Lab on a Chip Blog

The striking image on the outside front cover of this issue is courtesy of Aloke Kumar (Oak Ridge National Laboratory).  The Critical Review which it highlights discusses the fundamentals, applications and future of hybrid opto-electric manipulation techniques for microfluidics

Hybrid opto-electric manipulation in microfluidics—opportunities and challenges
Aloke Kumar, Stuart J. Williams, Han-Sheng Chuang, Nicolas G. Green and Steven T. Wereley
Lab Chip, 2011, 11, 2135-2148
DOI: 10.1039/C1LC20208A

The equally eye-catching image on the inside front cover is from Valérie Taly and Andrew D. Griffiths (ISIS, Strasbourg) et al., accompanying work on a droplet-based microfluidics method for digital PCR and a method for multiplexing quantitative digital PCR beyond the conventional limitations of color-encoded probes.

Quantitative and sensitive detection of rare mutations using droplet-based microfluidics
Deniz Pekin, Yousr Skhiri, Jean-Christophe Baret, Delphine Le Corre, Linas Mazutis, Chaouki Ben Salem, Florian Millot, Abdeslam El Harrak, J. Brian Hutchison, Jonathan W. Larson, Darren R. Link, Pierre Laurent-Puig, Andrew D. Griffiths and Valérie Taly
Lab Chip, 2011, 11, 2156-2166
DOI: 10.1039/C1LC20128J

Multiplex digital PCR: breaking the one target per color barrier of quantitative PCR
Qun Zhong, Smiti Bhattacharya, Steven Kotsopoulos, Jeff Olson, Valérie Taly, Andrew D. Griffiths, Darren R. Link and Jonathan W. Larson
Lab Chip, 2011, 11, 2167-2174
DOI: 10.1039/C1LC20126C

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