Archive for December, 2012

Designing a new antifungal glycoconjugate vaccine

Potential conjugate vaccines against Candida albicans, a common pathogen which in its most virulent form may cause life-threatening bloodstream infections such as bacterial meningitis in infants and immunocompromised adults, are currently being developed.

As part of the upcoming Chem Soc Rev carbohydrate chemistry themed issue, this review article by members of the Bundle Research Group from the Alberta Glycomics Centre at the University of Alberta highlights the latest and most significant prospects for candidate vaccines against C. albicans. It also contextualises their work on conjugate vaccine design and evaluation within current knowledge on antibody-carbohydrate interactions and glycoconjugate vaccines development.

Their experimental findings show that conjugate vaccines containing disaccharide or trisaccharide attached to immunogenic proteins reduced fungal burden.

graphical abstract

Related PowerPoint slides on “β1,2-Mannans Conformationally Interesting Molecules” are also available as electronic supplementary information (ESI) – take a look at these for free.

Read this Chemical Society Reviews article today:

Designing a new antifungal glycoconjugate vaccine
Margaret A. Johnson and David R. Bundle
Chem. Soc. Rev., 2013, Advance Article
DOI: 10.1039/C2CS35382B

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Hua Zhang awarded Young Innovator Award

Hua Zhang, Advisory Board member of RSC journals Chem. Soc Rev. and Nanoscale, has been awarded the Small Young Innovator Award for 2012. We congratulate Hua on this achievement!

Hua is Associate Professor at the School of Materials Science and Engineering, Nanyang Technological University, Singapore, and won the award “For important contributions to novel low-dimensional nanomaterials.”

His research is highly interdisciplinary and currently focuses on synthesis of 2D nanomaterials and carbon materials (graphene and CNTs) and their applications in a wide range of fields from sensing to clean energy.

You can see some of Hua Zhang’s innovative research in these recent articles:

Graphene-based composites
Xiao Huang, Xiaoying Qi, Freddy Boey and Hua Zhang
Chem. Soc. Rev., 2012,41, 666-686
DOI: 10.1039/C1CS15078B, Critical Review

Fabrication of nanoelectrode ensembles by electrodepositon of Au nanoparticles on single-layer graphene oxide sheets
Zhijuan Wang, Juan Zhang, Zongyou Yin, Shixin Wu, Daniel Mandler and Hua Zhang
Nanoscale, 2012,4, 2728-2733
DOI: 10.1039/C2NR30142C, Paper

Hollow core–shell nanostructure supercapacitor electrodes: gap matters
Cao Guan, Xinhui Xia, Nan Meng, Zhiyuan Zeng, Xiehong Cao, Cesare Soci, Hua Zhang and Hong Jin Fan
Energy Environ. Sci., 2012,5, 9085-9090
DOI: 10.1039/C2EE22815G, Paper

Single-layer graphene oxide sheet: a novel substrate for dip-pen nanolithography
Hai Li, Xiehong Cao, Bing Li, Xiaozhu Zhou, Gang Lu, Cipto Liusman, Qiyuan He, Freddy Boey, Subbu S. Venkatraman and Hua Zhang
Chem. Commun., 2011,47, 10070-10072
DOI: 10.1039/C1CC12648B, Communication
From collection Molecule-based surface chemistry

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Chem Sov Rev Emerging Investigator Lectureship: Nomination Deadline 14th December

Chem Soc Rev is pleased to invite nominations for the 2013 Emerging Investigator Lectureship. This annual lectureship is given to recognise an emerging scientist who has made a significant contribution to their research field. 

Nomination Deadline: 14th December 2012
Nominate now
 

Previous winners include:

Xiaogang Liu
  2012 – Xiaogang Liu from the National University of Singapore and Institute of Materials Research Engineering, A*STAR 
  2011 – Cristina Nevado from the University of Zurich in Switzerland
  2010 – Shu-Hong Yu from the University of Science and Technology of China, in Hefei
  2009 – Matt Gaunt from the University of Cambridge in the UK
  2008 – Kazuya Kikuchi from Osaka University in Japan


Qualifying details
  

To be eligible for the Chem Soc Rev Emerging Investigator Lectureship, the candidate should have completed their PhD on or after 15th September 2004. 

Award details 

The recipient of the lectureship will be asked to present a lecture at an international meeting. The Chem Soc Rev Editorial Office will provide the sum of £1000 to the recipient for travel and accommodation costs. The recipient will be presented with a certificate and will also be asked to contribute a review to the journal. 

Selection 

The recipient of the lectureship will be selected and endorsed by the Chem Soc Rev Editorial Board. 

Nominations 

Those wishing to make a nomination should send details of the nominee, including a brief C.V. together with a letter supporting the nomination, to the Chem Soc Rev Editorial Office by 14th December 2012. Please note that self nomination is not permissible. 

Following the close of nominations, nominees will be contacted and asked to summarise their key achievements and identify up to their top 5 independent publications. They will also be asked to highlight the impact of their work and discuss how their research has evolved from their previous supervisor’s. 

     
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