc. Rev., 2012,41, 4245-4272, DOI: 10.1039/C2CS15313K

Design of polymeric nanoparticles for biomedical delivery applications
Mahmoud Elsabahy and Karen L. Wooley
Chem. Soc. Rev., 2012, 41, 2545-2561, DOI: 10.1039/C2CS15327K

Ethylene glycol: properties, synthesis, and applications
Hairong Yue, Yujun Zhao, Xinbin Ma and Jinlong Gong
Chem. Soc. Rev., 2012,41, 4218-4244, DOI: 10.1039/C2CS15359A

Sub-nanometre sized metal clusters: from synthetic challenges to the unique property discoveries
Yizhong Lu and Wei Chen
Chem. Soc. Rev., 2012,41, 3594-3623, DOI: 10.1039/C2CS15325D

Organocatalytic umpolung: N-heterocyclic carbenes and beyond
Xavier Bugaut and Frank Glorius
Chem. Soc. Rev., 2012, 41, 3511-3522, DOI: 10.1039/C2CS15333E

Recent advances in transition-metal catalyzed reactions using molecular oxygen as the oxidant
Zhuangzhi Shi, Chun Zhang, Conghui Tang and Ning Jiao
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C2CS15224J

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to ChemSocRev? Then why not contact us today with your suggestions.

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Directing Biosynthesis – oral abstract deadline 11 May!

DBIII header

Please don’t miss this last opportunity to submit an oral abstract now to be part of a high profile conference featuring contributions from the most active groups in the UK, Europe, the USA and Japan working in this rapidly developing area.

This meeting builds on the two previous extremely successful conferences in a subject area which remains highly topical. As significant opportunities exist for engineering biosynthetic pathways in bacteria, fungi and plants for the directed biosynthesis of new natural products with new and beneficial properties. We expect the programme this year to generate a high profile event that you will not want to miss. 

Confirmed Invited speakers:

  • Ikuro Abe, University of Tokyo, Japan
  • Mervyn Bibb, John Innes Centre, UK
  • David W. Christianson, University of Pennsylvania, USA
  • Christian Hertweck, Friedrich Schiller University Jena, Germany
  • Ben Liu, The University of Texas at Austin, USA
  • Professor Jim Naismith, University of St Andrews, UK
  • Joern Piel, University of Bonn, Germany
  • Professor Chris Schofield, University of Oxford, UK
  • David H Sherman, University of Michigan, USA
  • Dr David R Spring, University of Cambridge, UK
  • Tom Simpson, FRS, University of Bristol, UK
  • Yi Tang, UCLA, USA

NOW CONFIRMED – Craig Townsend, John Hopkins University, USA

A special symposium will take place within the Directing Biosynthesis III programme, recognising the achievements of three 2011 RSC award winners. Each of the winners will give a keynote lecture within the symposium.

Find out more >

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Focus: Studying biology using chemical tools

Graphical abstract: P450BM3 (CYP102A1): connecting the dotsChemical techniques are critical for studying and manipulating biological systems. We’ve published a great selection of reviews at the interface of chemistry and biology, including these recent articles:

Mass spectrometry based tools to investigate protein–ligand interactions for drug discovery
Kamila J. Pacholarz, Rachel A. Garlish, Richard J. Taylor and Perdita E. Barran
Chem. Soc. Rev., 2012, DOI: 10.1039/C2CS35035A

Diversity-oriented synthesis: producing chemical tools for dissecting biology
Cornelius J. O’ Connor, Henning S. G. Beckmann and David R. Spring
Chem. Soc. Rev., 2012, DOI: 10.1039/C2CS35023H

Assays for human telomerase activity: progress and prospects
Xiaoming Zhou and Da Xing
Chem. Soc. Rev., 2012, DOI: 10.1039/C2CS35045A

Mass spectrometry-based proteomics: existing capabilities and future directions
Thomas E. Angel, Uma K. Aryal, Shawna M. Hengel, Erin S. Baker, Ryan T. Kelly, Errol W. Robinson and Richard D. Smith
Chem. Soc. Rev., 2012,41, 3912-3928

Autophagy-regulating small molecules and their therapeutic applications
Kyung-Hwa Baek, Jihye Park and Injae Shin
Chem. Soc. Rev., 2012,41, 3245-3263

Probing the kinome in real time with fluorescent peptides
Juan A. González-Vera
Chem. Soc. Rev., 2012,41, 1652-1664

Upconversion nanophosphors for small-animal imaging
Jing Zhou, Zhuang Liu and Fuyou Li
Chem. Soc. Rev., 2012,41, 1323-1349

Do you have an idea for a review? Let us know >

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Chem Soc Rev Emerging Investigator Lectureship winner 2012

Xiaogang LiuOn behalf of the Chem Soc Rev Editorial Board, I am delighted to announce that Professor Xiaogang Liu (National University of Singapore and Institute of Materials Research Engineering, A*STAR) has won the Chem Soc Rev Emerging Investigator Lectureship 2012.

This annual award recognises an emerging scientist who has made a significant contribution to their research field. The Editorial Board praised Professor Liu’s research in the field of nanoscience, particularly his development of luminescent upconversion nanoparticles and contributions to nanoparticle-based ultrasensitive detection of metal ions and biological molecules.

Professor Liu will present his award lecture at ISACS9: Challenges in Nanoscience taking place in Xiamen, China, on 31 August – 3 September.

Find out more about Professor Liu’s work in these review articles:
Upconversion nanoparticles in biological labeling, imaging, and therapy
Feng Wang, Debapriya Banerjee, Yongsheng Liu, Xueyuan Chen and Xiaogang Liu
Analyst, 2010,135, 1839-1854

Emerging functional nanomaterials for therapeutics
Xuejia Xue, Feng Wang and Xiaogang Liu
J. Mater. Chem., 2011,21, 13107-13127

Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals
Feng Wang and Xiaogang Liu
Chem. Soc. Rev., 2009,38, 976-989

Registration is open for Challenges in Nanoscience (ISACS9) – sign up today to hear Professor Liu’s award lecture plus a host of other world leading experts

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Top ten most accessed articles in March

This month sees the following articles in ChemSocRev that are in the top ten most accessed:-

Organocatalytic umpolung: N-heterocyclic carbenes and beyond
Xavier Bugaut and Frank Glorius
Chem. Soc. Rev., 2012, 41, 3511-3522, DOI: 10.1039/C2CS15333E

Recent advances in transition-metal catalyzed reactions using molecular oxygen as the oxidant
Zhuangzhi Shi, Chun Zhang, Conghui Tang and Ning Jiao
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C2CS15224J

C-C, C-O and C-N bond formation via rhodium(iii)-catalyzed oxidative C-H activation
Guoyong Song, Fen Wang and Xingwei Li
Chem. Soc. Rev., 2012, 41, 3651-3678, DOI: 10.1039/C2CS15281A

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation
Nazila Kamaly, Zeyu Xiao, Pedro M. Valencia, Aleksandar F. Radovic-Moreno and Omid C. Farokhzad
Chem. Soc. Rev., 2012, 41, 2971-3010, DOI: 10.1039/C2CS15344K

Graphene-based composites
Xiao Huang, Xiaoying Qi, Freddy Boey and Hua Zhang
Chem. Soc. Rev., 2012, 41, 666-686, DOI: 10.1039/C1CS15078B

Biological and chemical sensors based on graphene materials
Yuxin Liu, Xiaochen Dong and Peng Chen
Chem. Soc. Rev., 2012, 41, 2283-2307, DOI: 10.1039/C1CS15270J

Endocytosis at the nanoscale
Irene Canton and Giuseppe Battaglia
Chem. Soc. Rev., 2012, 41, 2718-2739, DOI: 10.1039/C2CS15309B

Supramolecular concepts and new techniques in mechanochemistry: cocrystals, cages, rotaxanes, open metal-organic frameworks
Tomislav Friščić
Chem. Soc. Rev., 2012, 41, 3493-3510, DOI: 10.1039/C2CS15332G

Surface functionalization of nanoparticles for nanomedicine
Rubul Mout, Daniel F. Moyano, Subinoy Rana and Vincent M. Rotello
Chem. Soc. Rev., 2012, 41, 2539-2544, DOI: 10.1039/C2CS15294K

Design of polymeric nanoparticles for biomedical delivery applications
Mahmoud Elsabahy and Karen L. Wooley
Chem. Soc. Rev., 2012, 41, 2545-2561, DOI: 10.1039/C2CS15327K

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to ChemSocRev? Then why not contact us today with your suggestions.

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Nanomedicine themed issue

Chem Soc Rev issue 7 coverA highlight of the year so far for me is the publication of the Chem Soc Rev themed issue on Nanomedicine. Have you read it yet?

A lot of planning and hard work goes into the production of our themed issues. In fact, it has been over two years since I initially proposed this themed issue to the Chem Soc Rev Editorial Board. With the help, input and guidance of the fantastic guest editors – Frank Caruso, Taeghwan Hyeon and Vince Rotello – and the enthusiasm and dedication of all the authors, not to mention the referees and our Editorial Production team, the issue is now online. And I think it’s great. What about you?

As the guest editors state in their Editorial, nanomedicine is ‘poised to revolutionise healthcare and medicine through transformative new diagnostic and therapeutic tools’. Chemistry plays a crucial role, not just in terms of developing new materials but also the techniques and tools used to monitor and analyse their interactions in tissues. I hope that this themed issue will be a useful resource for those involved in research and teaching in this fascinating area.

Also of interest
Tailoring nanoparticles: Suits you sir!
ISACS9: Challenges in Nanoscience 31 August – 3 September, Xiamen, China

@ChemSocRev

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Top ten most accessed articles in February

This month sees the following articles in ChemSocRev that are in the top ten most accessed:-

Graphene-based composites
Xiao Huang, Xiaoying Qi, Freddy Boey and Hua Zhang
Chem. Soc. Rev., 2012, 41, 666-686, DOI: 10.1039/C1CS15078B

Recent advances in transition-metal catalyzed reactions using molecular oxygen as the oxidant
Zhuangzhi Shi, Chun Zhang, Conghui Tang and Ning Jiao
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C2CS15224J

Dynamic imine chemistry
Matthew E. Belowich and J. Fraser Stoddart
Chem. Soc. Rev., 2012, 41, 2003-2024, DOI: 10.1039/C2CS15305J

Surface functionalization of nanoparticles for nanomedicine
Rubul Mout, Daniel F. Moyano, Subinoy Rana and Vincent M. Rotello
Chem. Soc. Rev., 2012, 41, 2539-2544, DOI: 10.1039/C2CS15294K

The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy
Tennyson L. Doane and Clemens Burda
Chem. Soc. Rev., 2012, 41, 2885-2911, DOI: 10.1039/C2CS15260F

Conversion of biomass to selected chemical products
Pierre Gallezot
Chem. Soc. Rev., 2012, 41, 1538-1558, DOI: 10.1039/C1CS15147A

Recent advances in copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process
Chun Zhang, Conghui Tang and Ning Jiao
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C2CS15323H

Design of polymeric nanoparticles for biomedical delivery applications
Mahmoud Elsabahy and Karen L. Wooley
Chem. Soc. Rev., 2012, 41, 2545-2561, DOI: 10.1039/C2CS15327K

Signal amplification using functional nanomaterials for biosensing
Jianping Lei and Huangxian Ju
Chem. Soc. Rev., 2012, 41, 2122-2134, DOI: 10.1039/C1CS15274B

A review of electrode materials for electrochemical supercapacitors
Guoping Wang, Lei Zhang and Jiujun Zhang
Chem. Soc. Rev., 2012, 41, 797-828, DOI: 10.1039/C1CS15060J

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to ChemSocRev? Then why not contact us today with your suggestions.

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Graphene and related compounds – a review collection

Since the Nobel Prize for Physics was awarded to Andre Geim and Konstantin Novoselov “for groundbreaking experiments regarding the two-dimensional material graphene”, the eyes of the world (or, at least, the scientific world) have been focused on this so-called miracle material.

Graphical abstract: Graphene nanosheet: synthesis, molecular engineering, thin film, hybrids, and energy and analytical applications

This strange, stretchy, strong, see-through, conductive material – and its derivatives – has captured the attention of many research groups. Here’s a selection of reviews to inform and inspire:

Graphene-based composites
Xiao Huang, Xiaoying Qi, Freddy Boey and Hua Zhang
Chem. Soc. Rev., 2012, 41, 666-686

Graphene-based semiconductor photocatalysts
Quanjun Xiang , Jiaguo Yu and Mietek Jaroniec
Chem. Soc. Rev., 2012, 41, 782-796

Chemistry and physics of a single atomic layer: strategies and challenges for functionalization of graphene and graphene-based materials
Liang Yan, Yue Bing Zheng, Feng Zhao, Shoujian Li, Xingfa Gao, Bingqian Xu, Paul S. Weiss and Yuliang Zhao
Chem. Soc. Rev., 2012, 41, 97-114

Graphene nanosheet: synthesis, molecular engineering, thin film, hybrids, and energy and analytical applications
Shaojun Guo and Shaojun Dong
Chem. Soc. Rev., 2011, 40, 2644-2672

Electronic conduction in polymers, carbon nanotubes and graphene
Alan B. Kaiser and Viera Skákalová
Chem. Soc. Rev., 2011, 40, 3786-3801

The chemistry of graphene oxide
Daniel R. Dreyer, Sungjin Park, Christopher W. Bielawski and Rodney S. Ruoff
Chem. Soc. Rev., 2010, 39, 228-240

Graphene-based materials in electrochemistry
Da Chen, Longhua Tang and Jinghong Li
Chem. Soc. Rev., 2010, 39, 3157-3180

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Developing drug molecules for therapy with carbon monoxide

Carbon monoxide (CO) is known as the silent killer – it is colourless, odourless and tasteless and kills around 50 people each year in the UK. So are scientists crazy when they suggest that it could be used to save lives?

Graphical abstract: Developing drug molecules for therapy with carbon monoxideWell, no. Last century a physician discovered that our bodies produce CO. Not only that, but CO levels are higher in sick people than healthy. This suggested that CO could actually be therapeutic and sparked interest from pharmaceutical chemists.

The challenge is to deliver just the right amount of CO safely to diseased tissues. And as Gonçalo Bernardes and colleagues discuss in their Tutorial review, CO-releasing pro-drugs could be the solution. But how do they work and when will we see them in the clinic? Read the review to find out.

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Top ten most accessed articles in January

This month sees the following articles in ChemSocRev that are in the top ten most accessed:-

Trace metal impurities in catalysis
Isabelle Thomé, Anne Nijs and Carsten Bolm
Chem. Soc. Rev., 2012, 41, 979-987, DOI: 10.1039/C2CS15249E

Mesoporous silica nanoparticles in biomedical applications
Zongxi Li, Jonathan C. Barnes, Aleksandr Bosoy, J. Fraser Stoddart and Jeffrey I. Zink
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C1CS15246G

Coordination polymers: what has been achieved in going from innocent 4,4′-bipyridine to bis-pyridyl ligands having a non-innocent backbone?
N. N. Adarsh and Parthasarathi Dastidar
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C2CS15251G

Green Chemistry: present and future
Chao-Jun Li and Paul T. Anastas
Chem. Soc. Rev., 2012, 41, 1413-1414, DOI: 10.1039/C1CS90064A

Chemistry and physics of a single atomic layer: strategies and challenges for functionalization of graphene and graphene-based materials
Liang Yan, Yue Bing Zheng, Feng Zhao, Shoujian Li, Xingfa Gao, Bingqian Xu, Paul S. Weiss and Yuliang Zhao
Chem. Soc. Rev., 2012, 41, 97-114, DOI: 10.1039/C1CS15193B

Graphene-based composites
Xiao Huang, Xiaoying Qi, Freddy Boey and Hua Zhang
Chem. Soc. Rev., 2012, 41, 666-686, DOI: 10.1039/C1CS15078B

The golden age: gold nanoparticles for biomedicine
Erik C. Dreaden, Alaaldin M. Alkilany, Xiaohua Huang, Catherine J. Murphy and Mostafa A. El-Sayed
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C1CS15237H

Metal-organic framework growth at functional interfaces: thin films and composites for diverse applications
Darren Bradshaw, Ashesh Garai and Jia Huo
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C1CS15276A

Fluorescent and colorimetric sensors for detection of lead, cadmium, and mercury ions
Ha Na Kim, Wen Xiu Ren, Jong Seung Kim and Juyoung Yoon
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C1CS15245A

Multifunctional nanoparticles for multimodal imaging and theragnosis
Dong-Eun Lee, Heebeom Koo, In-Cheol Sun, Ju Hee Ryu, Kwangmeyung Kim and Ick Chan Kwon
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C2CS15261D

Why not take a look at the articles today and blog your thoughts and comments below.

Fancy submitting an article to ChemSocRev? Then why not contact us today with your suggestions.

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