Porphyrin-anion transmembrane transport using PAMPA
The Parallel Artificial Membrane Permeability Assay (PAMPA) is a popular tool used in pharmaceutical industry to screen new drugs and evaluate their permeability across membranes. Vladimir Kral and colleagues from the Institute of Chemical Technology Prague, propose a low cost approach for screening transmembrane transport of supermolecular complexes using PAMPA. According to the authors, inorganic anions bound to a porphyrin receptor can be efficiently transported across membranes.
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Study of receptor mediated selective anion transmembrane transport using parallel artificial membrane permeability assay
Lenka Veverková , Kamil Záruba and Vladimír Král
Analyst, 2013, Advance Article
DOI: 10.1039/C3AN36760F
