The issue, guest edited by Professor Matthias Beller (Rostock University, Germany), includes 18 reviews highlighting recent key developments in cross-coupling reactions in organic synthesis. Authors include Stephen Buchwald, Lukas Goossen and Steven Nolan.
Also of interest: OBC Perspective: Tandem reactions initiated by copper-catalyzed cross-coupling: A new strategy towards heterocycle synthesis
This month sees the following articles in ChemSocRev that are in the top ten most accessed:-
Graphene-based composites
Xiao Huang, Xiaoying Qi, Freddy Boey and Hua Zhang
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C1CS15078B
Fabrication and application of inorganic hollow spheres
Jing Hu, Min Chen, Xiaosheng Fang and Limin Wu
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15103G
Nanocatalysts for Suzuki cross-coupling reactions
Aziz Fihri, Mohamed Bouhrara, Bijan Nekoueishahraki, Jean-Marie Basset and Vivek Polshettiwar
Chem. Soc. Rev., 2011, 40, 5181-5203, DOI: 10.1039/C1CS15079K
Aggregation-induced emission
Yuning Hong, Jacky W. Y. Lam and Ben Zhong Tang
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15113D
Fluorescent indicators based on BODIPY
Noël Boens, Volker Leen and Wim Dehaen
Chem. Soc. Rev., 2012, Advance Article, DOI: 10.1039/C1CS15132K
35 years of palladium-catalyzed cross-coupling with Grignard reagents: how far have we come?
Christiane E. I. Knappke and Axel Jacobi von Wangelin
Chem. Soc. Rev., 2011, 40, 4948-4962, DOI: 10.1039/C1CS15137A
Controlled synthesis of semiconductor nanostructures in the liquid phase
Zhongbin Zhuang, Qing Peng and Yadong Li
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15095B
Towards mild metal-catalyzed C–H bond activation
Joanna Wencel-Delord, Thomas Dröge, Fan Liu and Frank Glorius
Chem. Soc. Rev., 2011, 40, 4740-4761, DOI: 10.1039/C1CS15083A
New and unusual scaffolds in medicinal chemistry
Charles M. Marson
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15119C
Graphene-based semiconductor photocatalysts
Quanjun Xiang, Jiaguo Yu and Mietek Jaroniec
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15172J
Why not take a look at the articles today and blog your thoughts and comments below.
Fancy submitting an article to ChemSocRev? Then why not contact us today with your suggestions.
Chem Soc Rev is pleased to invite nominations for the 2012 Emerging Investigator Award. This annual award is given to recognise an emerging scientist who has made a significant contribution to their research field.
Previous winners include:
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2011 – Cristina Nevado from the University of Zurich in Switzerland 2010 – Shu-Hong Yu from the University of Science and Technology of China, in Hefei 2009 – Matt Gaunt from the University of Cambridge in the UK 2008 – Kazuya Kikuchi from Osaka University in Japan
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Qualifying details
To be eligible for the Chem Soc Rev Emerging Investigator Award, the candidate should have completed their PhD on or after 15th September 2003.
Award details
The recipient of the award will be asked to present a lecture at an international meeting. The Chem Soc Rev Editorial Office will provide the sum of £1000 to the recipient for travel and accommodation costs. The award recipient will be presented with a certificate and will also be asked to contribute a review to the journal.
Selection
The recipient of the award will be selected and endorsed by the Chem Soc Rev Editorial Board.
Nominations
Those wishing to make a nomination should send details of the nominee, including a brief C.V. together with a letter supporting the nomination, to the Chem Soc Rev Editorial Office by 15th December 2011. Please note that self nomination is not permissible.
Following the close of nominations, nominees will be contacted and asked to summarise their key achievements and identify up to their top 5 independent publications. They will also be asked to highlight the impact of their work and discuss how their research has evolved from their previous supervisor’s.
This month sees the following articles in ChemSocRev that are in the top ten most accessed:-
Small molecules in biology
Ali Tavassoli, Andrew D. Hamilton and David R. Spring
Chem. Soc. Rev., 2011, 40, 4269-4270, DOI: 10.1039/C1CS90028E
“Clicking” on/with polymers: a rapidly expanding field for the straightforward preparation of novel macromolecular architectures
Kristian Kempe, Andreas Krieg, C. Remzi Becer and Ulrich S. Schubert
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15107J
N-Heterocyclic carbene (NHC) ligands and palladium in homogeneous cross-coupling catalysis: a perfect union
George C. Fortman and Steven P. Nolan
Chem. Soc. Rev. , 2011, Advance Article, DOI: 10.1039/C1CS15088J
Microwave-assisted C–C bond forming cross-coupling reactions: an overview
Vaibhav P. Mehta and Erik V. Van der Eycken
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15094D
Graphene nanosheet: synthesis, molecular engineering, thin film, hybrids, and energy and analytical applications
Shaojun Guo and Shaojun Dong
Chem. Soc. Rev., 2011, 40, 2644-2672, DOI: 10.1039/C0CS00079E
Hierarchised luminescent organic architectures: design, synthesis, self-assembly, self-organisation and functions
Laura Maggini and Davide Bonifazi
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15031F
Update on selective oxidation using gold
Cristina Della Pina, Ermelinda Falletta and Michele Rossi
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15089H
Towards mild metal-catalyzed C–H bond activation
Joanna Wencel-Delord, Thomas Dröge, Fan Liu and Frank Glorius
Chem. Soc. Rev., 2011, 40, 4740-4761, DOI: 10.1039/C1CS15083A
Methods for investigating G-quadruplex DNA/ligand interactions
Pierre Murat, Yashveer Singh and Eric Defrancq
Chem. Soc. Rev. , 2011, Advance Article, DOI: 10.1039/C1CS15117G
Recent advances in Sonogashira reactions
Rafael Chinchilla and Carmen Nájera
Chem. Soc. Rev., 2011, Advance Article, DOI: 10.1039/C1CS15071E
Why not take a look at the articles today and blog your thoughts and comments below.
Fancy submitting an article to ChemSocRev? Then why not contact us today with your suggestions.
The term ‘synthetic biology’ is used to describe the combination of engineering and biology. By rationally designing systems using biological building blocks, we can gain a better understanding of existing biological life, enabling new therapeutic solutions to be found.
Professor Wilfried Weber and colleagues from the University of Freiburg discuss in their Chem Soc Rev article recent synthetic biology technologies that have been developed for the treatment of disease, such as cancer and gouty arthritis, and also for creating functional materials.
Synthetic biological systems can be thought of as molecular circuits in which an external signal is received and processed, providing an output response. Many of the systems Weber describes involve ways to control the expression of certain genes. In one such example, protein molecules bind to a specific DNA sequence and interrupt the action of the RNA polymerase enzyme, stopping the gene from being expressed. By introducing a small ligand molecule that can bind to the protein, the protein changes its shape and no longer binds to the DNA, providing an on/off switch.
Upon binding of tetracycline, the regulator protein is released from the DNA sequence allowing transcription of the gene.
Weber also summarises how DNA, RNA and protein building blocks can be used to produce stimulus-responsive hydrogels which can also be applied for therapeutic use.
To find out more, download the Chem Soc Rev review article.
Synthesising compounds asymmetrically has obvious advantages – scientists don’t have to go through the laborious and wasteful process of separating then discarding the ‘wrong’ enantiomer. Huge libraries of compounds can be tested for their ability to catalyse a reaction of interest but determining the enantiomeric excess (ee) of the products is a bottleneck in the process.
So researchers have been developing high-throughput ee screening methods that can analyse samples as quickly as they are generated, ideally at a rate of a thousand or more per day.
Eric Anslyn and colleagues explore this topic in their Chem Soc Rev critical review, specifically focusing on optical methods. Download the review to find out about the advantages and drawbacks of a variety of techniques.
Also of interest:
Discrimination of flavonoids and red wine varietals by arrays of differential peptidic sensors
Alona P. Umali, Sarah E. LeBoeuf, Robert W. Newberry, Siwon Kim, Lee Tran, Whitney A. Rome, Tian Tian, David Taing, Jane Hong, Melissa Kwan, Hildegarde Heymann and Eric V. Anslyn, Chem. Sci., 2011, 2, 439-445
