Top 10 Most-accessed Reaction Chemistry & Engineering articles – Q4 2016

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from October – December 2016:

Why not take a look at the articles today and blog your thoughts and comments below.

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016,1, 501-507
DOI: 10.1039/C6RE00132G

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor
Nicholas Holmes, Geoffrey R. Akien, A. John Blacker, Robert L. Woodward, Rebecca E. Meadows and Richard A. Bourne
React. Chem. Eng., 2016,1, 366-371
DOI: 10.1039/C6RE00059B

The application of reaction engineering to biocatalysis
R. H. Ringborg and J. M. Woodley
React. Chem. Eng., 2016,1, 10-22
DOI: 10.1039/C5RE00045A

A spray-drying continuous-flow method for simultaneous synthesis and shaping of microspherical high nuclearity MOF beads
L. Garzón-Tovar, M. Cano-Sarabia, A. Carné-Sánchez, C. Carbonell, I. Imaz and D. Maspoch
React. Chem. Eng., 2016,1, 533-539
DOI: 10.1039/C6RE00065G

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016,1, 229-238
DOI: 10.1039/C5RE00048C

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide
Guilherme Nogueira, Audrey Favrelle, Marc Bria, João P. Prates Ramalho, Paulo J. Mendes, Andreia Valente and Philippe Zinck
React. Chem. Eng., 2016,1, 508-520
DOI: 10.1039/C6RE00061D

A convenient numbering-up strategy for the scale-up of gas–liquid photoredox catalysis in flow
Yuanhai Su, Koen Kuijpers, Volker Hessel and Timothy Noël
React. Chem. Eng., 2016,1, 73-81
DOI: 10.1039/C5RE00021A

A laboratory-scale continuous flow chlorine generator for organic synthesis
Franz J. Strauss, David Cantillo, Javier Guerra and C. Oliver Kappe
React. Chem. Eng., 2016,1, 472-476
DOI: 10.1039/C6RE00135A

Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement
M. Baumann and Ian R. Baxendale
React. Chem. Eng., 2016,1, 147-150
DOI: 10.1039/C5RE00037H

A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process
Jian-Siang Poh, Duncan L. Browne and Steven V. Ley
React. Chem. Eng., 2016,1, 101-105
DOI: 10.1039/C5RE00082C

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Royal Society of Chemistry and ACS Publications commit to ORCID integration

Yesterday, the Royal Society of Chemistry and the American Chemical Society Publications Division, ACS Publications, both signed the ORCID Open Letter committing to unambiguous identification of all authors that publish in our journals.

The official press release can be found here: http://rsc.li/orcid

In brief, this partnership with ORCID will resolve ambiguity in researcher identification caused by name changes, cultural differences in name presentation, and the inconsistent use of name abbreviations, thereby ensuring their contributions are appropriately recognized and credited.

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Flow Chemistry Europe 2017

Reaction Chemistry & Engineering is proud to sponsor the Flow Chemistry Europe 2017 meeting, to be held by the Flow Chemistry Society at Magdalene College, University of Cambridge, UK, on 7–8 February 2017. Submit your poster abstract before 17 January 2017 for a chance to win a prize, courtesy of Reaction Chemistry & Engineering!

Conference Chairs:

  • Volker Hessel (Eindhoven University of Technology, Reaction Chemistry & Engineering Editorial Board)
  • Mimi Hii (Imperial College London, Reaction Chemistry & Engineering Advisory Board),

This meeting is dedicated to the integration of flow chemistry into everyday processes. By attending this industry-leading conference, you will benefit from the expert knowledge of academic and industry leaders who are pushing the boundaries of this rapidly evolving field. Agenda topics include:

  • Back to Einstein – Electrification of chemistry – making use of the smallest units, photons and electrons
  • Back to Health – Medicinal flow chemistry in the era of the FDA’s door opening towards emerging technologies
  • Back to Nature – End-to-end continuous-flow production

Keynote Speaker

  • Timothy Noel (Eindhoven University of Technology), presenting “A Conceptually New Photomicroreactor Design for Energy-efficient Solar Photochemistry

Confirmed speakers include:

  • Andrea Adamo (Zaiput Flow Technologies)
  • Claudio Battilocchio (University of Cambridge)
  • Richard Bourne (University of Leeds, Reaction Chemistry & Engineering Advisory Board)
  • Doris Dallinger (University of Graz)
  • Stevan Djuric (AbbVie)
  • Amanda Evans (California State University Fullerton)
  • Alain Favre-Reguillon (University of Lyon)
  • Daniel Fitzpatrick (University of Cambridge)
  • Antimo Gioiello (University of Perugia)
  • Robert Green (University of Southampton)
  • Heidrun Gruber-Woelfler (Graz University of Technology)
  • Thomas Junkers (Hasselt University)
  • Anita Maguire (University College Cork)
  • Kevin Milburn (University of Bristol)
  • Polona Znidarsic Plazl (University of Ljubljana)
  • Igor Plazl (University of Ljubljana)
  • Dominique Roberge (Lonza Group)
  • Floris Rutjes (Radboud University Nijmegen)
  • Guy Samburski (TEVA)
  • Siegfried Waldvogel (Johannes Gutenburg-University Mainz, Reaction Chemistry & Engineering Advisory Board)
  • Thomas Wirth (Cardiff University)

Early bird discounts are available until 10 January 2017 and the deadline for poster submission is 17 January 2017.

Flow Chemistry Society members save 25% on the cost of registration whilst non-members receive their first year’s membership included in the fee.
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37th International Organic Process Research and Development Conference

We are pleased to announce Organic Process Research& Development – The 37th International Conference and Exhibition, to be held on 6–8 March 2017 at the Westin Pasadena, Pasadena, USA.

On the agenda are discussions of the latest issues relating to synthetic route design, development and optimisation in the parmaceutical, fine chemical and related fields.

Keynote Speaker: Professor Robert Grubbs (CalTech, USA)

Confirmed speakers include:

  • Jean Guy Boiteau (Galderma R&D, France)
  • Peter Hermsen (DSM Chemical Technology R&D, The Netherlands)
  • Scott Hecker (Rempex Pharmaceuticals, USA)
  • Clemens Steuckler (Patheon Austria GmbH & Co KG, Austria)
  • Ben Littler (Vertex Pharmaceuticals, USA)
  • Jade Osei-Tutu (Johnson Matthey Plc, UK)
  • David Rozzell (Provivi, Inc., USA)
  • Scott Savage (Genentech, Inc., USA)
  • Chris Senanayake (Boehringer Ingelheim Pharmaceuticals, Inc., USA)
  • John Studley (Vertex Pharmaceuticals (Europe) Ltd, UK)
  • Rajappa Vaidyanathan (Bristol-Myers Squibb, India)
  • Phillip Wheeler (Materia Inc., USA)

Early bird discount is available if you register before 31 December 2016.

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25th International Symposium: Synthesis in Organic Chemistry – registration now open!

We are delighted to announce that 25th International Symposium: Synthesis in Organic Chemistry will be held in Oxford on 17 – 20 July 2017 – be sure to secure your place today!

Plenary speakers:

  • Michael Krishe, University of Texas at Austin, USA
  • Varinder Agaarwal, University of Bristol, UK

For the full list and details of speakers and conference themes, please visit the event web page.

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21st IUPAC International Conference on Organic Synthesis

We are pleased to announce the 21st International Conference on Organic Synthesis (ICOS 21) which will be held on 11–16 December 2016 at IIT Bombay, Mumbai, India.

This biennial IUPAC event is a platform for the exhibition of new and upcoming topics in the field of organic chemistry.

Returning to India for the first time since ICOS 10 was held at IIS Bangalore in 1994, this conference aims to bring together new ideas across total synthesis, design of new methodologies, flow chemistry, C–H activation, synthetic biology, pharmaceutical chemistry and industrial chemistry.

Register now to attend the meeting alongside the following speakers:

Special Lecture

Professor Goverdhan Mehta, University of Hyderabad, India

Plenary Speakers

  • Janine Cossy, Institute of Chemistry, Biology and Innovation, France
  • Michael Krische, The University of Texas, Austin, USA
  • Dawei Ma, Shanghai Institute of Organic Chemistry, China
  • Klaus Muellen, Max Planck Institute for Polymer Research, Germany
  • Ganesh Pandey, CBMR, India
  • Viresh Rawal, The University of Chicago, USA
  • Chris Senanayake, Boehringer Ingelheim Pharmaceuticals, USA
  • Keisuke Suzuki, Tokyo Institute of Technology, Japan
  • Dean Toste, University of California, USA
  • Herbert Waldmann, Max Planck University of Molecular Physiology, Germany
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2016 AIChE Annual Meeting – RSC stand and speakers

2016 AIChE Annual Meeting

The AIChE Annual Meeting is nearly here! Make sure to visit Stand 33 in the East Lounge, Ballroom Level of the Hilton San Francisco Union Square where the Royal Society of Chemistry and Reaction Chemistry & Engineering Executive Editor Neil Hammond will be on hand to talk about your work:

RSC stand location

In addition, Reaction Chemistry & Engineering Editorial Board Chair Klavs F. Jensen and Scientific Editor Saif F. Khan will be chairing the Reaction Chemistry & Engineering sessions on Tuesday 15 November. Check out the list of confirmed speakers:

Session 375: Reaction Chemistry and Engineering I
Chair: Klavs F. Jensen, MIT, USA – Editorial Board Chair of Reaction Chemistry & Engineering

  • Yang Xiao, Purdue University, USA
  • Vivek V. Ranade, National Chemical Laboratory, Pune, India
  • Sara Jo Taylor, North Carolina State University, USA
  • Paul J. Dauenhauer, University of Minnesota, USA
  • Lukas T. Vömel, RWTH Aachen University, Germany
  • Mark Saeys, Ghent University, Belgium

Session 434: Reaction Chemistry and Engineering II
Chair: Saif A. Khan, NUS, Singapore – Scientific Editor of Reaction Chemistry & Engineering

  • Marcel Schmidt, Technische Universität Berlin, Germany
  • Noor Al-Rifai, University College London, UK
  • Andrew Leung, Imperial College London, UK
  • Andreas Jörke, Anhalt University of Applied Sciences, Germany
  • Eric Grolman, DSM Ahead B.V., Netherlands
  • Irem Sen, Carnegie Mellon University, USA
  • Boris Chubukov, University of Colorado, USA

Also attending from the Reaction Chemistry & Engineering Editorial Board:

  • Mark E. Davis, California Institute of Technology, USA
  • Alexander Katz, University of California, USA
  • Guangsheng Luo, Tsinghua University, China
  • Dionision G Vlachos, University of Delaware, USA
  • and special thanks to Advisory Board member Ryan Hartman, New York University, USA, for organising these sessions!

See the full Technical Program for the meeting. Klavs, Saif and Neil look forward to welcoming you to San Francisco.

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‘Robo-chemist’ optimises reactions in one day

Reaction Chemistry & Engineering Chair Klavs Jensen and colleague Steve Buchwald have developed an intelligent automated reactor that drastically cuts the time it takes to optimise cross-coupling reactions.

Their automated flow reactor that can respond to the results of experiments and determine the optimum conditions for catalytic reactions within a single day.

suzuki miyaura optimisation

RCE Advisory Board member Ryan Hartman highly praises the research as a ‘vital contribution that advances both synthetic chemistry and chemical engineering’ in Chemistry World.

Check out the full story by Jamie Durrani here.


This article is open access

B J Reizman et al, React. Chem. Eng., 2016, DOI: 10.1039/C6RE00153J

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Batch and flow: united at last

Batch and flow chemistry can finally be carried out together on the same system!

Reaction Chemistry & Engineering Editorial Board member Steve Ley and colleague Daniel Fitzpatrick at the University of Cambridge have developed an automated reactor that can carry out both batch and flow processes, allowing for greater automation of multi-step synthesis.

Read the full story in Chemistry World.

This article is free to access until 25 November 2016

D E Fitzpatrick and S V Ley, React. Chem. Eng., 2016, DOI: 10.1039/C6RE00160B

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2016 AIChE Annual Meeting

The AIChE Annual Meeting is the premier educational forum for chemical engineers interested in innovation and professional growth. Academic and industry experts will cover a wide range of topics relevant to cutting-edge research, new technologies, and emerging growth areas in chemical engineering.

With the meeting fast-approaching, we are delighted to announce that Reaction Chemistry & Engineering will be running two sessions on Tuesday, 15 November:

Session 375: Reaction Chemistry and Engineering I
Chair: Klavs F. Jensen, Chair of Reaction Chemistry & Engineering

Session 434: Reaction Chemistry and Engineering II
Chair: Saif A. Khan, Scientific Editor for Reaction Chemistry & Engineering

These sessions will focus on the following topics:

  • Reaction mechanism and kinetics
  • Reaction analysis and monitoring
  • Catalytic reactions
  • Multiphase and new reactor technology

Check out the full Technical Program for the meeting and we look forward to seeing you in San Francisco!

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