Archive for the ‘Top 10’ Category

Top 10 most accessed Toxicology Research articles from January – March 2015

From January – March 2015, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014,3, 418-432
DOI: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/C2TX20031G

An introduction to systems toxicology
Nick J. Plant
Toxicol. Res., 2015,4, 9-22
DOI: 10.1039/C4TX00058G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond

Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/C2TX20006F

DNA damage by oxo- and peroxo-chromium(v) complexes: insight into the mutation and carcinogenesis mechanisms
Lamis Judah, Roberto Marin, Diane Stroup, Chrys Wesdemiotis and Rathindra N. Bose
Toxicol. Res., 2014,3, 56-66
DOI: 10.1039/C3TX50061F

A comparative cytotoxicity study of TiO2 nanoparticles under light and dark conditions at low exposure concentrations

Swayamprava Dalai, Sunandan Pakrashi, R. S. Suresh Kumar, N. Chandrasekaran and Amitava Mukherjee
Toxicol. Res., 2012,1, 116-130
DOI: 10.1039/C2TX00012A

Interaction of tannic acid with carbon nanotubes: enhancement of dispersibility and biocompatibility

Xiaoyong Zhang, Meiying Liu, Xiqi Zhang, Fengjie Deng, Cuiying Zhou, Junfeng Hui, Wanyun Liu and Yen Wei
Toxicol. Res., 2015,4, 160-168
DOI: 10.1039/C4TX00066H

An unexpected increase of toxicity of amino acid-containing ionic liquids
Ksenia S. Egorova, Marina M. Seitkalieva, Alexandra V. Posvyatenko and Valentine P. Ananikov
Toxicol. Res., 2015,4, 152-159
DOI: 10.1039/C4TX00079J

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir
Toxicol. Res., 2014,3, 11-22
DOI: 10.1039/C3TX50075F

New structural alerts for Ames mutagenicity discovered using emerging pattern mining techniques
Laurence Coquin, Steven J. Canipa, William C. Drewe, Lilia Fisk, Valerie J. Gillet, Mukesh Patel, Jeffrey Plante, Richard J. Sherhod and Jonathan D. Vessey
Toxicol. Res., 2015,4, 46-56
DOI: 10.1039/C4TX00071D

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Top 10 most accessed Toxicology Research articles from October – December 2014

From October – December 2014, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI
: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles
Rabbab Oun, Rafael S. Floriano, Lyle Isaacs, Edward G. Rowan and Nial J. Wheate
Toxicol. Res., 2014, 3, 447-455
DOI: 10.1039/C4TX00082J

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
Xiaoyong Zhang, ShiQi Wang, Meiying Liu, Junfeng Hui, Bin Yang, Lei Tao and Yen Wei
Toxicol. Res., 2013, 2, 335-342
DOI: 10.1039/C3TX50021G

Translation of off-target effects: prediction of ADRs by integrated experimental and computational approach
Laszlo Urban, Mateusz Maciejewski, Eugen Lounkine, Steven Whitebread, Jeremy L. Jenkins, Jacques Hamon, Alexander Fekete and Patrick Y. Muller
Toxicol. Res., 2014, 3, 433-444
DOI: 10.1039/C4TX00077C

The toxicological assessment of two anti-obesity drugs in C. elegans
Layla Aitlhadj and Stephen R. Stürzenbaum
Toxicol. Res., 2013, 2, 145-150
DOI: 10.1039/C2TX20096A

A comparative cytotoxicity study of TiO2 nanoparticles under light and dark conditions at low exposure concentrations
Swayamprava Dalai, Sunandan Pakrashi, R. S. Suresh Kumar, N. Chandrasekaran and Amitava Mukherjee
Toxicol. Res., 2012, 1, 116-130
DOI: 10.1039/C2TX00012A

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant
Toxicol. Res., 2013, 2, 328-334
DOI: 10.1039/C3TX50034A

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Q2 Top Ten most accessed Toxicology Research articles

During the months April – June 2014, the most downloaded Toxicology Research articles were:

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir
Toxicol. Res., 2014, 3, 11-22
DOI: 10.1039/C3TX50075F

Cellular responses of aniline oligomers: a preliminary study
Xiaoyong Zhang, Hongxu Qi, Shiqi Wang, Lin Feng, Yan Ji, Lei Tao, Shuxi Li and Yen Wei
Toxicol. Res., 2012, 1, 201-205
DOI: 10.1039/C2TX20035J

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin
Toxicol. Res., 2013, 2, 209-234
DOI: 10.1039/C3TX20093K

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park
Toxicol. Res., 2014, 3, 75-85
DOI: 10.1039/C3TX50077B

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant
Toxicol. Res., 2013, 2, 328-334
DOI: 10.1039/C3TX50034A

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach
Toxicol. Res., 2013, 2, 235-244
DOI: 10.1039/C3TX50027F

After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver
Krzysztof Wrzesinski and Stephen J. Fey
Toxicol. Res., 2013, 2, 123-135
DOI: 10.1039/C2TX20060K

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

Interesting read? Please share your thoughts below!

And remember, you can submit direct to Toxicology Research here

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Q1 Top Ten most accessed Toxicology Research articles

During January, February and March this year, the following articles were the Top Ten most accessed:

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park  
Toxicol. Res., 2014,3, 75-85
DOI: 10.1039/c3tx50077b

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013,2, 23-39
DOI: 10.1039/c2tx20051a

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment
Steve Gutsell and Paul Russell  
Toxicol. Res., 2013,2, 299-307
DOI: 10.1039/c3tx50024a

Evaluation of copper iodide and copper phosphate nanoparticles for their potential cytotoxic effect
Dipranjan Laha, Debalina Bhattacharya, Arindam Pramanik, Chitta Ranjan Santra, Panchanan Pramanik and Parimal Karmakar  
Toxicol. Res., 2012,1, 131-136
DOI: 10.1039/c2tx00009a

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013,2, 209-234
DOI: 10.1039/c3tx20093k

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013,2, 235-244
DOI: 10.1039/c3tx50027f

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir  
Toxicol. Res., 2014,3, 11-22
DOI: 10.1039/c3tx50075f

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei  
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/c2tx20006f

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant  
Toxicol. Res., 2013,2, 328-334
DOI: 10.1039/c3tx50034a

Comparative cytotoxicity of cadmium forms (CdCl2, CdO, CdS micro- and nanoparticles) in renal cells
Béatrice L’Azou, Isabelle Passagne, Sandra Mounicou, Mona Tréguer-Delapierre, Igor Puljalté, Joanna Szpunar, Ryszard Lobinski and Céline Ohayon-Courtès  
Toxicol. Res., 2014,3, 32-41
DOI: 10.1039/c3tx50063b

If you have any comments on any of these articles we’d love to hear them, so please leave these in the comment box below!

Do you have any article which is ready to submit to Toxicology Research? Why not submit to us here today!

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