Scientists in Canada have reported the anti-leukaemia activity of four new prodigiosin analogues in vitro in a cancer cell line and in vivo in a zebrafish model. Prodigiosin is the parent member of a family of tripyrrolic natural products isolated from bacteria.
Investigations regarding the utility of prodigiosenes to treat leukemia
Deborah A. Smithen, A. Michael Forrester, Dale P. Corkery, Graham Dellaire, Julie Colpitts, Sherri A. McFarland, Jason N. Berman and Alison Thompson
Org. Biomol. Chem., DOI: 10.1039/C2OB26535D
