Focus: Studying biology using chemical tools

Graphical abstract: P450BM3 (CYP102A1): connecting the dotsChemical techniques are critical for studying and manipulating biological systems. We’ve published a great selection of reviews at the interface of chemistry and biology, including these recent articles:

Mass spectrometry based tools to investigate protein–ligand interactions for drug discovery
Kamila J. Pacholarz, Rachel A. Garlish, Richard J. Taylor and Perdita E. Barran
Chem. Soc. Rev., 2012, DOI: 10.1039/C2CS35035A

Diversity-oriented synthesis: producing chemical tools for dissecting biology
Cornelius J. O’ Connor, Henning S. G. Beckmann and David R. Spring
Chem. Soc. Rev., 2012, DOI: 10.1039/C2CS35023H

Assays for human telomerase activity: progress and prospects
Xiaoming Zhou and Da Xing
Chem. Soc. Rev., 2012, DOI: 10.1039/C2CS35045A

Mass spectrometry-based proteomics: existing capabilities and future directions
Thomas E. Angel, Uma K. Aryal, Shawna M. Hengel, Erin S. Baker, Ryan T. Kelly, Errol W. Robinson and Richard D. Smith
Chem. Soc. Rev., 2012,41, 3912-3928

Autophagy-regulating small molecules and their therapeutic applications
Kyung-Hwa Baek, Jihye Park and Injae Shin
Chem. Soc. Rev., 2012,41, 3245-3263

Probing the kinome in real time with fluorescent peptides
Juan A. González-Vera
Chem. Soc. Rev., 2012,41, 1652-1664

Upconversion nanophosphors for small-animal imaging
Jing Zhou, Zhuang Liu and Fuyou Li
Chem. Soc. Rev., 2012,41, 1323-1349

Do you have an idea for a review? Let us know >

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