Author Archive

Meet the team at EUROTOX 2013

I will be attending the 49th EUROTOX Congress in Interlaken, Switzerland, later this month. Let me know if you are attending and would like to arrange a meeting with me.

Simply email the Toxicology Research Editorial Office – I would be delighted to meet you!

 

If you haven’t already, check out the Top 10 Toxicology Research  most-accessed articles in April–June 2013, which include:

Functional assessments in repeat-dose toxicity studies: the art of the possible 
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013, 2, 209-234  

In vitro models for liver toxicity testing  
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn    
Toxicol. Res., 2013, 2, 23-39  

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds  
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013, 2, 235-244   

Novel in vitro and mathematical models for the prediction of chemical toxicity 
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton  
Toxicol. Res., 2013, 2, 40-59   

Do you want to get involved in Toxicology Research?
  • Submit your latest research
  • Sign up for the contents alerts and newsletter – keep up to date with the latest research published in the journal
  • All articles published in 2012 and 2013 are free to access. Arrange for your free access by simply filling in this short online registration form

I look forward to meeting you this September!

Marie Cote, Deputy Editor Toxicology Research

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Congratulations to Stephen Fey et al. whose Toxicology Research article is featuring in Medical News Today

The latest article by Stephen J. Fey  et al. in Toxicology Research is gathering media attention… Illustrated with another eye-catching cover, the work by this collaboration from Denmark and Switzerland looks at the HepG2/C3A cells stability following their recovery after trypsinization.  

The work has been press-released by the University of Southern Denmark: New cutting-edge cell research will lead to safer medical experiments on humans

and picked up by Medical News Today.

Read both articles by Stephen Fey et al. on the topic:

HepG2/C3A 3D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsinisation
Krzysztof Wrzesinski, Maria Chiara Magnone, Line Visby Hansen, Marianne Ehrhorn Kruse, Tobias Bergauer, Maria Bobadilla, Marcel Gubler, Jacques Mizrahi, Kelan Zhang, Christina M. Andreasen, Kira Eyð Joensen, Signe Marie Andersen, Jacob Bastholm Olesen, Ove B. Schaffalitzky de Muckadell and Stephen J. Fey
Toxicol. Res., 2013, Advance Article
DOI: 10.1039/C3TX20086H, Paper

After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver
Krzysztof Wrzesinski and Stephen J. Fey
Toxicol. Res., 2013, 2, 123-135
DOI: 10.1039/C2TX20060K

Remember, all Toxicology Research articles are Free to access until the end of 2013!

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Cells trypsinisation and toxicological responses on the cover of Toxicology Research Issue 2

Welcome to Toxicology Research Issue 2, 2013

On the cover is the work of Stephen J. Fey et al., who look at how immortal human hepatocytes cell lines re-establish levels of key physiological functions following trypsinisation.

After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver
Krzysztof Wrzesinski and Stephen J. Fey
Toxicol. Res., 2013, 2, 123-135
DOI: 10.1039/C2TX20060K

And why not read the sequel as well, now available:

HepG2/C3A 3D spheroids exhibit stable physiological functionality for at least 24 days after recovering from trypsinisation
Toxicol. Res., 2013, Advance Article
DOI: 10.1039/C3TX20086H, Paper

View the rest of the Issue now! Including a review on lead and manganese neurotoxicity.

As with all articles published in Toxicology Research, the whole of issue 2 is Free to Access upon a simple registration process.

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Toxicology Research Review Articles: A Collection

In addition to high quality research papers Toxicology Research features topical review articles across the full range of the journal scope. Since the journal launch and Issue 1  published in July last year, we have aimed at providing readers with strong reviews designed to give an interesting insight into the topic, focussing on the key developments, trends and future directions.

For the benefit of readers we bring together the reviews published so far.
 
We hope you find them interesting and stimulating to read:

Epigenetics – relevance to drug safety science
Catherine C. Priestley, Mark Anderton, Ann T. Doherty, Paul Duffy, Howard R. Mellor, Helen Powell and Ruth Roberts
Toxicol. Res., 2012, 1, 23-31

Mechanisms and modifiers of methylmercury-induced neurotoxicity
Stephanie J. B. Fretham, Samuel Caito, Ebany J. Martinez-Finley and Michael Aschner
Toxicol. Res., 2012, 1, 32-38

Mitochondrial glutathione in toxicology and disease of the kidneys
Lawrence H. Lash
Toxicol. Res., 2012, 1, 39-46

Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations
Joao B. T. Rocha, Rogerio A. Saraiva, Solange C. Garcia, Fernanda S. Gravina and Cristina W. Nogueira
Toxicol. Res., 2012, 1, 85-102

Perfluorooctane sulfonate (PFOS) and calcium channel downstream signaling molecules
Yu Wang and Yihe Jin
Toxicol. Res., 2012, 1, 103-107

Role of innate and adaptive immunity during drug-induced liver injury
C. David Williams and Hartmut Jaeschke
Toxicol. Res., 2012, 1, 161-170
 

 S-Methyl-L-cysteine sulphoxide: the Cinderella phytochemical?                                                  William M. B. Edmands, Nigel J. Gooderham, Elaine Holmes and Stephen C. Mitchell
Toxicol. Res., 2013, 2, 11-22

In vitro models for liver toxicity testing                                                                                                                                 Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59

Fancy writing a review article?  Have a topic in mind that will benefit the community? Send us your suggestions! 
  

Do you want to get involved in Toxicology Research?

  •  Submit your latest research
  •  Sign up for the contents alerts and newsletter – keep up to date with the latest research published in  the journal
  •  All articles published in 2012 and 2013 are free to access. Arrange for your free access by simply  filling in this short online registration form

 

 

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Meet the Toxicology Research Editorial team – see where and when you can meet us in 2013

The Toxicology Research Editorial team will be attending a number of conferences in 2013 and we would be delighted to meet you there.  

We’re also the team behind Toxicology Research’s sister journals Organic & Biomolecular Chemistry, MedChemComm, and Natural Product Reports, so we’ll happily discuss your interdisciplinary research work. In fact, many of our authors choose to publish their research across all of these titles.    

Here are just some of the conferences where you can meet us in the coming months:  

RSC India Roadshow, visiting Kolkata, Pune and Bangalore – 5-11 February 2013, India – View the full details, including the confirmed speakers’ list– Meet Richard
Society of Toxicology’s 52nd Annual Meeting –10-14 March 2013, San Antonio, Texas, USA – Meet Marie
40th Lakeland Heterocyclic meeting – 9-13 May 2013, Grasmere, UK – Meet Marie
Frontiers in Medicinal Chemistry (EFMC) - 23-26 June 2013, San Francisco, USA – Meet Richard
8-ISMSC (International Symposium on Macrocyclic and Supramolecular Chemistry) – 07-11 July 2013, Washington DC, USA – Meet Richard
ESOC 2013 (8th European Symposium on Organic Chemistry) – 08-12 July 2013, Marseille, France – Meet Marie
OMCOS 17 (IUPAC Conference on Organometallic Chemistry Towards Organic Synthesis)- 28 July to 01 August 2013, Fort Collins, USA – Meet Marie
EUROTOX 2013- 01-04 September 2013, Interlaken, Switzerland – Meet Marie
Fall ACS meeting- 08-12 September 2013, Indianapolis, USA – Meet Richard
Asian Medicinal Chemistry Conference – October 2013, Taipei, Taiwan – Meet Richard
15th BMOS - Brazilian Meeting on Organic Synthesis, 10-13 November 2013, Campos do Jordão, Brazil – Meet Richard    

Let us know if you are planning on attending any of these meetings, as it would be lovely to see you there!   

     

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RSC US Roadshow 2012 – Week 4: North East

Toxicology Research Editor Richard Kelly will be visiting several North East universities next week as part of the RSC US Roadshows 2012.

Week 4 sees the Royal Society of Chemistry visiting four universities in Pennsylvania and New York:

May 7th – University of Pittsburgh
May 8th – Pennsylvania State University
May 10th – University of Pennsylvania
May 11th – Columbia University

Read more about the US roadshows 2012:

Starting in mid April 2012, RSC Publishing has been touring the United States of America to share more than 170 years experience of publishing in the chemical sciences. Sixteen universities across the country are hosting these one-day events, which are open to all members of the hosting institute.

Attendees have the opportunity to explore RSC’s apps on mobile devices and meet informally with RSC editors. Lunchtime discussion groups explore reading habits and opportunities in the 21st century and an afternoon seminar give an insight into the world of scholarly publishing, with tips on how to get published in high impact journals. A demonstration of ChemSpider, and a guest lecture from an RSC associate editor or board member are available at many of the roadshows.

Follow the RSC Roadshows on Twitter – just look for #RSC2012.

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Meet the Toxicology Research team

The Toxicology Research team will be attending a number of conferences in 2012 and we would be delighted to meet you.

Dr Marie Cote, Deputy Editor

Dr Richard Kelly, Managing Editor


Here are just some of the conferences where you can meet us in the coming months:

Please let us know if you are planning on attending any of these meetings, as it would be lovely to meet you there!

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Toxicology Research in our sister journals

Our sister journals ChemComm and ChemSocRev have recently published some exciting work covering areas of the toxicological sciences…

Morteza Mahmoudi et al. discuss the biophysicochemical properties of various nanomaterials, with emphasis on currently available toxicology data and methodologies for evaluating nanoparticle toxicity:

Toxicity of nanomaterials
Shahriar Sharifi, Shahed Behzadi, Chem. Soc. Rev., 2012, Advance Article
DOI: 10.1039/C1CS15188F


Albena Ivanisevic and David Richards’ tutorial review focuses on the various coatings of inorganic materials and how their properties affect cytotoxicity:

Inorganic material coatings and their effect on cytotoxicity
Chem. Soc. Rev., 2012, Advance Article
DOI: 10.1039/C1CS15252A

And this ChemComm article by Seergazhi G. Srivatsan et al. looks at the depurination activity of toxic ribosome inactivating proteins by using an abasic site sensing fluorescent ligand:

Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins
Chem. Commun., 2012, 48, 501-503
DOI: 10.1039/C1CC16667K

 


Are you in academia or industry and conducting research in the field of toxicology?
Why not take a look at Toxicology Research,  the newest journal published by the Royal Society of Chemistry, now open for submissions


Don’t delay – be part of the first issues of Toxicology Research and submit your article online at www.rsc.org/toxicology

Sign up for Toxicology Research E-Alerts and follow us on Twitter (@ToxRes) to keep up to date with the latest news

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