Sensors & Diagnostics Blog

We’re pleased to inform you that this new themed collection from Sensors & Diagnostics has now been published online.

Read the collection here

This themed collection, guest edited by Jing Wang (Zhejiang University of Technology), Jiangjiang Zhang (Beijing Institute of Technology) and Yanmin Ju (China Pharmaceutical University) showcases cutting-edge research in the design, development, and deployment of lateral flow technologies. The contributions span a wide range of topics, including novel nanomaterials, signal amplification strategies, point-of-care diagnostics, and real-world applications in healthcare, food safety, and environmental monitoring.

Taken together, this collection highlights the remarkable versatility and continuing evolution of lateral flow assays, with contributions from researchers across the globe. We hope that readers will be inspired by these representative studies to further explore the vast potential of lateral flow assays-from enhancing sensitivity and integrating digital readouts to broadening applications in medical diagnostics, environmental monitoring, and food safety.

The articles in this collection are featured below. All articles in Sensors & Diagnostics are open access and free to read.

Introduction to “Lateral Flow Assays: Methods and Applications”

Jing Wang, Jiangjiang Zhang and Yanmin Ju

Sens. Diagn., 2025, DOI: 10.1039/D5SD90027A

The importance of antibody orientation for enhancing sensitivity and selectivity in lateral flow immunoassays

Zhao-Yu Lu and Yang-Hsiang Chan

Sens. Diagn., 2024, 3, 1613–1634 DOI: 10.1039/D4SD00206G

Improved point-of-care detection of P. gingivalis using optimized surface-enhanced Raman scattering in lateral flow assays

Lyndsay N. Kissell, Daewoo Han, Der Vang, Alexander W. R. Cikanek, Andrew J. Steckl and Pietro Strobbia

Sens. Diagn., 2024, 3, 839–849 DOI: 10.1039/D4SD00056K

Non-organic solvent extraction of capsaicinoids from oil combined with fluorescent lateral flow immunoassay strips for on-site identification of illegally recycled waste cooking oil

Yulian Wang, Yuxiang Wu, Deji Gesang, Zixuan Dong, Zhaoxu Qin, Qingchun Li, Jin Li, Qianxu Zhou and Guoqing Shi

Sens. Diagn., 2025, 4, 147–158 DOI: 10.1039/D4SD00306C

Rapid and automated interpretation of CRISPR-Cas13-based lateral flow assay test results using machine learning

Mengyuan Xue, Diego H. Gonzalez, Emmanuel Osikpa, Xue Gao and Peter B. Lillehoj

Sens. Diagn., 2025, 4, 171–181 DOI: 10.1039/D4SD00314D

Biotin/avidin-free sandwich aptamer-based lateral flow assay (ALFA) for the diagnosis of Trichomonas vaginalis

Christine Aubrey C. Justo, Vasso Skouridou, Piet Cools, Guy Mulinganya, Alexandra Ibáñez-Escribano and Ciara K. O’Sullivan

Sens. Diagn., 2025, 4, 216–228 DOI: 10.1039/D4SD00342J

Lateral flow assay-based detection of nuclear fusion oncoprotein: implications for screening of acute promyelocytic leukemia

Maede Chabi, Binh Vu, Kristen Brosamer, Sophia Song, Vijay Maranholkar, Zihua Zeng, Youli Zu, Rashmi Kanagal-Shamanna, Jacinta C. Conrad, Richard C. Willson and Katerina Kourentzi

Sens. Diagn., 2025, 4, 416–424 DOI: 10.1039/D4SD00357H

Selection of a DNA aptamer for aflatoxin B1 and the development of a lateral flow assay for the detection of aflatoxins in spiked peanut extract

Fiona Ebanks, Erin M. McConnell, Emily Mastronardi, Daniel Goudreau, Hadi Nasrallah, Velu Ranganathan and Maria C. DeRosa

Sens. Diagn., 2025, 4, 697–710 DOI: 10.1039/D4SD00271G