Were you a winner at the SOT meeting?

Thanks to everyone who visited our booth last week at the Society of Toxicology Meeting in Phoenix – it was great to meet you!

We had a range of toxicology resources on display, including Toxicology Research and our Issues in Toxicology book series.

Congratulations to Lawrence Kennedy (United States Naval Academy), the lucky winner of our prize draw.

Please stay in touch

All competition entrants are now signed up to the Toxicology Research table of contents e-alert.

Sign up to stay in touch with other books and journals relevant to your field.

Also of interest

Subscribe to Toxicology Research for just £50

£50* – that’s all it costs Royal Society of Chemistry members to subscribe to Toxicology Research online in 2014.

If you want to stay up-to-date with all the latest research in the toxicology field, don’t miss out on what Toxicology Research has to offer – join the world’s leading chemical science community and make the most of this special members’ rate.

* VAT at 20% will be added to subscriptions from EU members, making the total price £60.

Forthcoming new books in the Issues in Toxicology series

Heavy Metals In Water: Presence, Removal and Safety
Edited by Sanjay Sharma

Histological Techniques: An Introduction for Beginners in Toxicology
Robert Maynard, Noel Downes and Brenda Finney

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Q4 Top Ten most accessed Toxicology Research articles

During October, November and December, the following articles were the Top Ten most accessed:

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn  
Toxicol. Res., 2013,2, 23-39
DOI: 10.1039/c2tx20051a

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/c2tx20031g

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/c2tx20006f

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013,2, 209-234
DOI: 10.1039/c3tx20093k

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013,2, 235-244
DOI: 10.1039/c3tx50027f

Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park  
Toxicol. Res., 2014,3, 75-85
DOI: 10.1039/c3tx50077b

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment
Steve Gutsell and Paul Russell  
Toxicol. Res., 2013,2, 299-307
DOI: 10.1039/c3tx50024a

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir  
Toxicol. Res., 2014,3, 11-22
DOI: 10.1039/c3tx50075f

Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
Xiaoyong Zhang, ShiQi Wang, Meiying Liu, Junfeng Hui, Bin Yang, Lei Tao and Yen Wei
Toxicol. Res., 2013,2, 335-342
DOI: 10.1039/c3tx50021g

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant  
Toxicol. Res., 2013,2, 328-334
DOI: 10.1039/c3tx50034a

If you have any thoughts or comments on any of these articles, please leave these in the comment box below.

If you’d like to submit an article to Toxicology Research, please visit our online submission site today!

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Countdown to SOT 2014 – an article collection

Are you going to the Society of Toxicology meeting in Phoenix this month?

We are!

Why not drop by our booth (booth 1540) and see Marie Cote, Deputy Editor for Toxicology Research. Ask her questions and take a look at our resources to support you.

With less than 2 weeks until the meeting, to mark our presence at the meeting and the countdown to it starting we have made a selection of our articles free to access until 27 March.



Safety biomarkers for drug-induced liver injury – current status and future perspectives
Daniel J. Antoine, Alison H. Harrill, Paul B. Watkins and B. Kevin Park
DOI: 10.1039/C3TX50077B, Review Article; Download PDF

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment
Steve Gutsell and Paul Russell
DOI: 10.1039/C3TX50024A, Review Article; Download PDF

The mutagenic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine in Muta™Mouse colon is attenuated by resveratrol
Antony Boyce, Rhiannon M. David and Nigel J. Gooderham
DOI: 10.1039/C4TX00007B, Paper; Download PDF

AhR is negatively regulated by miR-203 in response to TCDD or BaP treatment
Daochuan Li, Caixia Liu, Haohui Yu, Xiaowen Zeng, Xiumei Xing, Liping Chen, Chen Gao, Zhengbao Zhang, Yongmei Xiao, Huawei Duan, Yuxin Zheng, Qing Wang and Wen Chen
DOI: 10.1039/C3TX50083G, Paper; Download PDF

The mechanism of immunosuppression by perfluorooctanoic acid in BALB/c mice
Yu Wang, Ling Wang, Jia Li, Yong Liang, Huan Ji, Jie Zhang, Qunfang Zhou and Guibin Jiang
DOI: 10.1039/C3TX50096A, Paper; Download PDF

A reversible model for periportal fibrosis and a refined alternative to bile duct ligation
Philip M. E. Probert, Mohammad R. Ebrahimkhani, Fiona Oakley, Jelena Mann, Alastair D. Burt, Derek A. Mann and Matthew C. Wright
DOI: 10.1039/C3TX50069A, Paper; Download PDF

Comparative cytotoxicity of cadmium forms (CdCl2, CdO, CdS micro- and nanoparticles) in renal cells
Béatrice L’Azou, Isabelle Passagne, Sandra Mounicou, Mona Tréguer-Delapierre, Igor Puljalté, Joanna Szpunar, Ryszard Lobinski and Céline Ohayon-Courtès
DOI: 10.1039/C3TX50063B, Paper; Download PDF

Bicontinuous cubic phase nanoparticle lipid chemistry affects toxicity in cultured cells
Tracey M. Hinton, Felix Grusche, Durga Acharya, Ravi Shukla, Vipul Bansal, Lynne J. Waddington, Paul Monaghan and Benjamin W. Muir
DOI: 10.1039/C3TX50075F, Paper; Download PDF

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Toxicology Research at conferences in 2014

Dr Richard Kelly, Managing Editor

Dr Marie Cote, Deputy Editor

The Toxicology Research team will be attending a number of conferences in 2014 and we would be delighted to meet you there.

We’re also the team behind Toxicology Research’s sister journals Organic & Biomolecular Chemistry, MedChemComm, and Natural Product Reports , so we’ll happily discuss your interdisciplinary research work. In fact, many of our authors choose to publish their research across all of these titles.

Here are just some of the conferences where you can meet us in the coming months:


GRC marine natural products 2-7 March Ventura, CA, USA – Meet Rich

Society of Toxicology annual meeting 23-27 March Phoenix, USA – Meet Marie

National Organic Symposium Trust 11-14 April Agra, India – Meet Rich

ISMSC-9 7-11 June Shanghai, China – Meet Marie

GRC Bioorganic Chemistry 8-13 June Proctor Academy, USA – Meet Rich

BOSS XIV 13-18 July Louvain-la-Neuve, Belgium – Meet Marie

Fall ACS meeting 10-14 August San Francisco, USA – Meet Rich

Gregynog Young Chemists’ Workshop 10-12 September Gregynog, Wales – Meet Marie

EFMC-ISMC 7-10 September Lisbon, Portugal – Meet Rich

Eurotox 7-9 September Edinburgh, UK – Meet Marie

Let us know if you are planning on attending any of these meetings, as we would be happy to meet you there!

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Q3 Top 10 most accessed Toxicology Research articles in July, August and September

The following articles are the top ten most accessed Toxicology Research articles for July, August and September 2013:

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei  
Toxicol. Res., 2012,1, 62-68
DOI: 10.1039/c2tx20006f

Surfactant-dispersed nanodiamond: biocompatibility evaluation and drug delivery applications
Xiaoyong Zhang, ShiQi Wang, Meiying Liu, Junfeng Hui, Bin Yang, Lei Tao and Yen Wei  
Toxicol. Res., 2013,2, 335-342
DOI: 10.1039/c3tx50021g

In vitro models for liver toxicity testing
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn
Toxicol. Res., 2013,2, 23-39
DOI: 10.1039/c2tx20051a

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment
Steve Gutsell and Paul Russell  
Toxicol. Res., 2013,2, 299-307
DOI: 10.1039/c3tx50024a

Scientifically unfounded precaution drives European Commission’s recommendations on EDC regulation, while defying common sense, well-established science and risk assessment principles     
Toxicol. Res., 2013,2, 297-298
DOI: 10.1039/C3TX90013D

Functional assessments in repeat-dose toxicity studies: the art of the possible
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin
Toxicol. Res., 2013,2, 209-234
DOI: 10.1039/c3tx20093k

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013,2, 235-244
DOI: 10.1039/c3tx50027f

Evidence based housekeeping gene selection for microRNA-sequencing (miRNA-seq) studies
D. P. Tonge and T. W. Gant  
Toxicol. Res., 2013,2, 328-334
DOI: 10.1039/c3tx50034a

Novel in vitro and mathematical models for the prediction of chemical toxicity
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton  
Toxicol. Res., 2013,2, 40-59
DOI: 10.1039/C2TX20031G

Corona protein composition and cytotoxicity evaluation of ultra-small zeolites synthesized from template free precursor suspensions
S. Laurent, E.-P. Ng, C. Thirifays, L. Lakiss, G.-M. Goupil, S. Mintova, C. Burtea, E. Oveisi, C. Hébert, M. de Vries, M. M. Motazacker, F. Rezaee and M. Mahmoudi  
Toxicol. Res., 2013,2, 270-279
DOI: 10.1039/C3TX50023C

Do you have any thoughts or comments on any of these articles? Why not shere these with us in the comments box below?

If you have an article you would like to submit to Toxicology Research, please submit to us here or alternatively email us your suggestions!

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Meet the team at EUROTOX 2013

I will be attending the 49th EUROTOX Congress in Interlaken, Switzerland, later this month. Let me know if you are attending and would like to arrange a meeting with me.

Simply email the Toxicology Research Editorial Office – I would be delighted to meet you!

 

If you haven’t already, check out the Top 10 Toxicology Research  most-accessed articles in April–June 2013, which include:

Functional assessments in repeat-dose toxicity studies: the art of the possible 
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013, 2, 209-234  

In vitro models for liver toxicity testing  
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn    
Toxicol. Res., 2013, 2, 23-39  

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds  
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013, 2, 235-244   

Novel in vitro and mathematical models for the prediction of chemical toxicity 
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton  
Toxicol. Res., 2013, 2, 40-59   

Do you want to get involved in Toxicology Research?
  • Submit your latest research
  • Sign up for the contents alerts and newsletter – keep up to date with the latest research published in the journal
  • All articles published in 2012 and 2013 are free to access. Arrange for your free access by simply filling in this short online registration form

I look forward to meeting you this September!

Marie Cote, Deputy Editor Toxicology Research

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The RSC Research Fund

The RSC research fund was brought into existence to provide assistance to members of the Royal Society of Chemistry conducting their own research by the provision of grants.  The Research fund has just been re-launched, doubling the previous maximum value to £4000.

This award is available for those at a university or college to purchase chemicals and equipment.  The Research funds are awarded by the Research Fund Working Group and must adhere to a guideline of rules and criteria including that no portion of the grant may be used for personal expenses and the main body of work must be undertaken by the applicant themselves.

To find out more about the RSC Research Fund, please visit http://rsc.li/research-fund.

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Q2 Top 10 for Toxicology Research

Functional assessments in repeat-dose toxicity studies: the art of the possible 
Will S. Redfern, Lorna C. Ewart, Pierre Lainée, Mark Pinches, Sally Robinson and Jean-Pierre Valentin  
Toxicol. Res., 2013, 2, 209-234  
DOI: 10.1039/C3TX20093K 

In vitro models for liver toxicity testing  
Valerie Y. Soldatow, Edward L. LeCluyse, Linda G. Griffith and Ivan Rusyn    
Toxicol. Res., 2013, 2, 23-39  
DOI: 10.1039/C2TX20051A 

A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond  
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei 
Toxicol. Res., 2012, 1, 62-68  
DOI: 10.1039/C2TX20006F 

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds  
Russell T. Naven, Sheila Kantesaria, Sashi Nadanaciva, Thomas Schroeter and Karen L. Leach  
Toxicol. Res., 2013, 2, 235-244  
DOI: 10.1039/C3TX50027F 

Novel in vitro and mathematical models for the prediction of chemical toxicity 
Dominic P. Williams, Rebecca Shipley, Marianne J. Ellis, Steve Webb, John Ward, Iain Gardner and Stuart Creton  
Toxicol. Res., 2013, 2, 40-59  
DOI: 10.1039/C2TX20031G 

Corona protein composition and cytotoxicity evaluation of ultra-small zeolites synthesized from template free precursor suspensions 
S. Laurent, E.-P. Ng, C. Thirifays, L. Lakiss, G.-M. Goupil, S. Mintova, C. Burtea, E. Oveisi, C. Hébert, M. de Vries, M. M. Motazacker, F. Rezaee and M. Mahmoudi  
Toxicol. Res., 2013, 2, 270-279  
DOI: 10.1039/C3TX50023C 

Role of NF-κB in the oxidative stress-induced lung inflammatory response to iron and selenium at ambient levels  
Pushya A. Potnis, Robert Mitkus, Ahmed Elnabawi, Katherine Squibb and Jan L. Powell 
Toxicol. Res., 2013, 2, 259-269  
DOI: 10.1039/C3TX50012H 

Mechanisms of lead and manganese neurotoxicity  
April P. Neal and Tomas R. Guilarte  
Toxicol. Res., 2013, 2, 99-114  
DOI: 10.1039/C2TX20064C 

A comparative cytotoxicity study of TiO2 nanoparticles under light and dark conditions at low exposure concentrations  
Swayamprava Dalai, Sunandan Pakrashi, R. S. Suresh Kumar, N. Chandrasekaran and Amitava Mukherjee   
Toxicol. Res., 2012, 1, 116-130  
DOI: 10.1039/C2TX00012A 

Chronic ethanol and high glucose inducible CYP2E1 mediated oxidative stress leads to greater cellular injury in VL-17A cells: a potential mechanism for liver injury due to chronic alcohol consumption and hyperglycemia  
Kavitha Swaminathan, S. Mathan Kumar, Dahn L. Clemens and Aparajita Dey   
Toxicol. Res., 2013, 2, 245-258  
DOI: 10.1039/C3TX50016K

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Celebrating Toxicology Research 1st birthday!

Toxicology Research Toxicology Research has now reached its first anniversary!  

Reflecting on this first year of publication, Editor-in-Chief Nigel Gooderham  and Managing Editor Richard Kelly share their thoughts on the new journal: 

 

 ”My first year as Editor-in-Chief has been a mixture of initial trepidation and subsequent exhilaration; trepidation as I wondered how Toxicology Research would be received by the community, then exhilaration as the manuscripts began to flow in from all parts of the world. As I review the achievements of our first year, what strikes me is the range and diversity of toxicology we have published and the buy-in from very influential toxicology researchers. Over the year, our profile and visibility has steadily climbed with each issue as researchers from globally respected laboratories have chosen Toxicology Research as the vehicle for publishing their science.

This success in attracting and publishing scientific excellence is down to the hard work of the members of the Editorial Board and particularly the Associate Editors, and the superb support and dedication of the RSC Editorial team. So as we go into our second year, my trepidation is replaced by excitement that the journey has only just begun and the acknowledgement that Toxicology Research is now an accepted member of the toxicology community.” 

 
Professor Nigel Gooderham, Editor-in-Chief

 

 I’m delighted to have worked with our Editorial and Advisory Board and our partners – The British Toxicology Society and Chinese Society of Toxicology – to produce a journal which has made such an encouraging impact in the community in its first year of publication. I would like to thank all the authors, referees and readers who have contributed to Toxicology Research’s success.Dr Richard Kelly, Managing Editor 

Toxicology Reseach publishes both primary work and reviews covering the best research in both fundamental and applied aspects of toxicology. 

Epigenetics – relevance to drug safety science
Catherine C. Priestley, Mark Anderton, Ann T. Doherty, Paul Duffy, Howard R. Mellor, Helen Powell and Ruth Roberts 

Mechanisms and modifiers of methylmercury-induced neurotoxicity
Stephanie J. B. Fretham, Samuel Caito, Ebany J. Martinez-Finley and Michael Aschner 

Mitochondrial glutathione in toxicology and disease of the kidneys
Lawrence H. Lash 

  • Here is some of our most cited research just yet:

  A comparative study of cellular uptake and cytotoxicity of multi-walled carbon nanotubes, graphene oxide, and nanodiamond
Xiaoyong Zhang, Wenbing Hu, Jing Li, Lei Tao and Yen Wei 

Validation and quality control of replacement alternatives – current status and future challenges
Marcel Leist, Nina Hasiwa, Mardas Daneshian and Thomas Hartung 

Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations
Joao B. T. Rocha, Rogerio A. Saraiva, Solange C. Garcia, Fernanda S. Gravina and Cristina W. Nogueira 

  • And our Most Read Articles tab, updated daily, can also help you keep up with what your colleagues are reading…

You can download these and all our articles until the end of 2013 for free. Don’t delay! 

Make the most of this great offer – sign up for the e-alert and start reading the journal today. 

 

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Toxicology Award 2013 winner is announced!

Congratulations to Professor Alan Boobis, recipient of the Toxicology Award 2013

Every second year, the Royal Society of Chemistry runs an award known as the Occupational and Environmental Toxicology Award.  Established in 1998, this award is open to all and is awarded for the contributions of chemical science to occupational and environmental toxicology.  The winner is chosen by the Environment, Sustainability and Energy Division Awards Committee. (Visit their webpage here)

Boobis Alan

Professor Alan R. Boobis OBE

This year, Toxicology Research was proud to find out that the 2013 recipient of the award was a member of our Advisory Board, Professor Alan Boobis OBE of Imperial College London.

Professor Boobis has been a member of Imperial College London for over 35 years and works within the Department of Medicine.  His main focus of interest lies in mechanistic toxicology, drug metabolism, toxicity pathway analysis and, recently, the application of knowledge in these areas to risk assessment.

Professor Boobis was chosen for this award for his work on the human metabolism of carcinogens and his extensive involvement within scientific committees not only with our Government but within the European Commission and the international community.

Professor Boobis however not only focuses on his research, but is a fellow, and past chair, of the British Toxicology Society (our partner society for the publication of the Toxicology Research journal) and received the Merit Award in 2009 and an OBE in 2003 for his work on the risk assessment of pesticides.

I hope that you will join with all of us here at Toxicology Research to offer Professor Boobis our warmest congratulations for achieving this award, which we feel, is truly deserved.

Why not submit your work to Toxicology Research and be part of the new multi-disciplinary journal covering the best research in both fundamental and applied aspects of toxicology!
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