Hot articles on screening antibiotic toxicity, commercializing point-of-care diagnostics & on-bead expression of recombinant proteins

We’re almost ready to wrap up for Easter here, but we have a few treats in the form of free* hot articles for you before we go!

Representation of a microfluidic platform for screening toxic antibiotic cocktailsFirst is a hot article from Piotr Garstecki and co-workers on their microfluidic device to screen hundreds of different cocktails of antibiotics to find combinations that will prove lethal to bacteria and overcome resistance:

Rapid screening of antibiotic toxicity in an automated microdroplet system
Krzysztof Churski,  Tomasz S. Kaminski,  Slawomir Jakiela,  Wojciech Kamysz,  Wioletta Baranska-Rybak,  Douglas B. Weibel and Piotr Garstecki
Lab Chip, 2012, 12, 1629-1637
DOI: 10.1039/C2LC21284F

Next is a Critical Review from Samuel Sia and colleagues on the achievements and challenges in commercialising microfluidic point-of-care diagnostics devices, with advice based on their own experiences:

Commercialization of microfluidic point-of-care diagnostic devices Point-of-care microfluidics
Curtis D. Chin,  Vincent Linder and Samuel K. Sia
Lab Chip, 2012, Advance Article
DOI: 10.1039/C2LC21204H

And the final hot article is from Dong-Myung Kim and colleagues who have developed a new method for expression and capture of recombinant proteins on the same bead:

On-bead expression of recombinant proteins in an agarose gel matrix coated on a glass slide
Kyung-Ho Lee,  Ka-Young Lee,  Ju-Young Byun,  Byung-Gee Kim and Dong-Myung Kim
Lab Chip, 2012, 12, 1605-1610
DOI: 10.1039/C2LC21239K

Happy reading!

* Articles are free to access for individual users following a simple registration process

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