Issue 3 of Toxicology Research is here and ready for you to get your hands on.
On the front cover is a Paper from Gopal Chakrabarti and co-workers presenting the investigation into the target oriented molecular mechanism of the toxicity of acenaphthenequinone, a polyaromatic hydrocarbon present in diesel exhausts. Chakrabarti et al.demonstrate that acenaphthenequinone targets the microtubule cytoskeleton, and simultaneously activates mitochondria dependent cell death.
Acenaphthenequinone induces cell cycle arrest and mitochondrial apoptosis via disruption of cellular microtubules
Amlan Das, Diptiman Choudhury, Subhendu Chakrabarty, Abhijit Bhattacharya and Gopal Chakrabarti
Also featuring in this issue:
A review by C. David Williams and Hartmut Jaeschke on the role of innate and adaptive immunity during drug-induced liver injury
A paper from Ted Lock et al. using toxicogenomics to try and develop an in vitro system in renal cells to detect the carcinogenic potential of chemicals to the kidneys.
Detection of genotoxic and non-genotoxic renal carcinogens in vitro in NRK-52E cells using a transcriptomics approach
Edward A. Lock et al.
For all this and more, read the issue now for free…
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