Author Archive

FROST 6 – 6th Conference on Frontiers in Organic Synthesis Technology

The Flow Chemistry Society‘s 6th biennial conference on Frontiers in Organic Synthesis Technology will take place from 18-20 October in Budapest, Hungary. The conference aims to stimulate the development of flow chemistry and its integration into everyday practice throughout the world for the benefit and progress of the chemistry community, including pharmaceutical, agro, fine-chemical, petro-chemical, fragrance industries, as well as in green chemistry and novel catalysis research.

The conference will also provide the opportunity for a young scientist, whose results are innovative and take place in an interesting segment of the field, to be gifted with a Poster Prize award, which is supported by Reaction Chemistry & Engineering and will be presented by RCE editorial board member Professor Steven Ley.

Main topics to be covered include:

  • Perspectives in flow chemistry
  • Safe production of hazardous chemicals in flow
  • Flow chemistry in pharma industry
  • Instruments for flow chemistry: microreactors
  • Flow chemistry for drug discovery

Confirmed keynote speakers:

Deadline for poster abstracts: 31 August, 2017

End of early bird registration: 1 September, 2017

Visit the FROST 6 website to view the full agenda and further information.

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Top 10 Most-accessed Reaction Chemistry & Engineering articles – Q2 2017

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from April – June 2017:

Why not take a look at the articles today and blog your thoughts and comments below.

Development of a reactor with carbon catalysts for modular-scale, low-cost electrochemical generation of H2O2
Zhihua Chen, Shucheng Chen, Samira Siahrostami, Pongkarn Chakthranont, Christopher Hahn, Dennis Nordlund, Sokaras Dimosthenis, Jens K. Nørskov, Zhenan Bao and Thomas F. Jaramillo
React. Chem. Eng., 2017, 2, 239-245
DOI: 10.1039/C6RE00195E

Halogenation of organic compounds using continuous flow and microreactor technology
David Cantillo and C. Oliver Kappe
React. Chem. Eng., 2017, 2, 7-19
DOI: 10.1039/C6RE00186F 

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 501-507
DOI: 10.1039/C6RE00132G

Suzuki–Miyaura cross-coupling optimization enabled by automated feedback
Brandon J. Reizman, Yi-Ming Wang, Stephen L. Buchwald and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 658-666
DOI: 10.1039/C6RE00153J

Aerobic oxidations in flow: opportunities for the fine chemicals and pharmaceuticals industries
Asterios Gavriilidis, Achilleas Constantinou, Klaus Hellgardt, King Kuok (Mimi) Hii, Graham J. Hutchings, Gemma L. Brett, Simon Kuhn and Stephen P. Marsden
React. Chem. Eng., 2016, 1, 595-612
DOI: 10.1039/C6RE00155F

Synthesis of narrow sized silver nanoparticles in the absence of capping ligands in helical microreactors
Ke-Jun Wu, Geoffroy Michet De Varine Bohan and Laura Torrente-Murciano
React. Chem. Eng., 2017, 2, 116-128
DOI: 10.1039/C6RE00202A

Rapid multistep kinetic model generation from transient flow data
Christopher A. Hone, Nicholas Holmes, Geoffrey R. Akien, Richard A. Bourne and Frans L. Muller
React. Chem. Eng., 2017, 2, 103-108
DOI: 10.1039/C6RE00109B

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016, 1, 229-238
DOI: 10.1039/C5RE00048C

Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform
E. Fitzpatrick and S. V. Ley
React. Chem. Eng., 2016, 1, 629-635
DOI: 10.1039/C6RE00160B

Continuous flow hydrogenations using novel catalytic static mixers inside a tubular reactor
Avril, C. H. Hornung, A. Urban, D. Fraser, M. Horne, J.-P. Veder, J. Tsanaktsidis, T. Rodopoulos, C. Henry and D. R. Gunasegaram
React. Chem. Eng., 2017, 2, 180-188
DOI: 10.1039/C6RE00188B

 

 

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Top 10 Most-accessed Reaction Chemistry & Engineering articles – Q1 2017

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from January – March 2017:

Why not take a look at the articles today and blog your thoughts and comments below.

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 501-507
DOI: 10.1039/C6RE00132G

Aerobic oxidations in flow: opportunities for the fine chemicals and pharmaceuticals industries
Asterios Gavriilidis, Achilleas Constantinou, Klaus Hellgardt, King Kuok (Mimi) Hii, Graham J. Hutchings, Gemma L. Brett, Simon Kuhn and Stephen P. Marsden
React. Chem. Eng., 2016, 1, 595-612
DOI: 10.1039/C6RE00155F

Suzuki–Miyaura cross-coupling optimization enabled by automated feedback
Brandon J. Reizman, Yi-Ming Wang, Stephen L. Buchwald and Klavs F. Jensen
React. Chem. Eng., 2016, 1, 658-666
DOI: 10.1039/C6RE00153J

The application of reaction engineering to biocatalysis
R. H. Ringborg and J. M. Woodley  
React. Chem. Eng., 2016, 1, 10-22
DOI: 10.1039/C5RE00045A

Halogenation of organic compounds using continuous flow and microreactor technology
David Cantillo and C. Oliver Kappe  
React. Chem. Eng., 2017, 2, 7-19
DOI: 10.1039/C6RE00186F

Engineering chemistry: integrating batch and flow reactions on a single, automated reactor platform
D. E. Fitzpatrick and S. V. Ley
React. Chem. Eng., 2016, 1, 629-635
DOI: 10.1039/C6RE00160B

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016, 1, 229-238
DOI: 10.1039/C5RE00048C

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor
Nicholas Holmes, Geoffrey R. Akien, A. John Blacker, Robert L. Woodward, Rebecca E. Meadows and Richard A. Bourne
React. Chem. Eng., 2016, 1, 366-371
DOI: 10.1039/C6RE00059B

A general [<sup>18</sup>F]AlF radiochemistry procedure on two automated synthesis platforms
L. Allott, C. Da Pieve, D. R. Turton and G. Smith  
React. Chem. Eng., 2017, 2, 68-74
DOI: 10.1039/C6RE00204H

Combining microfluidics and FT-IR spectroscopy: towards spatially resolved information on chemical processes
Adeline Perro, Gwenaelle Lebourdon, Sarah Henry, Sophie Lecomte, Laurent Servant and Samuel Marre
React. Chem. Eng., 2016, 1, 577-594
DOI: 10.1039/C6RE00127K

 

 

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The Scale-Up of Chemical Processes conference 2017

Whether you are a chemist, chemical engineer, QA or safety specialist, your aims when scaling up your process are often the same:

Achieving greater process efficiency, yield and throughput.
Eliminating unsafe and non-green processes and materials.
Decreasing the costs and number of steps involved.

Since the first conference in 1994, The Scale-Up of Chemical Processes has become the major international forum for the discussion of all these aspects of scale-up and more in the pharmaceutical, fine chemical and allied fields.

Key speakers presenting case studies and examples of some of the pitfalls and problems they encountered and how they overcame them. With unparalleled networking opportunities, this broad-based conference is the best place to learn about and discuss the latest novel ideas and techniques with the key people in the industry.

This year, the conference takes place in Rochester, NY from 21-23 June and includes speakers such as:

  • Jim Bruno, (Chemical & Pharmaceutical Solutions, USA)
  • Wim Dermaut, (Agfa Materials, Belgium)
  • Emma McInturff, (Pfizer, USA)
  • Vincent Ferey, (Sanofi, France)
  • John W. Harder, (Kodak, USA)
  • Sebastian Härtner, (EMD Performance Materials, Germany)

View the full programme here and visit their website to find out more and register for the event.

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Royal Society of Chemistry Symposium 2017: Continuous Flow Chemistry for Industrial Processes

 

The RSC Special Chemicals Sector, in association with The Knowledge Transfer Network, is pleased to announce the 2017 International Symposium on Continuous Flow Chemistry for Industrial Processes, which will be held in conjunction with Chemspec Europe 2017.

This international symposium, held over two days at the Munich Trade Fair Centre, will highlight recent developments focused on the growth of continuous processes in the fine chemicals and pharmaceutical industries. The programme includes internationally acclaimed speakers, mostly from industry, and from companies making pioneering advances in the technology.

Confirmed speakers:

  • Charlotte Wiles, (Chemtrix, The Netherlands)
  • Andrea Adamo, (Zaiput Flow Technologies, USA)
  • Chris Price, (University of Strathclyde, UK)
  • Dirk Kirschneck, (Microinnova Engineering, Austria)
  • Eric Beausoleil, (SiliCycle Inc, France)
  • André de Vries, (Innosyn, The Netherlands)
  • Sarah Hunter, (GSK, UK)
  • Karim Engelmark Cassimjee, (EnginZyme, Sweden)
  • Christian Hornung, (CSIRO, Australia)
  • Zoel Codolà, (Medichem, Spain)

This event is free to attend – if you are interested in attending, please contact Pat Keen and visit the RSC Special Chemicals Sector webpage for more details.

 

 

 

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IMTB 2017

We are pleased to announce the 4th Implementation of Microreactor Technology in Biotechnology conference, which will take place in Bled, Slovenia, from 23-26 April 2017.

 

The IMTB conference, which is a collaborative series between research groups from the University of Ljubljana, Slovenia, and the University of Zagreb, Croatia, aims to provide a platform for people from industry and academia, working in the cross-section of microfluidics, life sciences, analytics and bioprocess engineering.

Invited prominent speakers from leading research institutions and industry, together with participants of various backgrounds including chemical, mechanical and electrical engineering, medicine, pharmacy, chemistry, biochemistry, microbiology and biotechnology, will present their recent achievements in the fields of enzymatic microreactors, cells within microdevices, analytical microdevices and bioprocess intensification and integration within microdevices. Abstract submission prizes, as well as oral and poster prizes supported by Reaction Chemistry & Engineering, will also be presented.

Confirmed speakers include:

Visit the IMTB website now for more information on how to register and the full programme.

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McMaster University Chemical Engineering Conference 2017

We are pleased to announce the McMaster University Chemical Engineering Conference (MUCEC), occurring this year on Tuesday 11 April at the McMaster Innovation Park (MIP), Hamilton, ON. The event will provide an opportunity for the university’s graduate students to present their research progress to their colleagues and the department faculty, as well as to attend a keynote presentation given by a distinguished alumnus of the department.

Students will also have the chance to compete for the A.E. Hamielec Award, a prestigious award honouring Dr. Archie Hamielec that represents the department’s commitment to academic communication, as well as departmental awards for the Graduate Student Poster Competition, supported by Reaction Chemistry & Engineering and Molecular Systems Design & Engineering.

Keynote speaker: Dr Laura Wells, (Queen’s University, Canada)

This event is free to attend for all McMaster Chemical Engineering graduate students. To find out more, visit the website here.

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Outstanding Reviewers for Reaction Chemistry & Engineering in 2016

Following the success of Peer Review Week in September 2016 (dedicated to reviewer recognition) during which we published a list of our top reviewers, we are delighted to announce that we will continue to recognise the contribution that our reviewers make to the journal by announcing our Outstanding Reviewers each year.

We would like to highlight the Outstanding Reviewers for Reaction Chemistry & Engineering in 2016, as selected by the editorial team, for their significant contribution to the journal. The reviewers have been chosen based on the number, timeliness and quality of the reports completed over the last 12 months.

We would like to say a big thank you to those individuals listed here as well as to all of the reviewers that have supported the journal. Each Outstanding Reviewer will receive a certificate to give recognition for their significant contribution.

Dr Duncan Browne, Cardiff University
Dr Antimo Gioiello, Universita degli Studi di Perugia
Professor Christian Goldsmith, Auburn University
Dr Ryan Hartman, New York University
Professor Christian Oliver Kappe, Universitat Graz
Dr Amy Mueller, MIT
Dr Antonio Perazzo, Università di Napoli Federico II
Professor Bert Weckhuysen, Universiteit Utrecht
Dr Charlotte Wiles, Chemtrix
Dr Jun Yue, University of Groningen

We would also like to thank the Reaction Chemistry & Engineering board and the reaction engineering community for their continued support of the journal, as authors, reviewers and readers.

If you would like to become a reviewer for our journal, just email us with details of your research interests and an up-to-date CV or résumé.  You can find more details in our author and reviewer resource centre.

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Top 10 Most-accessed Reaction Chemistry & Engineering articles – Q4 2016

This month sees the following articles in Reaction Chemistry & Engineering that are in the top ten most accessed from October – December 2016:

Why not take a look at the articles today and blog your thoughts and comments below.

A miniature CSTR cascade for continuous flow of reactions containing solids
Yiming Mo and Klavs F. Jensen
React. Chem. Eng., 2016,1, 501-507
DOI: 10.1039/C6RE00132G

Self-optimisation of the final stage in the synthesis of EGFR kinase inhibitor AZD9291 using an automated flow reactor
Nicholas Holmes, Geoffrey R. Akien, A. John Blacker, Robert L. Woodward, Rebecca E. Meadows and Richard A. Bourne
React. Chem. Eng., 2016,1, 366-371
DOI: 10.1039/C6RE00059B

The application of reaction engineering to biocatalysis
R. H. Ringborg and J. M. Woodley
React. Chem. Eng., 2016,1, 10-22
DOI: 10.1039/C5RE00045A

A spray-drying continuous-flow method for simultaneous synthesis and shaping of microspherical high nuclearity MOF beads
L. Garzón-Tovar, M. Cano-Sarabia, A. Carné-Sánchez, C. Carbonell, I. Imaz and D. Maspoch
React. Chem. Eng., 2016,1, 533-539
DOI: 10.1039/C6RE00065G

Continuous flow Buchwald–Hartwig amination of a pharmaceutical intermediate
Polina Yaseneva, Paul Hodgson, Jacek Zakrzewski, Sebastian Falß, Rebecca E. Meadows and Alexei A. Lapkin
React. Chem. Eng., 2016,1, 229-238
DOI: 10.1039/C5RE00048C

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide
Guilherme Nogueira, Audrey Favrelle, Marc Bria, João P. Prates Ramalho, Paulo J. Mendes, Andreia Valente and Philippe Zinck
React. Chem. Eng., 2016,1, 508-520
DOI: 10.1039/C6RE00061D

A convenient numbering-up strategy for the scale-up of gas–liquid photoredox catalysis in flow
Yuanhai Su, Koen Kuijpers, Volker Hessel and Timothy Noël
React. Chem. Eng., 2016,1, 73-81
DOI: 10.1039/C5RE00021A

A laboratory-scale continuous flow chlorine generator for organic synthesis
Franz J. Strauss, David Cantillo, Javier Guerra and C. Oliver Kappe
React. Chem. Eng., 2016,1, 472-476
DOI: 10.1039/C6RE00135A

Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement
M. Baumann and Ian R. Baxendale
React. Chem. Eng., 2016,1, 147-150
DOI: 10.1039/C5RE00037H

A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process
Jian-Siang Poh, Duncan L. Browne and Steven V. Ley
React. Chem. Eng., 2016,1, 101-105
DOI: 10.1039/C5RE00082C

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