Archive for August, 2012

Top ten most accessed articles in July

This month sees the following articles in PPS that are in the top ten most accessed:-

Heteroaromatic Donors in Donor-Acceptor-Donor Based Fluorophores Facilitate Zinc Ion Sensing and Cell Imaging
Sivaramapanicker Sreejith, Kizhumuri P. Divya, Purushothaman Jayamurthy, Jomon Mathew, V. N. Anupama, Divya Susan Philips, Palappuravan Anees and Ayyappanpillai Ajayaghosh
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25110H, Paper

Structural effects on the pH-dependent fluorescence of naphthalenic derivatives and consequences for sensing/switching
Shuai Zheng, P. L. Mark Lynch, Terence E. Rice, Thomas S. Moody, H. Q. Nimal Gunaratne and A. Prasanna de Silva
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25069A, Paper

Photoswitchable fluorescent diarylethene derivatives with short alkyl chain substituents
Yuta Takagi, Tomohiro Kunishi, Tetsuro Katayama, Yukihide Ishibashi, Hiroshi Miyasaka, Masakazu Morimoto and Masahiro Irie
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25078K, Paper

History of phototherapy in dermatology
Herbert Hönigsmann
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25120E, Perspective

Fluorescence photoswitching and photoreversible two-way energy transfer in a photochrome-fluorophore dyad
Karima Ouhenia-Ouadahi, Rémi Métivier, Stéphane Maisonneuve, Aurélie Jacquart, Juan Xie, Anne Léaustic, Pei Yu and Keitaro Nakatani
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25129A, Paper

On the genesis of heterogeneous photocatalysis: a brief historical perspective in the period 1910 to the mid-1980s
N. Serpone, A. V. Emeline, S. Horikoshi, V. N. Kuznetsov and V. K. Ryabchuk
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25026H

Engineered photoreceptors as novel optogenetic tools
Andreas Möglich and Keith Moffat
Photochem. Photobiol. Sci., 2010,9, 1286-1300, DOI: 10.1039/C0PP00167H, Perspective

Remarkable fluorescence enhancement of benzo[g]chromen-2-ones induced by hydrogen-bonding interactions with protic solvents
Atsushi Kobayashi, Kazuyuki Takehira, Toshitada Yoshihara, Seiichi Uchiyama and Seiji Tobita
Photochem. Photobiol. Sci., 2012,11, 1368-1376, DOI: 10.1039/C2PP25055A, Paper

Dynamics of ion-regulated photoinduced electron transfer in BODIPY-BAPTA conjugates
Pinar Batat, Guillaume Vives, Robin Bofinger, Ren-Wei Chang, Brice Kauffmann, Reiko Oda, Gediminas Jonusauskas and Nathan D. McClenaghan
Photochem. Photobiol. Sci., 2012, Advance Article, DOI: 10.1039/C2PP25130B, Paper

2-Hydroxyphenacyl ester: a new photoremovable protecting group
Bokolombe Pitchou Ngoy, Peter Šebej, Tomáš Šolomek, Bum Hee Lim, Tomáš Pastierik, Bong Ser Park, Richard S. Givens, Dominik Heger and Petr Klán
Photochem. Photobiol. Sci., 2012,11, 1465-1475, DOI: 10.1039/C2PP25133G, Paper

Why not take a look at the articles today and blog your thoughts and comments below.

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PPS Issue 9 is now online

PPS Issue 9 front coverPPS Issue 9 is online now; you can read the full issue here.  The front cover features a communication from Santi Nonell, Cristina Flors and their co-workers.  This study demonstrates for the first time that intracellular singlet oxygen is sufficient to kill bacteria. 

The team from Barcelona, Madrid and Edinburgh expressed, in E. Coli, TagRFP, a fluorescent protein capable of photosensitizing the production of singlet oxygen.  Subsequent exposure to green light induced bacterial cell death in a light-dose dependent manner.

Interested in knowing more? Read the full article – free for 6 weeks!

A genetically-encoded photosensitiser demonstrates killing of bacteria by purely endogenous singlet oxygen
Rubén Ruiz-González, John H. White, Montserrat Agut, Santi Nonell and Cristina Flors
Photochem. Photobiol. Sci., 2012, 11, 1411-1413

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Cleaning hands with light

An E. coli outbreak in 2011 originating from a German sprout farm caused 45 deaths and a total of nearly 4000 cases in Germany alone. Image credit: iStockphoto

A quick way to kill methicillin resistant Staphylococcus aureus (MRSA) and other pathogens using a photosensitiser and visible light can be used to clean hands, say scientists in Germany. 

The over-use of antibiotics has allowed many pathogens to develop resistances. The most well known is MRSA, which has now become a global problem, particularly in hospitals. Researchers are therefore constantly on the lookout for new ways to combat these microbes.

One way to kill bacteria that doesn’t involve drugs is antimicrobial photodynamic therapy (APDT). PDT is a well-known technique for the targeted destruction of cells, typically used for tumour therapy. Light is used to activate a photosensitiser, creating reactive oxygen species that kill the surrounding cells. It can be applied selectively to bacteria when a positively charged photosensitiser is able to attach to the bacteria’s negatively charged cell wall.

Read the full article in Chemistry World

Link to journal article
Dirty hands: Photodynamic killing of human pathogens like EHEC, MRSA and Candida within seconds
A Eichner et al
Photochem. Photobiol. Sci., 2012, DOI: 10.1039/c2pp25164g

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