2023 RSC Chemical Biology Emerging Investigators collection

We’re pleased to announce that the second annual RSC Chemical Biology Emerging Investigators collection has now been published online!





This collection highlights the work of outstanding early career researchers from across the chemical biology community. We’ve provided links to just a few of these articles and the summary Profile below – be sure to visit the collection to read the rest!. All articles in RSC Chemical Biology are open access and free to read.

If you would like to nominate a colleague or yourself as an Emerging Investigator for our next collection, please contact us for further details. Emerging Investigators must be group leaders or principal investigators in the first 10 years of their independent career.


Contributors to the 2023 RSC Chemical Biology Emerging Investigators Collection

RSC. Chem. Biol., 2024, DOI: 10.1039/D4CB90013H


Biosynthesis of the fungal nonribosomal peptide penilumamide A and biochemical characterization of a pterin-specific adenylation domain

Stephanie C. Heard, Katharine L. Diehl and Jaclyn M. Winter

RSC. Chem. Biol., 2023, 4, 748–753, DOI: 10.1039/D3CB00088E


BrainBike peptidomimetic enables efficient transport of proteins across brain endothelium

Maria C. Lucana, Roberta Lucchi, Fabien Gosselet, Cristina Díaz-Perlas and Benjamí Oller-Salvia

RSC Chem. Biol., 2024, 5, 7–11, DOI: 10.1039/D3CB00194F


Methylated guanosine and uridine modifications in S. cerevisiae mRNAs modulate translation elongation

Joshua D. Jones, Monika K. Franco, Tyler J. Smith, Laura R. Snyder, Anna G. Anders, Brandon T. Ruotolo, Robert T. Kennedy and Kristin S. Koutmou

RSC. Chem. Biol., 2023, 4, 363–378, DOI: 10.1039/D2CB00229A


Click’n lock: rapid exchange between unsymmetric tetrazines and thiols for reversible, chemoselective functionalisation of biomolecules with on-demand bioorthogonal locking

Katerina Gavriel, Dustin C. A. van Doeselaar, Daniëlle W. T. Geers and Kevin Neumann

RSC. Chem. Biol., 2023, 4, 685–691, DOI: 10.1039/D3CB00062A

In addition to the researchers highlighted in our Profile article above, we’re pleased to feature this further contribution from Prof. Denise Okafor.

A portrait photograph of Denise Okafor

Denise Okafor is an assistant professor in the Departments of Biochemistry and Molecular Biology (BMB) and Chemistry at Pennsylvania State University. She received a B.S. in Biomedical chemistry from Oral Roberts University, followed by M.S. and Ph.D degrees in Chemistry from the Georgia Institute of Technology. As an NIH-IRACDA postdoctoral fellow at Emory University School of Medicine, she used molecular dynamics simulations to study ligand regulation and functional evolution in nuclear receptors. She began her independent career in 2020. Her lab combines MD simulations with biochemical experiments to understand mechanisms of transcriptional activation in nuclear receptors.

Read Prof. Okafor’s contribution below:

Ancient and modern mechanisms compete in progesterone receptor activation

RSC. Chem. Biol., 2024, 5,  DOI: 10.1039/D4CB00002A