Archive for the ‘News’ Category

Issue 5 now online!

Graphical AbstractThe front cover of issue 5 features artwork by  Shao-Chen Sun from Nanjing Agricultural University. With his colleagues, Shao-Chen explored possible mechanisms for the toxic effects of ZEN on pig oocytes. They cultured porcine oocytes to maturation in media with different ZEN concentrations (5–30 μM), after which they analyzed oocyte oxidative stress status, autophagy, early apoptosis, and epigenetic modifications by immunofluorescence, quantitative real-time PCR analysis and western blot approaches.

Want to know more? Read the full article below – its free to access for the next 6 weeks!

Jun Han, Ting Wang, Le Fu, Liang-Yu Shi, Cheng-Cheng Zhu, Jun Liu, Yu Zhang, Xiang-Shun Cui, Nam-Hyung Kim and Shao-Chen Sun
Toxicol. Res., 2015, 4, 1184-1194
DOI: 10.1039/C5TX00070J

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Top 10 most accessed Toxicology Research articles from April – June 2015

From April – June 2015, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity

Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

Quantum dot induced cellular perturbations involving varying toxicity pathways
Abdullah Al-Ali, Neenu Singh, Bella Manshian, Tom Wilkinson, John Wills, Gareth J. S. Jenkins and Shareen H. Doak
Toxicol. Res., 2015, 4, 623-633
DOI: 10.1039/C4TX00175C

An introduction to systems toxicology
Nick J. Plant
Toxicol. Res., 2015, 4, 9-22
DOI: 10.1039/C4TX00058G

Reproductive toxicity and meiotic dysfunction following exposure to the pesticides Maneb, Diazinon and Fenarimol
Parodi Daniela A, Sjarif Jasmine, Chen Yichang and Allard Patrick
Toxicol. Res., 2015, 4, 645-654
DOI: 10.1039/C4TX00141A

Contributors to the New Talents issue

Toxicol. Res., 2015, 4, 541-544
DOI: 10.1039/C5TX90009C
From themed collection New Talents

Uptake of gold nanoparticles in primary human endothelial cells
Henrik Klingberg, Lene B. Oddershede, Katrin Loeschner, Erik H. Larsen, Steffen Loft and Peter Møller
Toxicol. Res., 2015, 4, 655-666
DOI: 10.1039/C4TX00061G

Manganese-induced neurotoxicity: from C. elegans to humans

Pan Chen, Sudipta Chakraborty, Tanara V. Peres, Aaron B. Bowman and Michael Aschner
Toxicol. Res., 2015, 4, 191-202
DOI: 10.1039/C4TX00127C

Interaction of tannic acid with carbon nanotubes: enhancement of dispersibility and biocompatibility
Xiaoyong Zhang, Meiying Liu, Xiqi Zhang, Fengjie Deng, Cuiying Zhou, Junfeng Hui, Wanyun Liu and Yen Wei
Toxicol. Res., 2015, 4, 160-168
DOI: 10.1039/C4TX00066H

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Issue 4 now online!

Graphical Abstract

The front cover of issue 4 features artwork by Arthur Grollman (Stony Brook University, USA)  and Robert Turesky (University of Minnesota, USA). With their colleagues, Grollman and Turesky highlight novel approaches to quantify exposure to AA, by analysis of aristolactam (AL) DNA adducts, employing ultraperformance liquid chromatography–electrospray ionization/multistage mass spectrometry (UPLC-ESI/MSn).

Intesrested to know more? Read the full article below – its free to access for the next 6 weeks:

New approaches for biomonitoring exposure to the human carcinogen aristolochic acid
Byeong Hwa Yun, Viktoriya S. Sidorenko, Thomas A. Rosenquist, Kathleen G. Dickman, Arthur P. Grollman and Robert J. Turesky
Toxicol. Res., 2015, 4, 763-776
DOI: 10.1039/C5TX00052A


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Toxicology Research 2014 Impact Factor

Toxicology Research 2014 Impact Factor is 3.98We are pleased to announce that the latest Impact Factor* for Toxicology Research is 3.98, according to the 2014 Journal Citation Reports ® (JCR). This is the first full Impact Factor for the Journal, placing us in the Top Ten of the JCR “toxicology” subject category.

We would like to thank all of our authors, referees, Editorial Board and Advisory Board for their contributions to the success of the Journal.

Click here to find out how other Royal Society of Chemistry journals performed in the latest Impact Factor release.

*The Impact Factor provides an indication of the average number of citations per paper. Produced annually, Impact Factors are calculated by dividing the number of citations in a year by the number of citeable articles published in the preceding two years.

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HOT articles in Toxicology Research

Take a look at our recent HOT Toxicology Research articles, these are now free to access for the next few weeks!

CpG site-specific RASSF1a hypermethylation is associated with occupational PAH exposure and genomic instability
Zhini He, Huawei Duan, Biao Zhang, Miao Li, Liping Chen, Bo Zhang, Xiaonian Zhu, Chen Gao, Jie Li, Xiao Zhang, Jingmaio Zhang, Shan Wang, Xiaowen Zeng, Daochuan Li, Xiumei Xing, Zhengbao Zhang, Lu Ma, Qing Bai, Caixia Liu, Yongmei Xiao, Yuxin Zheng and Wen Chen
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C5TX00013K

Graphical Abstract


Molecular modeling and spectroscopic study of quinone–protein adducts: insight into toxicity, selectivity, and reversibility
Mohamed Saleh Elgawish, Naoya Kishikawa, Mohamed A. Helal, Kaname Ohyama and Naotaka Kuroda
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C5TX00098J

Graphical Abstract


p, p’- Dichlorodiphenyltrichloroethane inhibits the apoptosis of colorectal adenocarcinoma DLD1 cells through PI3K/AKT and Hedgehog/Gli1 signaling pathways
Li Song, meirong zhao, Jianxin Liu, Zhuoyu Li, Hong Xiao and Weiping Liu
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00006H

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Poster prize winner at the 2nd Eco-toxicology conference 2015

Toxicology Research were delighted to sponsor a poster prize at the 2nd Eco-toxicology conference, which took place from the 25th – 28th April 2015 in Xiamen, China. Many congratulations to Liang-ying He (Guangzhou Institute of Geochemistry, Chinese Academy of Sciences) for winning this prize with their poster entitiled: “Dissemination of Antibiotic Resistance Genes in Representative Broiler Feedlots Environments: Identification of Indicator ARGs and Correlations with Environmental Variables“.

“Broiler feedlots may represent an important source of antibiotic resistance genes (ARGs) in the environment. However, the prevalence and dissemination mechanisms of various types of ARGs in the environment of broiler feedlots have not previously been identified. We examined the occurrence, abundance and variation of ARGs conferring resistance to chloramphenicols, sulfonamides and tetracyclines in the environments of two representative types of broiler feedlots (free range and indoor) and assessed their dissemination mechanisms. Horizontal gene transfer and co-selection were found to play important roles in ARG dissemination in the environment. fexA, sul1 and tetW could be reliable indicator genes to surrogate anthropogenic sources of ARGs in boiler feedlots. The distribution and transportation of ARGs from the boiler feedlots to the receiving environments were correlated with environmental variables. The findings highlight the contribution of some chemicals such as antibiotics and metals to the development of ARGs in broiler feedlots environments; and the observed ARG dissemination mechanism in the broiler feedlots facilitates the development of effective mitigation measures.”

Many congratulations to Liang-ying on receiving your prize

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Issue 3 now online!

Graphical Abstract

The front cover of issue 3 features artwork by Shareen H. Doak from Swansea University. With her colleagues Shareen asseses the impact of varying QD surface chemistry on cellular uptake and a range of indicators for cell perturbation following exposure.

Interested to know more? Read the full article below – its free to access for the next 6 weeks:

Quantum dot induced cellular perturbations involving varying toxicity pathways
Abdullah Al-Ali, Neenu Singh, Bella Manshian, Tom Wilkinson, John Wills, Gareth J. S. Jenkins and Shareen H. Doak
Toxicol. Res., 2015, 4, 623-633
DOI: 10.1039/C4TX00175C


This issue is a part-themed issue on the topic of New Talents. Click here to read the editorial by Professor Nigel Gooderham.

Keep up-to-date with the latest content in Toxicology Research by registering for our free table of contents alerts.

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HOT articles in Toxicology Research

Take a look at our recent HOT Toxicology Research articles, these are now free to access for the next few weeks!

Graphical Abstract

Lack of effect of metofluthrin and sodium phenobarbital on replicative DNA synthesis and Ki-67 mRNA expression in cultured human hepatocytes
Tomoya Yamada, Hiroko Kikumoto, Brian G. Lake and Satoshi Kawamura
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00217B

An Introduction to Systems Toxicology
Nick J. Plant
Toxicol. Res., 2015, 4, 9-22
DOI: 10.1039/C4TX00058G

Reproducibility in Experimentation – the implications for regulatory toxicology.
Sir Colin Berry
Toxicol. Res., 2014, 3, 411-417
DOI: 10.1039/C4TX00069B

Graphical Abstract

Reproductive toxicity and meiotic dysfunction following exposure to the pesticides Maneb, Diazinon and Fenarimol.
Parodi Daniela A, Sjarif Jasmine, Chen Yichang and Allard Patrick
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00141A

Cerium dioxide nanoparticles protect against oxidative stress induced injury through modulation of TGF-ß signalling
Chang Guo, Rachel Smith, Timothy W. Gant and Martin O. Leonard
Toxicol. Res., 2015,4, 464-475
DOI: 10.1039/C4TX00210E

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Top 10 most accessed Toxicology Research articles from October – December 2014

From October – December 2014, our most downloaded Toxicology Research articles were:

Statistical evaluation of toxicological bioassays – a review
Ludwig A. Hothorn
Toxicol. Res., 2014, 3, 418-432
DOI
: 10.1039/C4TX00047A

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

The ex vivo neurotoxic, myotoxic and cardiotoxic activity of cucurbituril-based macrocyclic drug delivery vehicles
Rabbab Oun, Rafael S. Floriano, Lyle Isaacs, Edward G. Rowan and Nial J. Wheate
Toxicol. Res., 2014, 3, 447-455
DOI: 10.1039/C4TX00082J

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
Xiaoyong Zhang, ShiQi Wang, Meiying Liu, Junfeng Hui, Bin Yang, Lei Tao and Yen Wei
Toxicol. Res., 2013, 2, 335-342
DOI: 10.1039/C3TX50021G

Translation of off-target effects: prediction of ADRs by integrated experimental and computational approach
Laszlo Urban, Mateusz Maciejewski, Eugen Lounkine, Steven Whitebread, Jeremy L. Jenkins, Jacques Hamon, Alexander Fekete and Patrick Y. Muller
Toxicol. Res., 2014, 3, 433-444
DOI: 10.1039/C4TX00077C

The toxicological assessment of two anti-obesity drugs in C. elegans
Layla Aitlhadj and Stephen R. Stürzenbaum
Toxicol. Res., 2013, 2, 145-150
DOI: 10.1039/C2TX20096A

A comparative cytotoxicity study of TiO2 nanoparticles under light and dark conditions at low exposure concentrations
Swayamprava Dalai, Sunandan Pakrashi, R. S. Suresh Kumar, N. Chandrasekaran and Amitava Mukherjee
Toxicol. Res., 2012, 1, 116-130
DOI: 10.1039/C2TX00012A

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant
Toxicol. Res., 2013, 2, 328-334
DOI: 10.1039/C3TX50034A

Interesting read? Let us know your thoughts below.

And remember, you can submit direct to Toxicology Research here

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Issue 2 now online!

Graphical Abstract

The front cover of issue 2 feautures artwork by P. Sreenivasula Reddy from Sri Venkateswara University. With his colleagues, P. Sreenivasula Reddy evaluates reproductive toxic effects of benzo(a)pyrene (BaP) in adult male Wistar rats.

Interested to know more? Read the full article below – its free to access for the next 6 weeks:

Reproductive and paternal mediated developmental toxicity of benzo(a)pyrene in adult male Wistar rats
K. Pratap Reddy, B. P. Girish and P. Sreenivasula Reddy
Toxicol. Res., 2015, 4, 223-232
DOI: 10.1039/C4TX00121D


Keep up-to-date with the latest content in Toxicology Research by registering for our free table of contents alerts.

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