Organic Chemistry Frontiers Blog

Welcome to issue 2 of Organic Chemistry Frontiers for 2018 ! The latest OrgChemFront issue is published online now. 

The front cover story, 10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications by Jianhui Chen, Tuo Xi and Zhan Lu. The inside cover features a story on Regioselective C5 alkenylation of 2-acylpyrroles via Pd(II)-catalyzed C–H bond activation.

Follow review type articles are also included in current issue:

Catalytic approaches to assemble cyclobutane
motifs in natural product synthesis
Meng Wang and Ping Lu
Org. Chem. Front., 2018,5, 254-259
http://dx.doi.org/10.1039/C7QO00668C

Asymmetric hydrofunctionalization of minimally
functionalized alkenes via earth abundant
transition metal catalysis
Jianhui Chen and Zhan Lu
Org. Chem. Front., 2018,5, 260-272
http://dx.doi.org/10.1039/C7QO00613F

Total syntheses of pyrroloazocine indole alkaloids: challenges and reaction discovery
Mariia S. Kirillova, Fedor M. Miloserdov and Antonio M. Echavarren
Org. Chem. Front., 2018,5, 273-287
http://dx.doi.org/10.1039/C7QO00786H

Recent developments in palladium-catalysed nondirected
coupling of (hetero)arene C–H bonds with
C–Z (Z = B, Si, Sn, S, N, C, H) bonds in bi(hetero)
aryl synthesis
Pui Ying Choy, Shun Man Wong, Anant Kapdi and Fuk Yee Kwong
Org. Chem. Front., 2018,5, 288-321
http://dx.doi.org/10.1039/C7QO00693D