PPS Issue 9 is online now; you can read the full issue here. The front cover features a communication from Santi Nonell, Cristina Flors and their co-workers. This study demonstrates for the first time that intracellular singlet oxygen is sufficient to kill bacteria.
The team from Barcelona, Madrid and Edinburgh expressed, in E. Coli, TagRFP, a fluorescent protein capable of photosensitizing the production of singlet oxygen. Subsequent exposure to green light induced bacterial cell death in a light-dose dependent manner.
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A genetically-encoded photosensitiser demonstrates killing of bacteria by purely endogenous singlet oxygen
Rubén Ruiz-González, John H. White, Montserrat Agut, Santi Nonell and Cristina Flors
Photochem. Photobiol. Sci., 2012, 11, 1411-1413
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