EUROTOX 2014 conference

Professors Heather Wallace and Arstidis Tsatsakis at the Closing Ceremony of EUROTOX 2014

Professors Heather Wallace and Aristidis Tsatsakis at the Closing Ceremony of EUROTOX 2014

The 50th Congress of the European Societies of Toxicology (EUROTOX 2014) was held in Edinburgh this September. The Conference was presided by Professor Heather Wallace (Toxicology Research Editorial Board member) had an exciting programme with keynote lectures from Professor Roland Wolf and Professor Allister Vale, plenary lectures, symposia and workshops. In addition, there were state-of-the-art interactive poster sessions on large screens which were very popular with the delegates.

Katharina Dach (right) is presented with a Toxicology Research Poster Prize at Eurotox, Presented by Professor Nigel Gooderham (left) and Professor Aristidis Tsatsakis (centre)

Katharina Dach (right) wins the Toxicology Research Poster Prize at Eurotox and is presented with the prize by Toxicology Research Editor-in-Chief Professor Nigel Gooderham (left) and Professor Aristidis Tsatsakis (centre)

Toxicology Research was delighted to sponsor a poster prize at the event which was awarded to Katharina Dach (pictured right) from IUF Leibniz Institute for Environmental Medicine, Dusseldorf, Germany for her poster entitled ”Of mice and men: Mechanistic studies on the developmental neurotoxicity of polybrominated diphenyl ethers (PDBEs) in a 3D in vitro model”. Many congratulations to Katharina on receiving this prize.

Preparations for the 2015 event in Porto, Portugal, are already well underway. More details can be found on the website: http://eurotox2015.com/

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Recent HOT Toxicology Research articles

The following are HOT articles, as recommened by the reviewers of the articles. These have all been made free to access until 24th October:

Evaluation of changes in monoamine levels and apoptosis induced by cyfluthrin in rats
Dilek Guvenc, Abdurrahman Aksoy, Ayhan Gacar, Enes Atmaca, Kursad Y. Das and Tolga Guvenc
Toxicol. Res., DOI: 10.1039/C4TX00041B, Paper


MicroRNA-34c-3p is an early predictive biomarker for doxorubicin-induced glomerular injury progression in male Sprague-Dawley rats
Rachel J. Church, J. Eric McDuffie, Manisha Sonee, Monicah Otieno, Jing Ying Ma, Xuejun Liu, Paul B. Watkins and Alison H. Harrill
Toxicol. Res., 2014, 3, 384-394
DOI: 10.1039/C4TX00051J, Paper


Elevation of the intracellular Zn2+ level by 2-n-octyl-4-isothiazolin-3-one in rat thymocytes: an involvement of a temperature-sensitive Zn2+ pathway
Eri Fukunaga, Tomohiro M. Oyama and Yasuo Oyama
Toxicol. Res., 2014, Advance Article
DOI: 10.1039/C4TX00060A, Paper


An introduction to systems toxicology
Nick J. Plant
Toxicol. Res., 2014, Advance Article
DOI: 10.1039/C4TX00058G, Review Article

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Q2 Top Ten most accessed Toxicology Research articles

During the months April – June 2014, the most downloaded Toxicology Research articles were:

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012, 1, 62-68
DOI: 10.1039/C2TX20006F

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013, 2, 23-39
DOI: 10.1039/C2TX20051A

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir
Toxicol. Res., 2014, 3, 11-22
DOI: 10.1039/C3TX50075F

Cellular responses of aniline oligomers: a preliminary study
Xiaoyong Zhang, Hongxu Qi, Shiqi Wang, Lin Feng, Yan Ji, Lei Tao, Shuxi Li and Yen Wei
Toxicol. Res., 2012, 1, 201-205
DOI: 10.1039/C2TX20035J

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin
Toxicol. Res., 2013, 2, 209-234
DOI: 10.1039/C3TX20093K

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park
Toxicol. Res., 2014, 3, 75-85
DOI: 10.1039/C3TX50077B

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant
Toxicol. Res., 2013, 2, 328-334
DOI: 10.1039/C3TX50034A

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach
Toxicol. Res., 2013, 2, 235-244
DOI: 10.1039/C3TX50027F

After trypsinisation, 3D spheroids of C3A hepatocytes need 18 days to re-establish similar levels of key physiological functions to those seen in the liver
Krzysztof Wrzesinski and Stephen J. Fey
Toxicol. Res., 2013, 2, 123-135
DOI: 10.1039/C2TX20060K

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013, 2, 40-59
DOI: 10.1039/C2TX20031G

Interesting read? Please share your thoughts below!

And remember, you can submit direct to Toxicology Research here

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Alan Boobis delivers Royal Society of Chemistry Toxicology Award Lecture

Toxicology Research Advisory Board member Professor Alan Boobis received the Royal Society of Chemistry’s Toxicology Award earlier this year, giving his lecture at the Toxicology Award Symposium in May in London. Professor Boobis received the award for his work on the human metabolism of carcinogens and his extensive involvement in scientific committees for the UK Government, the European Commission and internationally. You can view his full lecture below.





Other lectures from the day can be viewed on the Royal Society of Chemistry’s Toxicology Group Symposium page (note that you can also view Professor Boobis’s lecture there if the above video does not play in your browser), and you can find out more about the group’s work and activities on their pages.

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Q1 Top Ten most accessed Toxicology Research articles

During January, February and March this year, the following articles were the Top Ten most accessed:

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park  
Toxicol. Res., 2014,3, 75-85
DOI: 10.1039/c3tx50077b

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013,2, 23-39
DOI: 10.1039/c2tx20051a

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment
Steve Gutsell and Paul Russell  
Toxicol. Res., 2013,2, 299-307
DOI: 10.1039/c3tx50024a

Evaluation of copper iodide and copper phosphate nanoparticles for their potential cytotoxic effect
Dipranjan Laha, Debalina Bhattacharya, Arindam Pramanik, Chitta Ranjan Santra, Panchanan Pramanik and Parimal Karmakar  
Toxicol. Res., 2012,1, 131-136
DOI: 10.1039/c2tx00009a

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013,2, 209-234
DOI: 10.1039/c3tx20093k

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013,2, 235-244
DOI: 10.1039/c3tx50027f

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir  
Toxicol. Res., 2014,3, 11-22
DOI: 10.1039/c3tx50075f

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei  
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/c2tx20006f

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant  
Toxicol. Res., 2013,2, 328-334
DOI: 10.1039/c3tx50034a

Comparative cytotoxicity of cadmium forms (CdCl2, CdO, CdS micro- and nanoparticles) in renal cells
Béatrice L’Azou, Isabelle Passagne, Sandra Mounicou, Mona Tréguer-Delapierre, Igor Puljalté, Joanna Szpunar, Ryszard Lobinski and Céline Ohayon-Courtès  
Toxicol. Res., 2014,3, 32-41
DOI: 10.1039/c3tx50063b

If you have any comments on any of these articles we’d love to hear them, so please leave these in the comment box below!

Do you have any article which is ready to submit to Toxicology Research? Why not submit to us here today!

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Poster Prize winner from the British Toxicology Society Annual Congress 2014

Toxicology Research poster prize winner Timothy Allen, receiving his prize from the Chair of the British Toxicology Society Scientific Sub-Committee, Professor Tim Gant

Timothy Allen (left) receiving his prize from the Chair of the BTS Scientific Sub-Committee, Professor Tim Gant (right).

Toxicology Research were delighted to sponsor a poster prize at the British Toxicology Society Annual Congress, which took place from the 28th to 29th April 2014 at Plaisterers’ Hall, London. Many congratulations to Tim Allen (University of Cambridge) for winning this prize with his poster entitiled: “Towards an MIE atlas“.

Tim’s research involes using chemistry to probe molecular interactions between toxicants and biological systems. “We are trying to find out what it is about these molecules that makes them toxic, be that chemical structure, reactivity or physical properties. By gaining understanding of these molecular initiating events (MIEs) we hope to develop tools to screen novel chemicals against in early stage toxicity testing.” explains Tim.

Many congratulations to Tim on receiving this prize.

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Eurotox 2014 – Advancing Science for Human and Environmental Health

Following a very successful EUROTOX 2013 conference in Interlaken, Toxicology Research will be present at this year’s 50th edition of the meeting in Edimburgh, 7-10 September. Will you be there?

President of EUROTOX 2014 is Toxicology Research Editorial Board member Professor Heather M. Wallace. This will be your chance to meet many of our Editorial and Advisory Board members leading the success of the journal.

We look forward to seeing you there!

Also of interest

Toxicology Research enjoying the view in Interlaken last year, at the top of the Harder Kulm

Subscribe to Toxicology Research for just £50

£50* – that’s all it costs Royal Society of Chemistry members to subscribe to Toxicology Research online in 2014.

If you want to stay up-to-date with all the latest research in the toxicology field, don’t miss out on what Toxicology Research has to offer – join the world’s leading chemical science community and make the most of this special members’ rate.

* VAT at 20% will be added to subscriptions from EU members, making the total price £60.

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Were you a winner at the SOT meeting?

Thanks to everyone who visited our booth last week at the Society of Toxicology Meeting in Phoenix – it was great to meet you!

We had a range of toxicology resources on display, including Toxicology Research and our Issues in Toxicology book series.

Congratulations to Lawrence Kennedy (United States Naval Academy), the lucky winner of our prize draw.

Please stay in touch

All competition entrants are now signed up to the Toxicology Research table of contents e-alert.

Sign up to stay in touch with other books and journals relevant to your field.

Also of interest

Subscribe to Toxicology Research for just £50

£50* – that’s all it costs Royal Society of Chemistry members to subscribe to Toxicology Research online in 2014.

If you want to stay up-to-date with all the latest research in the toxicology field, don’t miss out on what Toxicology Research has to offer – join the world’s leading chemical science community and make the most of this special members’ rate.

* VAT at 20% will be added to subscriptions from EU members, making the total price £60.

Forthcoming new books in the Issues in Toxicology series

Heavy Metals In Water: Presence, Removal and Safety
Edited by Sanjay Sharma

Histological Techniques: An Introduction for Beginners in Toxicology
Robert Maynard, Noel Downes and Brenda Finney

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Q4 Top Ten most accessed Toxicology Research articles

During October, November and December, the following articles were the Top Ten most accessed:

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn  
Toxicol. Res., 2013,2, 23-39
DOI: 10.1039/c2tx20051a

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/c2tx20031g

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/c2tx20006f

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013,2, 209-234
DOI: 10.1039/c3tx20093k

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013,2, 235-244
DOI: 10.1039/c3tx50027f

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park  
Toxicol. Res., 2014,3, 75-85
DOI: 10.1039/c3tx50077b

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment
Steve Gutsell and Paul Russell  
Toxicol. Res., 2013,2, 299-307
DOI: 10.1039/c3tx50024a

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir  
Toxicol. Res., 2014,3, 11-22
DOI: 10.1039/c3tx50075f

Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
Xiaoyong Zhang, ShiQi Wang, Meiying Liu, Junfeng Hui, Bin Yang, Lei Tao and Yen Wei
Toxicol. Res., 2013,2, 335-342
DOI: 10.1039/c3tx50021g

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant  
Toxicol. Res., 2013,2, 328-334
DOI: 10.1039/c3tx50034a

If you have any thoughts or comments on any of these articles, please leave these in the comment box below.

If you’d like to submit an article to Toxicology Research, please visit our online submission site today!

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