Hot Article: Compartment size dependence of performance of polymerase chain reaction inside giant vesicles

Tadashi Sugawara and co-workers at The University of Tokyo, Japan, demonstrated the replication of DNA in giant vesicles using real-time PCR. The team found that the population of PCR-proceeded giant vesicles depends on vesicle size, which could have implications for the natural selection and evolution of early cells around hydrothermal vents. The team say that their findings represent a significant step forward in the attempt to construct a giant vesicles-based protocell system.

Graphical abstract: Compartment size dependence of performance of polymerase chain reaction inside giant vesicles

Interested to know more? Read the full article for free until 26th April.

Koh-ichiroh Shohda, Mieko Tamura, Yoshiyuki Kageyama, Kentaro Suzuki, Akira Suyama and Tadashi Sugawara, Soft Matter, 2011, Advance Article DOI:10.1039/C0SM01463J

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