Author Archive

Tattoo sensor

A sensor to be injected into the skin just like a tattoo that measures sodium concentrations in the blood has been developed by Heather Clark from Northeastern University and colleagues.

The sensor falls off after seven days, like a non-permanent tattoo.

To find out more about how plastic nanobeads and fluorescence have been used in this way, read Fran Burgoyne’s news article at Highlights in Chemical Biology or click below to access the Integrative Biology article in full for free.

In vivo sodium concentration continuously monitored with fluorescent sensors
J. Matthew Dubach, Edward Lim, Ning Zhang, Kevin P. Francis and Heather Clark, Integr. Biol., 2011
DOI: 10.1039/c0ib00020e

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Probing stomach cancer

Gastric cancer is one of the leading causes of cancer-associated death in the world.

Zhiwei Huang and colleagues at the National University of Singapore and National University Hospital have developed a technique that could be used to distinguish between benign and malignant ulcers in the stomach.
The method employs an endoscopy probe that analyses tissue using Raman spectroscopy.

Want to know more?

Read Harriet Brewerton’s news article at Highlights in Chemical Biology or access the full article using the link below:

Raman endoscopy for in vivo differentiation between benign and malignant ulcers in the stomach
Mads Sylvest Bergholt, Wei Zheng, Kan Lin, Khek Yu Ho, Ming Teh, Khay Guan Yeoh, Jimmy Bok Yan So and Zhiwei Huang
Analyst, 2010, 135, 3162
DOI: 10.1039/c0an00336k

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Mimicking the human nose

The 'nose' uses differential sensing, a form of molecular recognition, to recognise subtle structural differences between the molecules.

Stefan Matile and colleagues from the University of Geneva have created a system that mimics the way the human nose recognises scents.

Read Will Dennis’ news story at Highlights in Chemical Technology and read the full article in Chemical Science.

Pattern generation with synthetic sensing systems in lipid bilayer membranes
Toshihide Takeuchi, Javier Montenegro, Andreas Hennig and Stefan Matile, Chem. Sci., 2010
DOI: 10.1039/c0sc00386g

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Chemical residues: rapid, simple, quantitative screening

Fast extraction and dilution flow injection mass spectrometry (FED-FI-MS)

Sergio C. Nanita proposes an improved, simple and rapid method based on flow injection MS/MS for quantitative multiresidue screening in complex matrices.

High-throughput chemical residue analysis by fast extraction and dilution flow injection mass spectrometry
Sergio C. Nanita
Analyst, 2011, Advance Article
DOI: 10.1039/C0AN00720J, Communication

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Analyst Board members awarded at FACSS

Prof. Boris Mizaikoff, University of Ulm

Prof. Christy Haynes, University of Minnesota

Two Analyst Board members were honoured at FACSS 2010, held in Raleigh, USA last month.

Boris Mizaikoff, Analyst Associate Editor for Europe, was recipient of the 2010 Craver Award.  The Coblenz Society Clara Craver Award recognises the efforts of young scientists who have made significant contributions in applied analytical vibrational spectroscopy.

Christy Haynes, Analyst Advisory Board member, received the Arthur F. Findeis Award from the ACS Division of Analytical Chemistry, which recognises and encourages outstanding contributions to the fields of analytical chemistry by a young scientist.

Congratulations to you both!

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Norharmane: Old yet highly selective dual channel sensor

Arabinda Mallick and colleagues describe a new fully reversible dual channel optical sensor with extraordinary selectivity for fluoride and hydrogen sulfate ions.  Read the communication in full:

Norharmane: Old yet highly selective dual channel ratiometric fluoride and hydrogen sulfate ion sensor
Arabinda Mallick, Tetsuro Katayama, Yukihide Ishibasi, Masakazu Yasuda and Hiroshi Miyasaka
Analyst, 2011, Advance Article
DOI: 10.1039/C0AN00650E

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Most-read Analyst articles in September

The most popular Analyst articles in September

Read five of the most-read papers in September 2010 here:

Thick-film textile-based amperometric sensors and biosensors
Yang-Li Yang, Min-Chieh Chuang, Shyh-Liang Lou and Joseph Wang, Analyst, 2010, 135, 1230
DOI: 10.1039/b926339j

Instantaneous chemical profiles of banknotes by ambient mass spectrometry
Livia S. Eberlin, Renato Haddad, Ramon C. Sarabia Neto, Ricardo G. Cosso, Denison R. J. Maia, Adriano O. Maldaner, Jorge Jardim Zacca, Gustavo B. Sanvido, Wanderson Romão, Boniek G. Vaz, Demian R. Ifa, Allison Dill, R. Graham Cooks and Marcos N. Eberlin, Analyst, 2010
DOI: 10.1039/c0an00243g

Kangwon Lee, Laura K. Povlich and Jinsang Kim, Analyst, 2010, 135, 2179-2189
DOI: 10.1039/C0AN00239A
 
Cuiping Han and Haibing Li Analyst, 2010, 135, 583-588
DOI: 10.1039/B923424A
 
Patrick J. Roach, Julia Laskin and Alexander Laskin, Analyst, 2010, 135, 2233-2236
DOI: 10.1039/C0AN00312C
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Sensitive sensors: NPZ in pharmaceuticals

Hot off the press: Eman Frag and colleagues describe the development of screen-printed (SPE) and carbon paste (CPE) sensors for the rapid and sensitive quantification of naphazoline hydrochloride (NPZ) in pharmaceutical formulations.

Construction and performance characterization of screen printed and carbon paste ion selective electrodes for potentiometric determination of naphazoline hydrochloride in pharmaceutical preparations
Eman Y. Z. Frag, Gehad G. Mohamed, F. A. Nour El-Dien and Marwa E. Mohamed
Analyst, 2011, Advance Article
DOI: 10.1039/C0AN00343C

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Glowing glucose tracker

H Shibata et al, Proc. Natl. Acad. Sci. USA, 2010, DOI: 10.1073/pnas.1006911107

Japanese researchers have developed microscale beads that visibly glow under the skin in response to blood glucose levels, signalling a potential end to repeated fingertip prick blood tests for diabetics needing to monitor their glucose levels.

Read the full story at Chemistry World.

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Looking cancer in the eye

Scientists from the UK and Japan have discovered a way to identify pre-cancerous stem cells in the eye using absorbance spectra data.

Characterising cells in the cornea could prevent recurring cancer

Cancerous tumours in the cornea can cause loss of vision and, if left untreated, can become aggressive. Treatment is to cut out the cancerous cells but there is often a high chance of the disease recurring. Identifying normal tissue that has the potential to become cancerous prior to treatment could ensure complete removal and lower the risk of cancer reoccurring after treatment.

Despite decades of intense research, there are currently very few proficient stem cell biomarkers for the cornea. Now a team lead by Frank Martin at the University of Lancaster, UK, have used the sensitive and high-throughput approach of synchrotron-based Fourier-transform infrared microspectroscopy to create an image map of cornea samples to recognise differences between cell types and highlight prospective biomarkers.

To read Jennifer Newton’s full Highlights in Chemical Biology article, please click here: Looking cancer in the eye

Evidence for a stem-cell lineage in corneal squamous cell carcinoma using synchrotron-based Fourier-transform infrared microspectroscopy and multivariate analysis
Jemma G. Kelly, Takahiro Nakamura, Shigeru Kinoshita, Nigel J. Fullwood and Francis L. Martin, Analyst, 2010
DOI:
10.1039/c0an00507j

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