Web collection: Synthetic Approaches to Natural Products via Catalytic Processes

We are delighted to announce a new themed collection to be published in 2017 on Organic Chemistry Frontiers:

Synthetic Approaches to Natural Products via Catalytic Processes

Deadline for submissions: 31 July 2017

Guest edited by: Louis Fensterbank Shuanhu Gao Armen Zakarian
University Pierre et Marie Curie East China Normal University UC, Santa Barbara

See ‘Recent applications of Cp2TiCl in natural product synthesis’ (Org. Chem. Front., 2014, 1, 15-33)

Catalysis serves as a powerful tool for chemical bonds transformation, asymmetric induction, and more importantly for achieving increased structural complexity in fewer synthetic steps. Over the past decade, stunning advances in catalytic methods like photoredox catalysis, organocatalysis and transition-metal mediated catalysis etc. have revolutionised the ways in preparing architecturally complex natural products and natural-product-like structures.

With the rapid development of catalytic methods as well as their growing impact in natural product synthesis, we wish this web collection could offer colleagues a platform to showcase their most exciting researches, highlighting at the same time the state-of-the-art and current limitations in this field.

Research articles, Reviews and Highlights will be considered for publication. Submissions will be subject to normal peer review. Accepted articles will be published and included into recent journal issues without delay to permit the timely dissemination of the work.

Please note in “comments to the editors” field in the online submission system if your manuscript is dedicated to this themed collection.

We look forward to your contribution!

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Hot Articles in December 2016

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Organic Chemistry Frontiers is delighted to share with you the HOT articles of December 2016!

You can access these publications for free till 15th Feb 2017 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Mechanism of selective C–H cyanation of 2-phenylpyridine with benzyl nitrile catalyzed by CuBr: a DFT investigation
Da-Gang Zhou, Fan Yang, Xing Yang, Chao-Xian Yan, Pan-Pan Zhou and Huan-Wang Jing
Org. Chem. Front., 2017, Advance Article
DOI: 10.1039/C6QO00652C, Research Article

New reactivity of ethynyl benziodoxolone: modulating iron-catalyzed dehydration of propargyl alcohols
Huiyu Chen, Xiaoru Shao, Huifei Wang and Hongbin Zhai
Org. Chem. Front., 2017, Advance Article
DOI: 10.1039/C6QO00631K, Research Article

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Welcome to Issue 1 of Organic Chemistry Frontiers in 2017

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Welcome to issue 1 of Organic Chemistry Frontiers for 2017 ! The latest OrgChemFront issue is published online now.

The  front cover story, Synthesis of polycyclic sultams via a palladium-catalyzed reaction of 1-bromo-2-(cyclopropylidenemethyl)benzenes with 2-alkynylbenzenesulfonamides is contributed by Xinxing Gong, Guangming Li and Jie Wu. The inside cover features a story on Synthesis of a quinoidal dithieno[2,3-d;2′,3′-d]benzo[2,1-b;3,4-b′]-dithiophene based open-shell singlet biradicaloid by Debin Xia, Ashok Keerthi, Cunbin An and Martin Baumgarten. 

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Hot Articles in November 2016

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Organic Chemistry Frontiers is delighted to share with you the HOT articles of November 2016!

You can access these publications for free till 15th Jan 2017 by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Synthesis of a figure-eight azahelicene dimer with high emission and CPL properties
Ayako Ushiyama, Satoru Hiroto, Junpei Yuasa, Tsuyoshi Kawai and Hiroshi Shinokubo
Org. Chem. Front., 2017, Advance Article
DOI: 10.1039/C6QO00629A, Research Article

Copper-mediated annulation of 2-(1-arylvinyl) anilines and aryl nitrosos towards 2,3-diaryl-2H-indazoles
Weiming Hu, Jin-Tao Yu, Suqin Liu, Yan Jiang and Jiang Cheng
Org. Chem. Front., 2017,4, 22-25
DOI: 10.1039/C6QO00540C, Research Article

Direct observation and characterisation of 3-azido-2H-azirines: postulated, but highly elusive intermediates
Kevin Weigand, Neeraj Singh, Manfred Hagedorn and Klaus Banert
Org. Chem. Front., 2017, Advance Article
DOI: 10.1039/C6QO00625F, Research Article

The stability and reactivity of tri-, di-, and monofluoromethyl/methoxy/methylthio groups on arenes under acidic and basic conditions
Lingfei Wang, Jun Wei, Ranran Wu, Gang Cheng, Xinjin Li, Jinbo Hu, Yongzhou Hu and Rong Sheng
Org. Chem. Front., 2017, Advance Article
DOI: 10.1039/C6QO00674D, Research Article

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International Conference on New Challenges in Organic Synthesis

Organic Chemistry Frontiers is proud to sponsor the International Conference on New Challenges in Organic Synthesis on 26-29 November in Guangzhou, China.

The International Conference on New Challenges in Organic Synthesis (ICOS) is the premier conference on organic-related fields, which represents a fast-growing field of chemistry. This conference will provide a comprehensive overview of the latest research encompassing synthetic methodology, total synthesis, chemical biology and organic functional materials, featuring invited lectures by established researchers from across the globe and early-career scientists who are making recent, novel contributions.

Organic Chemistry Frontiers is very pleased to participate in this exciting event and award prizes to authors of the best conference abstracts.

Professor Zhangjie Shi, the Editorial Board member of OCF, is also delivering an invited lecture at this conference. Please do speak to Professor Shi, if you have any question about the journal!

To find out more information about the speakers and how to register, please visit the conference WEBSITE!

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Welcome to Issue 12 of Organic Chemistry Frontiers in 2016

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Welcome to issue 12 of Organic Chemistry Frontiers for 2016 ! The latest OrgChemFront issue is published online now

The  front cover story, Catalytic applications of [IPr·GaX2][SbF6] and related species is contributed by Vincent Gandon  and his co-authors. The inside cover features a story on  Synthesis of spiro[indane-1,3-dione-1-pyrrolines] via copper-catalyzed heteroannulation of ketoxime acetates with 2-arylideneindane-1,3-diones by Jindian Duan, Yuyu Cheng, Rou Li and Pengfei Li.
Following profile is also included in the current issue:

Interview with Christoph A. Schalley
Org. Chem. Front., 2016, 3, 1600-1602
DOI: 10.1039/C6QO90041K


Welcome to Issue 11 of Organic Chemistry Frontiers in 2016

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Hot Articles in October 2016

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Organic Chemistry Frontiers is delighted to share with you the HOT articles of October 2016!

You can access these publications for free till 15th Dec by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Rh(I)-Catalyzed coupling of 2-bromoethyl aryldiazoacetates with tertiary propargyl alcohols through carbene migratory insertion
Zhen Liu, Ying Xia, Sheng Feng, Yan Zhang and Jianbo Wang
Org. Chem. Front., 2016, Advance Article
DOI: 10.1039/C6QO00453A, Research Article


[2.2]Paracyclophane-based N-heterocyclic carbene as efficient catalyst or as ligand for copper catalyst for asymmetric α-silylation of N-tosylaldimines
Zhen Chen, Yuwen Huo, Ping An, Xichao Wang, Chun Song and Yudao Ma
Org. Chem. Front., 2016, Advance Article
DOI: 10.1039/C6QO00386A, Research Article

Suzuki coupling for preparation of allenes – ligand effects and chirality transfer
Hongwen Luo, Yihua Yu and Shengming Ma
Org. Chem. Front., 2016, Advance Article
DOI: 10.1039/C6QO00489J, Research Article

The facile and stereoselective synthesis of pyrrolidine β-amino acids via copper(I)-catalyzed asymmetric 1,3-dipolar cycloaddition
Fu-Sheng He, Cong-Shan Li, Hua Deng, Xing Zheng, Zhong-Tao Yang and Wei-Ping Deng
Org. Chem. Front., 2016, Advance Article
DOI: 10.1039/C6QO00512H, Research Article

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Welcome to Issue 11 of Organic Chemistry Frontiers in 2016

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Welcome to issue 10 of Organic Chemistry Frontiers for 2016 ! The latest OrgChemFront issue is published online now

The  front cover story, Iterative catalyst controlled diastereodivergent synthesis of polypropionates is contributed by D. Roke, M. Fañanás-Mastral and B. L. Feringa. The inside cover features a story on A new approach toward the synthesis of 2,4-bis(fluoroalkyl)-substituted quinoline derivatives using fluoroalkyl amino reagent chemistry by Frédéric R. Leroux and his co-authors.

Following review type articles  are also included in the current issue:

Facile synthesis of annulated heterocyclic benzo[kl]acridine derivatives via one-pot N–H/C–H coupling
Yulian Zagranyarski, Artem Skabeev, Yingjie Ma, Klaus Müllen and Chen Li
Org. Chem. Front., 2016, 3, 1520-1523
DOI: 10.1039/C6QO00371K

Multigram chromatography-free synthesis of octa(ethylene glycol) p-toluenesulfonate
Adam M. Wawro, Takahiro Muraoka, Maho Kato and Kazushi Kinbara
Org. Chem. Front., 2016, 3, 1524-1534
DOI: 10.1039/C6QO00398B

New strategies and applications using electrophilic cyanide-transfer reagents under transition metal-free conditions
Johannes Schörgenhumer and Mario Waser
Org. Chem. Front., 2016, 3, 1535-1540
DOI: 10.1039/C6QO00390G

Non-stabilized enolates – versatile nucleophiles in transition metal-catalysed allylic alkylations
Uli Kazmaier
Org. Chem. Front., 2016, 3, 1541-1560
DOI: 10.1039/C6QO00192K

Beyond Fischer and Schrock carbenes: non-heteroatom-stabilized group 6 metal carbene complexes – a general overview
Javier Santamaría and Enrique Aguilar
Org. Chem. Front., 2016, 3, 1561-1588
DOI: 10.1039/C6QO00206D

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Nicolai Cramer joins Organic Chemistry Frontiers as Associate Editor

Organic Chemistry Frontiers is delighted to announce that Professor Nicolai Cramer of École polytechnique fédérale de Lausanne (EPFL) will join the journal as an Associate Editor from 1st November 2016. He will bring his expertise in metal catalysis and synthetic organic chemistry to the journal and handle submissions from these areas.

Nicolai Cramer

Nicolai Cramer earned his Ph.D. in Organic Chemistry in 2005 from the University of Stuttgart, Germany under the guidance of Professor Sabine Laschat. After a brief research stint at Osaka University, Japan, he joined the group of Professor Barry Trost at Stanford University as Feodor-Lynen postdoctoral fellow from 2006-2007. He then moved to the ETH Zurich, Switzerland working towards his habilitation associated to the chair of Professor Erick M. Carreira. He received the venia legendi in 2010. Subsequently, Dr. Cramer joint EPF Lausanne, Switzerland as Assistant Professor and was promoted to Associate Professor in 2013. Among other prizes, he received the 2010 Bayer Early Excellence in Science Award and in 2013, the Novartis Early Career Award in Organic Chemistry, the BASF Catalysis Award and the Latsis Prize.

His general interests encompass enantioselective metal-catalyzed transformations and their implementation for the synthesis of biologically active molecules. A key focus of his research is the development of asymmetric C-H and C-C bond functionalizations enabled by tailored chiral ligands.

Check some of his recent publications:

Asymmetric Catalysis Powered by Chiral Cyclopentadienyl Ligands

Christopher G. Newton, David Kossler, and Nicolai Cramer

J. Am. Chem. Soc., 2016, 138, 3935–3941

DOI: 10.1021/jacs.5b12964

Enantioselective palladium(0)-catalyzed intramolecular cyclopropane functionalization: access to dihydroquinolones, dihydroisoquinolones and the BMS-791325 ring system

J. Pedroni, T. Saget, P. A. Donetsa and N. Cramer

Chem. Sci., 2015, 6, 5164-5171

DOI: 10.1039/C5SC01909E

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

Baihua Ye and Nicolai Cramer

Acc. Chem. Res., 2015, 48, 1308–1318

DOI: 10.1021/acs.accounts.5b00092

Catalysis: Gold unleashes the power of three

Christopher M. B. K. Kourra and Nicolai Cramer

Nature, 2015, 517, 440–441

DOI: 10.1038/517440a

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Hot Articles in September 2016

By .

Organic Chemistry Frontiers is delighted to share with you the HOT articles of September 2016!

You can access these publications for free till 30th Nov by logging into your free Royal Society of Chemistry publishing personal account (http://pubs.rsc.org).

Facile synthesis of annulated heterocyclic benzo[kl]acridine derivatives via one-pot N–H/C–H coupling
Yulian Zagranyarski, Artem Skabeev, Yingjie Ma, Klaus Müllen and Chen Li
Org. Chem. Front., 2016, Advance Article
DOI: 10.1039/C6QO00371K, Tutorial Account

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