Can LTA (lipoteichoic acids) be considered to be “the (endo)toxin of Gram-positive bacteria”?
Richard R. Schmidt, Ulrich Zahringer and their groups have become one of the leading teams in LTAs research. They have synthesised different types of LTAs and tested their biological activities against different receptors of the innate immune system.
They summarise part of their results and those of different groups working on the area in this comprehensive OBC review. Download it now.
Chemical synthesis of bacterial lipoteichoic acids: An insight on its biological significance
Richard R. Schmidt, Christian M. Pedersen, Yan Qiao and Ulrich Zähringer
Org. Biomol. Chem., 2011, 9, 2040-2052
DOI: 10.1039/C0OB00794C, Perspective
