Issue 4 of Organic & Biomolecular Chemistry is now online

Issue 4 of Organic & Biomolecular Chemistry is now online; find it HERE

This rather green and leafy cover image is courtesy of Kazuya Kikuchi and co-workers at Osaka University who have developed a new mechanism for a reversible dual “OFF–ON–OFF” pH sensor with the influence from a suitably located carboxylic acid group.

pH Induced dual “OFF–ON–OFF” switch: influence of a suitably placed carboxylic acid
Kalyan K. Sadhu, Shin Mizukami, Akimasa Yoshimura and Kazuya Kikuchi
DOI: 10.1039/C2OB26630J

Highlighted on the inside cover of this issue is the work of J. Carlos Menéndez and colleagues who have developed an efficient method for the synthesis of trans-2-aryl-4-arylamino-tetrahydroquinolines from 3,5-disubstituted anilines, vinyl ethers and aromatic aldehydes.

Diastereoselective, multicomponent access to trans-2-aryl-4-arylamino-1,2,3,4-tetrahydroquinolines via an AA′BC sequential four-component reaction and their application to 2-arylquinoline synthesis

Pascual Ribelles, Vellaisamy Sridharan, Mercedes Villacampa, Mª Teresa Ramos and J. Carlos Menéndez
DOI: 10.1039/C2OB26754C

Both articles are free to access for the next 6 weeks

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