Archive for the ‘Top 10’ Category

Top 10 most downloaded articles: October – December 2016

We are delighted to share with you the top 10 most downloaded articles in Toxicology Research  from October–December 2016. These papers are free to access for the next two weeks with a free publishing personal account – register here.

We hope you enjoy reading these highly accessed articles, and we welcome your future submissions to the journal.

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014,3, 418-432
DOI: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/C2TX20031G

Characterization of a functional C3A liver spheroid model
Harriet Gaskell, Parveen Sharma, Helen E. Colley, Craig Murdoch, Dominic P. Williams and Steven D. Webb
Toxicol. Res., 2016,5, 1053-1065
DOI: 10.1039/C6TX00101

Development and use of in vitro alternatives to animal testing by the pharmaceutical industry 1980–2013
Jen-Yin Goh, Richard J. Weaver, Libby Dixon, Nicola J. Platt and Ruth A. Roberts
Toxicol. Res., 2015,4, 1297-1307
DOI: 10.1039/C5TX00123D

Proteasome inhibitors bortezomib and carfilzomib used for the treatment of multiple myeloma do not inhibit the serine protease HtrA2/Omi
Vilmos Csizmadia, Paul Hales, Christopher Tsu, Jingya Ma, Jiejin Chen, Pooja Shah, Paul Fleming, Joseph J. Senn, Vivek J. Kadambi, Larry Dick and Francis S. Wolenski
Toxicol. Res., 2016,5, 1619-1628
DOI: 10.1039/C6TX00220J

Effects of monoolein-based cubosome formulations on lipid droplets and mitochondria of HeLa cells
Angela Maria Falchi, Antonella Rosa, Angela Atzeri, Alessandra Incani, Sandrina Lampis, Valeria Meli, Claudia Caltagirone and Sergio Murgia
Toxicol. Res., 2015,4, 1025-1036
DOI: 10.1039/C5TX00078E

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/C2TX20006F

Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons
Emma Wincent, Florane Le Bihanic and Kristian Dreij
Toxicol. Res., 2016,5, 788-799
DOI: 10.1039/C6TX00004E

Improving the prediction of organism-level toxicity through integration of chemical, protein target and cytotoxicity qHTS data
Chad H. G. Allen, Alexios Koutsoukas, Isidro Cortés-Ciriano, Daniel S. Murrell, Thérèse E. Malliavin, Robert C. Glen and Andreas Bender
Toxicol. Res., 2016,5, 883-894
DOI: 10.1039/C5TX00406C

Gender specific differences in the liver proteome of rats exposed to short term and low-concentration hexabromocyclododecane (HBCD)
I. Miller, C. Diepenbroek, E. Rijntjes, J. Renaut, K. J. Teerds, C. Kwadijk, S. Cambier, A. J. Murk, A. C. Gutleb and T. Serchi
Toxicol. Res., 2016,5, 1273-1283
DOI: 10.1039/C6TX00166A

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Top 10 most downloaded articles: July – September 2016

We are delighted to share with you the top 10 most downloaded articles in Toxicology Research from July–September 2016. These papers are free to access for the next two weeks with a free publishing personal account – register here.

Toxicology Research, led by Editor-in-Chief Professor Nigel Gooderham (Imperial College, London), is a multidisciplinary journal covering high impact research in fundamental, translational and applied areas of toxicology. The Journal is published by the Royal Society of Chemistry and is the official journal of the British Toxicology Society and the Chinese Society of Toxicology. More details about the journal, the scope and our author guidelines are available on our website.

We hope you enjoy reading these highly accessed articles, and we welcome your future submissions to the Journal.

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI: 10.1039/C4TX00047A

Characterization of a functional C3A liver spheroid model
Harriet Gaskell, Parveen Sharma, Helen E. Colley, Craig Murdoch, Dominic P. Williams and Steven D.Webb
Toxicol. Res., 2016, 5, 1053-1065
DOI: 10.1039/C6TX00101G

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

Acetaminophen-induced S-nitrosylation and S-sulfenylation signalling in 3D cultured hepatocarcinoma cell spheroids
Katarzyna Wojdyla, Krzysztof Wrzesinski, James Williamson, Stephen J. Fey and Adelina Rogowska-Wrzesinska
Toxicol. Res., 2016, 5, 905-920
DOI: 10.1039/C5TX00469A

Development and use of in vitro alternatives to animal testing by the pharmaceutical industry 1980–2013
Jen-Yin Goh, Richard J. Weaver, Libby Dixon, Nicola J. Platt and Ruth A. Roberts
Toxicol. Res., 2015, 4, 1297-1307
DOI: 10.1039/C5TX00123D

Improving the prediction of organism-level toxicity through integration of chemical, protein target and cytotoxicity qHTS data
Chad H. G. Allen, Alexios Koutsoukas, Isidro Cortés-Ciriano, Daniel S. Murrell, Thérèse E. Malliavin, Robert C. Glen and Andreas Bender
Toxicol. Res., 2016, 5, 883-894
DOI: 10.1039/C5TX00406C

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

Induction and inhibition of human cytochrome P4501 by oxygenated polycyclic aromatic hydrocarbons
Emma Wincent, Florane Le Bihanic and Kristian Dreij
Toxicol. Res., 2016, 5, 788-799
DOI: 10.1039/C6TX00004E

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Effects of monoolein-based cubosome formulations on lipid droplets and mitochondria of HeLa cells
Angela Maria Falchi, Antonella Rosa, Angela Atzeri, Alessandra Incani, Sandrina Lampis, Valeria Meli, Claudia Caltagirone and Sergio Murgia
Toxicol. Res., 2015, 4, 1025-1036
DOI: 10.1039/C5TX00078E

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Most downloaded articles in Toxicology Research – see what your peers have been reading

We are delighted to share with you the top 10 most downloaded articles in Toxicology Research from 1st April 2016 – 30th June 2016. These papers are free to access for the next two weeks with a free publishing personal account – register here.

Toxicology Research, led by Editor-in-Chief Professor Nigel Gooderham (Imperial College, London), is a multidisciplinary journal covering high impact research in fundamental, translational and applied areas of toxicology. The Journal is published by the Royal Society of Chemistry and is the official journal of the British Toxicology Society and the Chinese Society of Toxicology. More details about the journal, the scope and our author guidelines are available on our website.

We hope you enjoy reading these highly accessed articles, and we welcome your future submissions to the Journal.

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014,3, 418-432
DOI: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/C2TX20031G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/C2TX20006F

Development and use of in vitro alternatives to animal testing by the pharmaceutical industry 1980–2013
Jen-Yin Goh, Richard J. Weaver, Libby Dixon, Nicola J. Platt and Ruth A. Roberts
Toxicol. Res., 2015,4, 1297-1307
DOI: 10.1039/C5TX00123D

Dibutyl phthalate induced oxidative stress does not lead to a significant adjuvant effect on a mouse asthma model
Shaohui Chen, Huihui You, Lin Mao and Xu Yang
Toxicol. Res., 2015,4, 260-269
DOI: 10.1039/C4TX00096J

Effects of monoolein-based cubosome formulations on lipid droplets and mitochondria of HeLa cells
Angela Maria Falchi, Antonella Rosa, Angela Atzeri, Alessandra Incani, Sandrina Lampis, Valeria Meli, Claudia Caltagirone and Sergio Murgia
Toxicol. Res., 2015,4, 1025-1036
DOI: 10.1039/C5TX00078E

Synergistic interaction between lipid-loading and doxorubicin exposure in Huh7 hepatoma cells results in enhanced cytotoxicity and cellular oxidative stress: implications for acute and chronic care of obese cancer patients
S. AlGhamdi, V. Leoncikas, K. E. Plant and N. J. Plant
Toxicol. Res., 2015,4, 1479-1487
DOI: 10.1039/C5TX00173K

In vitro models for neurotoxicology research
Daniel José Barbosa, João Paulo Capela, Maria de Lourdes Bastos and Félix Carvalho
Toxicol. Res., 2015,4, 801-842
DOI: 10.1039/C4TX00043A

Health hazards of methylammonium lead iodide based perovskites: cytotoxicity studies
Iness R. Benmessaoud, Anne-Laure Mahul-Mellier, Endre Horváth, Bohumil Maco, Massimo Spina, Hilal A. Lashuel and Làszló Forró
Toxicol. Res., 2016,5, 407-419
DOI: 10.1039/C5TX00303B

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013,2, 23-39
DOI: 10.1039/C2TX20051A

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Top 10 most accessed articles from October – December 2015

From October – December 2015, our most downloaded Toxicology Research articles were:

Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI: 10.1039/C4TX00047A, Review Article

Novel in vitro and mathematical models for the prediction of chemical toxicity

Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G, Review Article

Daniel José Barbosa, João Paulo Capela, Maria de Lourdes Bastos and Félix Carvalho
Toxicol. Res., 2015, 4, 801-842
DOI: 10.1039/C4TX00043A, Review Article

Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F, Paper

Isabel Costa, Félix Carvalho, Teresa Magalhães, Paula Guedes de Pinho, Ricardo Silvestre and Ricardo Jorge Dinis-Oliveira
Toxicol. Res., 2015, 4, 1443-1452
DOI: 10.1039/C5TX00209E, Paper

Abdullah Al-Ali, Neenu Singh, Bella Manshian, Tom Wilkinson, John Wills, Gareth J. S. Jenkins and Shareen H. Doak
Toxicol. Res., 2015, 4, 623-633
DOI: 10.1039/C4TX00175C, Paper

S. AlGhamdi, V. Leoncikas, K. E. Plant and N. J. Plant
Toxicol. Res., 2015, 4, 1479-1487
DOI: 10.1039/C5TX00173K, Paper

Parodi Daniela A, Sjarif Jasmine, Chen Yichang and Allard Patrick
Toxicol. Res., 2015, 4, 645-654
DOI: 10.1039/C4TX00141A, Paper

Henrik Klingberg, Lene B. Oddershede, Katrin Loeschner, Erik H. Larsen, Steffen Loft and Peter Møller
Toxicol. Res., 2015, 4, 655-666
DOI: 10.1039/C4TX00061G, Paper

Nick J. Plant
Toxicol. Res., 2015, 4, 9-22
DOI: 10.1039/C4TX00058G, Review Article
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Top 10 most accessed articles from July – September 2015

From July – September 2015, our most downloaded Toxicology Research articles were:

Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI: 10.1039/C4TX00047A, Review Article

Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G, Review Article

Abdullah Al-Ali, Neenu Singh, Bella Manshian, Tom Wilkinson, John Wills, Gareth J. S. Jenkins and Shareen H. Doak
Toxicol. Res., 2015, 4, 623-633
DOI: 10.1039/C4TX00175C, Paper

Parodi Daniela A, Sjarif Jasmine, Chen Yichang and Allard Patrick
Toxicol. Res., 2015, 4, 645-654
DOI: 10.1039/C4TX00141A, Paper

Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F, Paper

Viktoria Vágány and Andrew G. Smith
Toxicol. Res., 2015, 4, 1128-1142
DOI: 10.1039/C5TX00011D, Review Article

Daniel José Barbosa, João Paulo Capela, Maria de Lourdes Bastos and Félix Carvalho
Toxicol. Res., 2015, 4, 801-842
DOI: 10.1039/C4TX00043A, Review Article

Chibuzor Uchea, Stewart F. Owen and J. Kevin Chipman
Toxicol. Res., 2015, 4, 494-507
DOI: 10.1039/C4TX00160E, Paper

Nick J. Plant
Toxicol. Res., 2015, 4, 9-22
DOI: 10.1039/C4TX00058G, Review Article

Vipul Agarwal, Edwin S. Tjandra, K. Swaminathan Iyer, Barry Humfrey, Mark Fear, Fiona M. Wood, Sarah Dunlop and Colin L. Raston
Toxicol. Res., 2014, 3, 223-227
DOI: 10.1039/C4TX00004H, Communication

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Top 10 most accessed Toxicology Research articles from April – June 2015

From April – June 2015, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity

Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

Quantum dot induced cellular perturbations involving varying toxicity pathways
Abdullah Al-Ali, Neenu Singh, Bella Manshian, Tom Wilkinson, John Wills, Gareth J. S. Jenkins and Shareen H. Doak
Toxicol. Res., 2015, 4, 623-633
DOI: 10.1039/C4TX00175C

An introduction to systems toxicology
Nick J. Plant
Toxicol. Res., 2015, 4, 9-22
DOI: 10.1039/C4TX00058G

Reproductive toxicity and meiotic dysfunction following exposure to the pesticides Maneb, Diazinon and Fenarimol
Parodi Daniela A, Sjarif Jasmine, Chen Yichang and Allard Patrick
Toxicol. Res., 2015, 4, 645-654
DOI: 10.1039/C4TX00141A

Contributors to the New Talents issue

Toxicol. Res., 2015, 4, 541-544
DOI: 10.1039/C5TX90009C
From themed collection New Talents

Uptake of gold nanoparticles in primary human endothelial cells
Henrik Klingberg, Lene B. Oddershede, Katrin Loeschner, Erik H. Larsen, Steffen Loft and Peter Møller
Toxicol. Res., 2015, 4, 655-666
DOI: 10.1039/C4TX00061G

Manganese-induced neurotoxicity: from C. elegans to humans

Pan Chen, Sudipta Chakraborty, Tanara V. Peres, Aaron B. Bowman and Michael Aschner
Toxicol. Res., 2015, 4, 191-202
DOI: 10.1039/C4TX00127C

Interaction of tannic acid with carbon nanotubes: enhancement of dispersibility and biocompatibility
Xiaoyong Zhang, Meiying Liu, Xiqi Zhang, Fengjie Deng, Cuiying Zhou, Junfeng Hui, Wanyun Liu and Yen Wei
Toxicol. Res., 2015, 4, 160-168
DOI: 10.1039/C4TX00066H

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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HOT articles in Toxicology Research

Take a look at our recent HOT Toxicology Research articles, these are now free to access for the next few weeks!

CpG site-specific RASSF1a hypermethylation is associated with occupational PAH exposure and genomic instability
Zhini He, Huawei Duan, Biao Zhang, Miao Li, Liping Chen, Bo Zhang, Xiaonian Zhu, Chen Gao, Jie Li, Xiao Zhang, Jingmaio Zhang, Shan Wang, Xiaowen Zeng, Daochuan Li, Xiumei Xing, Zhengbao Zhang, Lu Ma, Qing Bai, Caixia Liu, Yongmei Xiao, Yuxin Zheng and Wen Chen
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C5TX00013K

Graphical Abstract


Molecular modeling and spectroscopic study of quinone–protein adducts: insight into toxicity, selectivity, and reversibility
Mohamed Saleh Elgawish, Naoya Kishikawa, Mohamed A. Helal, Kaname Ohyama and Naotaka Kuroda
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C5TX00098J

Graphical Abstract


p, p’- Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways
Li Song, meirong zhao, Jianxin Liu, Zhuoyu Li, Hong Xiao and Weiping Liu
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00006H

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Top 10 most accessed Toxicology Research articles from January – March 2015

From January – March 2015, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014,3, 418-432
DOI: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/C2TX20031G

An introduction to systems toxicology
Nick J. Plant
Toxicol. Res., 2015,4, 9-22
DOI: 10.1039/C4TX00058G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond

Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/C2TX20006F

DNA damage by oxo- and peroxo-chromium(v) complexes: insight into the mutation and carcinogenesis mechanisms
Lamis Judah, Roberto Marin, Diane Stroup, Chrys Wesdemiotis and Rathindra N. Bose
Toxicol. Res., 2014,3, 56-66
DOI: 10.1039/C3TX50061F

A comparative cytotoxicity study of TiO2 nanoparticles under light and dark conditions at low exposure concentrations

Swayamprava Dalai, Sunandan Pakrashi, R. S. Suresh Kumar, N. Chandrasekaran and Amitava Mukherjee
Toxicol. Res., 2012,1, 116-130
DOI: 10.1039/C2TX00012A

Interaction of tannic acid with carbon nanotubes: enhancement of dispersibility and biocompatibility

Xiaoyong Zhang, Meiying Liu, Xiqi Zhang, Fengjie Deng, Cuiying Zhou, Junfeng Hui, Wanyun Liu and Yen Wei
Toxicol. Res., 2015,4, 160-168
DOI: 10.1039/C4TX00066H

An unexpected increase of toxicity of amino acid-containing ionic liquids
Ksenia S. Egorova, Marina M. Seitkalieva, Alexandra V. Posvyatenko and Valentine P. Ananikov
Toxicol. Res., 2015,4, 152-159
DOI: 10.1039/C4TX00079J

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir
Toxicol. Res., 2014,3, 11-22
DOI: 10.1039/C3TX50075F

New structural alerts for Ames mutagenicity discovered using emerging pattern mining techniques
Laurence Coquin, Steven J. Canipa, William C. Drewe, Lilia Fisk, Valerie J. Gillet, Mukesh Patel, Jeffrey Plante, Richard J. Sherhod and Jonathan D. Vessey
Toxicol. Res., 2015,4, 46-56
DOI: 10.1039/C4TX00071D

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Top 10 most accessed Toxicology Research articles from October – December 2014

From October – December 2014, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI
: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles
Rabbab Oun, Rafael S. Floriano, Lyle Isaacs, Edward G. Rowan and Nial J. Wheate
Toxicol. Res., 2014, 3, 447-455
DOI: 10.1039/C4TX00082J

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
Xiaoyong Zhang, ShiQi Wang, Meiying Liu, Junfeng Hui, Bin Yang, Lei Tao and Yen Wei
Toxicol. Res., 2013, 2, 335-342
DOI: 10.1039/C3TX50021G

Translation of off-target effects: prediction of ADRs by integrated experimental and computational approach
Laszlo Urban, Mateusz Maciejewski, Eugen Lounkine, Steven Whitebread, Jeremy L. Jenkins, Jacques Hamon, Alexander Fekete and Patrick Y. Muller
Toxicol. Res., 2014, 3, 433-444
DOI: 10.1039/C4TX00077C

The toxicological assessment of two anti-obesity drugs in C. elegans
Layla Aitlhadj and Stephen R. Stürzenbaum
Toxicol. Res., 2013, 2, 145-150
DOI: 10.1039/C2TX20096A

A comparative cytotoxicity study of TiO2 nanoparticles under light and dark conditions at low exposure concentrations
Swayamprava Dalai, Sunandan Pakrashi, R. S. Suresh Kumar, N. Chandrasekaran and Amitava Mukherjee
Toxicol. Res., 2012, 1, 116-130
DOI: 10.1039/C2TX00012A

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant
Toxicol. Res., 2013, 2, 328-334
DOI: 10.1039/C3TX50034A

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Q2 Top Ten most accessed Toxicology Research articles

During the months April – June 2014, the most downloaded Toxicology Research articles were:

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir
Toxicol. Res., 2014, 3, 11-22
DOI: 10.1039/C3TX50075F

Cellular responses of aniline oligomers: a preliminary study
Xiaoyong Zhang, Hongxu Qi, Shiqi Wang, Lin Feng, Yan Ji, Lei Tao, Shuxi Li and Yen Wei
Toxicol. Res., 2012, 1, 201-205
DOI: 10.1039/C2TX20035J

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin
Toxicol. Res., 2013, 2, 209-234
DOI: 10.1039/C3TX20093K

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park
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