Rapid curing of PDMS for microfluidic applications

Adrian O’Neill, Jeffrey Soo Hoo and Glenn Walker present a new procedure for the curing of PDMS for microfluidic applications.

Adrian O’Neill, Jeffrey Soo Hoo and Glenn Walker
Joint Department of Biomedical Engineering, University of North Carolina-Chapel Hill and North Carolina State University

Why is this useful?


A new curing procedure is presented to expedite poly(dimethylsiloxane) (PDMS) microfluidic device fabrication. For microfluidic applications, PDMS is typically cured over a master in a plastic Petri dish at 80ºC for 2.5 hours. The curing temperature is limited by the maximum temperature a plastic Petri dish can withstand without warping. Dow Corning Sylgard 184 PDMS can be cured over a range of times and temperatures, spanning ~48 hours at room temperature to 10 minutes at 150ºC.  We present an alternate curing method, using an aluminium foil dish, that reduces the curing time from 2.5 hours to 10 minutes.

What do I need?


  • Aluminium foil, 0.001 inch thickness or greater
  • 90mm diameter crystallization dish (Pyrex 90 x 50mm)
  • PDMS (Dow Corning Sylgard 184)
  • Hotplate (Barnstead 721A digital hotplate)

What do I do?


1. Cut a 4.5 inch diameter circle out of aluminium foil, being careful not to wrinkle the foil. Wrinkles may tilt the master causing the thickness of the PDMS mould to vary from one side of the design to the other.

Figure 1.

2. Form the foil over the bottom of the 90mm crystallization dish, as shown in Figure 1.

Figure 2.

3. After gently removing the foil, place the master in the foil dish and put the dish on a room temperature hotplate.

4. Mix the PDMS according to the manufacturer’s procedure [1].

Figure 3.

5. Pour the desired amount of PDMS over the master, as shown in Figure 2.

6. Set the hotplate temperature to 150ºC. Once at 150ºC, cure the PDMS for 10 minutes.

Figure 4.

7. Remove the foil dish from the hotplate and allow it to cool to room temperature.

8. Gently peel or cut the aluminium foil from the master and cut away any excess PDMS (Figure 3).

9. Finally, peel the PDMS mould from the master (Figure 4).

References


[1] Dow Corning Product Information, “Information about Dow Corning® brand Silicone Encapsulants,” 2005.

Digg This
Reddit This
Stumble Now!
Share on Facebook
Bookmark this on Delicious
Share on LinkedIn
Bookmark this on Technorati
Post on Twitter
Google Buzz (aka. Google Reader)

20 Responses to “Rapid curing of PDMS for microfluidic applications”

  1. [...] Engineered and Molecular Systems, 319-322. [5] Adrian O’Neill, Jeffrey Soo Hoo and Glenn Walker, Rapid curing of PDMS for microfluidic applications, Chips & Tips, Lab on a Chip, 23 October [...]

    (Report comment)

  2. [...] [1] A. O’Neill, J. Soo Hoo and G. Walker, Rapid curing of PDMS for microfluidic applications, Chips and Tips from Lab on a Chip, 23 October [...]

    (Report comment)

  3. The movers and packers in Bangalore offer all the solutions of Packers and movers like appearance solutions, movers, Running Solutions, Unloading Solutions, Transportation, and rearrangements’ etc.

    Expert 5 Packers and Movers Delhi go to
    http://www.expert5th.in/packers-and-movers-delhi/

    Expert 5 Packers and Movers Gurgaon go to
    http://www.expert5th.in/packers-and-movers-gurgaon/

    Expert 5 Packers and Movers Chennai go to
    http://www.expert5th.in/packers-and-movers-chennai/

    Top 6 Packers and Movers Pune go to
    http://packersmoverspune.top3rd.in/

    Expert 5 Packers and Movers Hyderabad go to
    http://www.expert5th.in/packers-and-movers-hyderabad/

    Expert 5 Packers and Movers Bangalore go to
    http://www.expert5th.in/packers-and-movers-bangalore/

    Expert 5 Packers and Movers Mumbai go to
    http://www.expert5th.in/packers-and-movers-mumbai/

    (Report comment)

  4. expert modifying, company shifting, and in some cases designed for international shifting
    Packers and Movers in Hyderabad @ http://www.expert5th.in/packers-and-movers-hyderabad/
    Packers and Movers in Mumbai @ http://www.expert5th.in/packers-and-movers-mumbai/
    Packers and Movers in Pune @ http://packersmoverspune.top3rd.in/

    (Report comment)

  5. However determining on the best movers is usually a essential issue.
    Packers and Movers in Bangalore @ http://www.expert5th.in/packers-and-movers-bangalore/
    Packers and Movers in Delhi @ http://www.expert5th.in/packers-and-movers-delhi/
    Packers and Movers Gurgaon @ http://www.expert5th.in/packers-and-movers-gurgaon/

    (Report comment)

  6. An occasion you had to keep in mind once you choose the movers can be shifting assistance need to be the one that definitely caters your near close relatives affiliates
    Packers and Movers Chennai @ http://www.expert5th.in/packers-and-movers-chennai/
    Packers and Movers Noida @ http://www.expert5th.in/packers-and-movers-noida/

    (Report comment)

  7. Fill the items within along with set up these people efficiently avoiding arriving from damage.
    Movers and Packers in Mumbai
    Movers and Packers in Hyderabad

    (Report comment)

  8. Making a shifting cost-effective scenario can certainly reduce money as well as time too.
    Packers and Movers in Pune
    Packers and Movers in Bangalore

    (Report comment)

  9. Packers and Movers Mumbai
    Packers and Movers in Mumbai
    Movers and Packers Pune
    Movers and Packers in Pune
    Speak to the actual embassy of the location region, and have just about all needed appropriate details relating to the new house purchase, like: visa qualification, tailor made regulations, driving a car enable prerequisites, health care insurance information, proposed inoculations, etc’.
    For more information please visit:-http://list5th.in/packers-and-movers-mumbai/

    (Report comment)

  10. Packers and Movers Pune
    Packers and Movers in Pune
    Movers and Packers Mumbai
    Movers and Packers in Mumbai
    Lifetime is basically unknown so you under no circumstances know what’s going to happen in the particular adjust. Consequently, you should get assist linked to specialists with regards to finishing the place using finesse.
    For more information please visit:-http://list5th.in/packers-and-movers-pune/

    (Report comment)

  11. Local packer’s movers regarding India will help you inside a lot more convenient way. You may also know about these people greater for their products and services and dependability.

    Packers and Movers Faridabad
    Movers and Packers in Faridabad
    Packers and Movers in Faridabad
    Movers and Packers Faridabad

    (Report comment)

  12. well as statements and affirmations may easily typically discovered people with your personal individual retailers related to add-on to help you coaching someone in addition to gentleman scenario impressive can quickly typically probably.
    Packers and Movers Navi Mumbai
    Packers and Movers in Navi Mumbai
    Movers and Packers Navi Mumbai
    Movers and Packers in Navi Mumbai
    Having time-frame ample commonly by using venture in addition to must be top quality. Authenticate an outstanding feminine in addition to impressive baby crucial durable issues an established substantially in addition to health problems in addition to affirms in addition to health issues included in
    http://top3th.co.in/packers-and-movers-thane/

    (Report comment)

  13. Remarkable packers basically movers in only might stop a great deal of do the job basically provide hassle-free basically much more than joked could be along with fun. For that reason

    Packers and Movers Pune

    Packers and Movers Bangalore

    Packers and Movers Gurgaon

    (Report comment)

  14. Thanks for sharing your info. I really appreciate your efforts and I will be waiting for your further write
    Packers and Movers in Hyderabad
    Packers and Movers in Bangalore
    Packers and Movers in Mumbai

    (Report comment)

  15. Take whereby situation which will be advantageous in case you are. While undertaking your entire current hauling and in some cases moving by using

    Packers and Movers

    Packers and Movers Mumbai

    Packers and Movers Delhi

    Packers and Movers Noida

    (Report comment)

  16. SEO EXPERT says:

    The next surprising thing for your growing better life is that now you can buy real Buy Instagram Likes followers for your personal Buy Instagram Likes account.

    (Report comment)

Leave a Reply