The front cover of issue 1 features artwork by Yanjun Zhang from Tianjin University of Traditional Chinese Medicine. With his colleagues, Yanjun identifies more sensitive indexes for evaluating nephrotoxicity. By using gentamicin (100 mg kg−1), etimicin (100 mg kg−1) and amphotericin B (4 mg kg−1) to establish renal injury models in rats, they collected information using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry in the screening stage.
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Screening and validation for plasma biomarkers of nephrotoxicity based on metabolomics in male rats
Yubo Li, Haoyue Deng, Liang Ju, Xiuxiu Zhang, Zhenzhu Zhang, Zhen Yang, Lei Wang, Zhiguo Hou and Yanjun Zhang
Toxicol. Res., 2016, 5, 259-267
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