Hot Article: Injectable solid hydrogel: mechanism of shear-thinning and immediate recovery of injectable β-hairpin peptide hydrogels

A team led by Darrin Pochan, University of Delaware, Newark, USA, studied hydrogel behavior during and after stress-induced flow to discover the underlying mechanisms of the gel shear-thinning and healing processes.

Hydrogel solids have significant potential for use in injectable therapies as they stay localized at the region of injection but don’t require surgery.

Graphical abstract: Injectable solid hydrogel: mechanism of shear-thinning and immediate recovery of injectable β-hairpin peptide hydrogels

Results of structural analysis during flow were related to bulk rheological behavior and indicated gel network fracture into large (>200 nm) hydrogel domains during flow. After cessation of flow the large hydrogel domains are immediately percolated which immediately reforms the solid hydrogel…

Read the full article here: Congqi Yan, Aysegul Altunbas, Tuna Yucel, Radhika P. Nagarkar, Joel P. Schneider and Darrin J. Pochan, Soft Matter, 2010, DOI: 10.1039/C0SM00642D

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