US-China Workshop on Analytical Chemistry – stronger together

Last week I attended a US-China Workshop at Purdue University, US, which brought together some of the brightest minds in analytical science from these two countries, to exchange ideas and provide suggestions for the development of  the subject.

Topics for discussion included how the community can help to raise the profile of publications in analytical science, research trends, infrastructure and instrumentation and the status of analytical post-graduate education.

A major theme was collaboration, and it was recognised that enabling US scientisits to visit and work in China, and vice versa, is incredibly important. There are a huge number of Chinese students looking to carry out post-graduate study in the US and Europe, however this is currently a one-way street.

To support closer ties, it was also recognised that not all the high profile journals have Chinese representation on their Editorial and Advisory Boards. Whilst this an area where the RSC is very proactive (and will aim to continue strengthening our links),  it is hoped that other publishers will also follow suit. This year, Analyst has seen significant growth in the number of papers coming from China. As well as the growth in the subject, is also partly due to the appointment of Professor Xinrong Zhang at Tsinghua University, Beijing as Associate Editor for Asia.

One thing is clear, whilst there is concern that analytical chemistry doesn’t always get the billing it deserves in  the US, this is certainly not the case in China. The growth in investment in analytical departments in China has been exponential over the past few years, and this is something that we are certainly beginning to see reflected in the quantity, and quality, of the  research being done.

With open and informative workshops such as these, it will be fascinating to follow the outcomes and developments of this collaboration. However a big first step has been taken, recognising that by working together, the worlds two superpowers of analytical science can really ensure the future of the subject continues to be exciting.

Read the Analyst themed issue on ‘Highlighting analytical science in China’.

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Looking cancer in the eye

Scientists from the UK and Japan have discovered a way to identify pre-cancerous stem cells in the eye using absorbance spectra data.

Characterising cells in the cornea could prevent recurring cancer

Cancerous tumours in the cornea can cause loss of vision and, if left untreated, can become aggressive. Treatment is to cut out the cancerous cells but there is often a high chance of the disease recurring. Identifying normal tissue that has the potential to become cancerous prior to treatment could ensure complete removal and lower the risk of cancer reoccurring after treatment.

Despite decades of intense research, there are currently very few proficient stem cell biomarkers for the cornea. Now a team lead by Frank Martin at the University of Lancaster, UK, have used the sensitive and high-throughput approach of synchrotron-based Fourier-transform infrared microspectroscopy to create an image map of cornea samples to recognise differences between cell types and highlight prospective biomarkers.

To read Jennifer Newton’s full Highlights in Chemical Biology article, please click here: Looking cancer in the eye

Evidence for a stem-cell lineage in corneal squamous cell carcinoma using synchrotron-based Fourier-transform infrared microspectroscopy and multivariate analysis
Jemma G. Kelly, Takahiro Nakamura, Shigeru Kinoshita, Nigel J. Fullwood and Francis L. Martin, Analyst, 2010
DOI:
10.1039/c0an00507j

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Radicals in water

Terephthalate as a probe for photochemically generated hydroxyl radical

Terephthalate picks up an OH radical to form fluorescent hydroxyterephthalate

Sarah E. Page, William A. Arnold and Kristopher McNeill, J. Environ. Monit., 2010, 12, 1658
DOI: 10.1039/c0em00160k

A sensitive probe to monitor hydroxyl radicals in water has been developed by a team of Swiss and US scientists.
Current hydroxyl radical probes, such as benzoic acid, often have limited sensitivity, require long irradiation times or high concentrations of the probe, which can affect the sample.  Now Kristopher McNeill at the Swiss Federal Institute of Technology (ETH) in Zurich and colleagues at the University of Minnesota in Minneapolis have discovered that terephthalate is a more sensitive probe for hydroxyl radicals in aquatic environments.

Read Rachel Cooper’s full news article at Highlights in Chemical Technology.

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Top 10 most-read Analyst Articles

The latest top ten most downloaded Analyst articles

Read the most-read papers of August 2010 here:

Thick-film textile-based amperometric sensors and biosensors
Yang-Li Yang, Min-Chieh Chuang, Shyh-Liang Lou and Joseph Wang, Analyst, 2010, 135, 1230
DOI:
10.1039/b926339j

Upconversion nanoparticles in biological labeling, imaging, and therapy
Feng Wang, Debapriya Banerjee, Yongsheng Liu, Xueyuan Chen, Xiaogang Liu, Analyst, 2010, 135, 1839
DOI:
10.1039/c0an00144a

Instantaneous chemical profiles of banknotes by ambient mass spectrometry
Livia S. Eberlin, Renato Haddad, Ramon C. Sarabia Neto, Ricardo G. Cosso, Denison R. J. Maia, Adriano O. Maldaner, Jorge Jardim Zacca, Gustavo B. Sanvido, Wanderson Romão, Boniek G. Vaz, Demian R. Ifa, Allison Dill, R. Graham Cooks and Marcos N. Eberlin, Analyst, 2010
DOI:
10.1039/c0an00243g

Bioactive paper dipstick sensors for acetylcholinesterase inhibitors based on sol–gel/enzyme/gold nanoparticle composites
Roger E. Luckham and John D. Brennan, Analyst, 2010, 135, 2028
DOI:
10.1039/c0an00283f

Sunil K. Arya, Ganna Chornokur, Manju Venugopal and Shekhar Bhansali, Analyst, 2010, 135, 1941-1946
DOI:
10.1039/C0AN00242A
 
Chuda Raj Lohani, Joung-Min Kim, So-Young Chung, Juyoung Yoon and Keun-Hyeung Lee, Analyst, 2010, 135, 2079-2084
DOI:
10.1039/C0AN00059K
 
Ting Qiu, Dan Zhao, Guohua Zhou, Yuan Liang, Zhike He, Zhihong Liu, Xiaoniu Peng and Li Zhou, Analyst, 2010, 135, 2394-2399
DOI:
10.1039/C0AN00254B
 
Kangwon Lee, Laura K. Povlich and Jinsang Kim, Analyst, 2010, 135, 2179-2189
DOI:
10.1039/C0AN00239A
 
Carol E. Parker, Terry W. Pearson, N. Leigh Anderson and Christoph H. Borchers, Analyst, 2010, 135, 1830-1838
DOI:
10.1039/C0AN00105H
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Nominations for 2011 RSC Prizes and Awards now open

Nominate a colleague...or yourself!

The RSC currently presents around 60 prestigious Prizes and Awards annually to scientists in all the main chemical science disciplines allowing for the greatest range of scientists to be recognised for their work; individuals, teams and organisations working across the globe.

There are nine categories of awards including specific categories for Industry and Education so whether you work in business, industry, research or education recognition is open to everyone.

Our Prizes and Awards represent the dedication and outstanding achievements in the chemical sciences and are a platform to showcase inspiring science to gain the recognition deserved.

Do you know someone who has made a significant contribution to advancing the chemical sciences?

View our full list of Prizes and Awards and use the online system to nominate yourself or colleagues.

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A sunny outlook for vitamin D detection

Vitamin D and its metabolites have an important role in our body's health

US researchers have developed a nanotechnology-based test to detect the important vitamin D metabolite calcitriol, the deficiency of which is an indicator of kidney failure.

Competitive surface-enhanced Raman scattering assay for the 1,25-dihydroxy metabolite of vitamin D3

Eric J. Dufek, Brian Ehlert, Michael C. Granger, Tanya M. Sandrock, Samuel L. Legge, Mark G. Herrmann, A. Wayne Meikle and Marc D. Porter, Analyst, 2010
DOI: 10.1039/c0an00354a

Marc Porter and colleagues at the University of Utah in Salt Lake City have developed a test based on the use of surface enhanced Raman scattering (SERS) combined with gold nanoparticles. This new technique requires a much smaller sample volume and has no radioactive waste compared to previous approaches.

“This paper is a very nice example of the use of SERS for the detection of metabolites in clinically relevant samples,” comments Karen Faulds, at the Centre of Molecular Nanometrology in Strathclyde, UK.

Read Rebecca Brodie’s news story at Highlights in Chemical Biology or peruse the article in full in Analyst.

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Most read Analyst articles

The latest most downloaded Analyst articles

Read the most-read papers of July 2010 here:

Instantaneous chemical profiles of banknotes by ambient mass spectrometry
Livia S. Eberlin, Renato Haddad, Ramon C. Sarabia Neto, Ricardo G. Cosso, Denison R. J. Maia, Adriano O. Maldaner, Jorge Jardim Zacca, Gustavo B. Sanvido, Wanderson Romão, Boniek G. Vaz, Demian R. Ifa, Allison Dill, R. Graham Cooks and Marcos N. Eberlin, Analyst, 2010
DOI:
10.1039/c0an00243g

Thick-film textile-based amperometric sensors and biosensors
Yang-Li Yang, Min-Chieh Chuang, Shyh-Liang Lou and Joseph Wang, Analyst, 2010, 135, 1230
DOI:
10.1039/b926339j

Analytical methods to assess nanoparticle toxicity
Bryce J. Marquis, Sara A. Love, Katherine L. Braun and Christy L. Haynes, Analyst, 2009, 134, 425
DOI:
10.1039/b818082b 

Upconversion nanoparticles in biological labeling, imaging, and therapy
Feng Wang, Debapriya Banerjee, Yongsheng Liu, Xueyuan Chen, Xiaogang Liu, Analyst, 2010, 135, 1839
DOI:
10.1039/c0an00144a

Analytical strategies for detecting nanoparticle–protein interactions
Liwen Li, Qingxin Mu, Bin Zhang and Bing Yan, Analyst, 2010, 135, 1519
DOI:
10.1039/c0an00075b

Bioactive paper dipstick sensors for acetylcholinesterase inhibitors based on sol–gel/enzyme/gold nanoparticle composites
Roger E. Luckham and John D. Brennan, Analyst, 2010, 135, 2028
DOI:
10.1039/c0an00283f

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Mass spec – a vital tool

“Graham Cooks, from Purdue University, arguably a mass spectrometry genius of our time…”

Head over to the Chemistry World blog to see Mike Brown’s report from the 3rd EuCheMS Chemistry Conference in Nürnberg, Germany, where one of the speakers was Analyst Editorial Board member Graham Cooks.

Read the whole story to find out what Mike heard about using mass spec to study fingerprints and foul breath!

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Electrochemical sensor for toxic compound

Carbon-modified zinc nanorod array has impoved sensing ability

Chinese scientists have developed a highly efficient and chemically stable hydrazine sensor using carbon modified zinc oxide nanorods.  Hydrazine is highly neurotoxic and carcinogenic and can cause severe damage to the liver, lungs and kidneys.  It is used extensively in industry, and for safety considerations a reliable hydrazine sensor is highly desirable.

To find out why this new sensor is special, read Jacob Bush’s news article at Highlights in Chemical Science or access the full article via Dalton Transactions:

C@ZnO nanorod array-based hydrazine electrochemical sensor with improved sensitivity and stability
Jinping Liu, Yuanyuan Li, Jian Jiang and Xintang Huang
Dalton Trans., 2010, Advance Article
DOI: 10.1039/C0DT00258E

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Analyst Editorial Board Chair wins RSC award

I am delighted to say that Professor Paul Bohn, Arthur J. Schmitt Professor of Chemical and Biomolecular Engineering, Professor of Chemistry and Biochemistry at Notre Dame University, US and Chair of the Analyst Editorial Board has been awarded the 2010 Theophilus Redwood Award. This is in recognition of the breadth and impact of his contribution to analytical science in the areas of microfludic and nanoscale chemical sensing.

Paul joined the Analyst Editorial team in 2007, and served as the Editor for the Americas for three years, before being appointed Chair at the beginning of 2010.

The Theophilus Redwood Award is given to a leading analytical scientist who is also an outstanding communicator, and is awarded by the RSC Analytical Divison. It is sponsored by the Analytical Chemistry Trust Fund.

Read a selection of Paul’s work published in Analyst:

High sensitivity hydrogen sensing with Pt-decorated porous gallium nitride prepared by metal-assisted electroless etching
Barrett K. Duan and Paul W. Bohn
Analyst, 2010, 135, 902-907, http://dx.doi.org/10.1039/B926182F

Enzymatic activity of surface-immobilized horseradish peroxidase confined to micrometer- to nanometer-scale structures in nanocapillary array membranes  Zhen Wang, Travis L. King, Sean P. Branagan and Paul W. Bohn
Analyst, 2009, 134, 851-859, http://dx.doi.org/10.1039/B815590A

Analytical sciences – an endless horizon 
Analyst, 2010, 135, 439-440, http://dx.doi.org/10.1039/C002392M

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