Author Archive

What are your colleagues reading in Organic & Biomolecular Chemistry?

The articles below are some of the most read Organic & Biomolecular Chemistry articles in April, May and June 2017.

Review Articles:

Design and synthesis of analogues of natural products
Martin E. Maier
DOI: 10.1039/C5OB00169B

Transition-metal catalyzed valorization of lignin: the key to a sustainable carbon-neutral future
Markus D. Kärkäs, Bryan S. Matsuura, Timothy M. Monos, Gabriel Magallanes and Corey R. J. Stephenson
DOI: 10.1039/C5OB02212F

Selective chemical labeling of proteins
Xi Chen and Yao-Wen Wu
DOI: 10.1039/C6OB00126B

Site-selective incorporation and ligation of protein aldehydes
Richard J. Spears and Martin A. Fascione
DOI: 10.1039/C6OB00778C

1,3-Dipolar cycloadditions of azomethine imines
Carmen Nájera, José M. Sansano and Miguel Yus
DOI: 10.1039/C5OB01086A

Organocatalytic synthesis of axially chiral atropisomers
P. Renzi
DOI: 10.1039/C7OB00908A

The application of design of experiments (DoE) reaction optimisation and solvent selection in the development of new synthetic chemistry
Paul M. Murray, Fiona Bellany, Laure Benhamou, Dejan-Krešimir Bučar, Alethea B. Tabor and Tom D. Sheppard
DOI: 10.1039/C5OB01892G

Recent advances in the synthesis and application of fluorescent α-amino acids
Alexander H. Harkiss and Andrew Sutherland
DOI: 10.1039/C6OB01715K

Communications & Papers:

Amidation of unactivated ester derivatives mediated by trifluoroethanol
Christopher G. McPherson, Nicola Caldwell, Craig Jamieson, Iain Simpson and Allan J. B. Watson
DOI: 10.1039/C7OB00593H, Communication

A rapid and efficient one-pot method for the reduction of N-protected α-amino acids to chiral α-amino aldehydes using CDI/DIBAL-H
Jakov Ivkovic, Christian Lembacher-Fadum and Rolf Breinbauer D
OI
: 10.1039/C5OB01838B, Communication

A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
Maria E. Due-Hansen, Sunil K. Pandey, Elisabeth Christiansen, Rikke Andersen, Steffen V. F. Hansen and Trond Ulven
DOI: 10.1039/C5OB02129D, Communication

A NHC-catalyzed 1,3-dipolar cycloaddition reaction of allyl ketones with azides: direct access to 1,4,5-trisubstituted 1,2,3-triazoles
Huijun Yuan, Lili Zhang, Zhantao Liu, Yang Liu, Jian Wang and Wenjun Li
DOI: 10.1039/C7OB00906B, Communication

A novel off–on fluorescent probe for sensitive imaging of mitochondria-specific nitroreductase activity in living tumor cells
Bo Huang, Wen Chen, Yong-Qing Kuang, Wei Liu, Xian-Jun Liu, Li-Juan Tang and Jian-Hui Jiang
DOI: 10.1039/C7OB00781G, Communication

FeCl3 catalysed 7-membered ring formation in a single pot: a new route to indole-fused oxepines/azepines and their cytotoxic activity
K. Shiva Kumar, Meesa Siddi Ramulu, Bandari Rajesham, N. Praveen Kumar, Vani Voora and Rama Krishna Kancha
DOI: 10.1039/C7OB00715A,Paper

Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines
Chaleena Pimpasri, Ladawan Sumunnee and Sirilata Yotphan
DOI: 10.1039/C7OB00776K, Paper

Tf2NH-catalyzed formal [3 + 2] cycloaddition of oxadiazolones with ynamides: a simple access to aminoimidazoles
Yingying Zhao, Yancheng Hu, Xincheng Li and Boshun Wan
DOI: 10.1039/C7OB00701A, Communication

Cyclic dipeptide based cell-penetrating peptidomimetics for effective DNA delivery
Chilakapati Madhu, Chandrashekhar Voshavar, K. Rajasekhar and Thimmaiah Govindaraju
DOI: 10.1039/C7OB00167C, Communication

Synthesis, properties, and crystal structures of π-extended double [6]helicenes: contorted multi-dimensional stacking lattice
Takao Fujikawa, Nobuhiko Mitoma, Atsushi Wakamiya, Akinori Saeki, Yasutomo Segawa and Kenichiro Itami
DOI: 10.1039/C7OB00987A, Paper

Urotensin-II peptidomimetic incorporating a non-reducible 1,5-triazole disulfide bond reveals a pseudo-irreversible covalent binding mechanism to the urotensin G-protein coupled receptor
Salvatore Pacifico, Aidan Kerckhoffs, Andrew J. Fallow, Rachel E. Foreman, Remo Guerrini, John McDonald, David G. Lambert and Andrew G. Jamieson
DOI: 10.1039/C7OB00959C, Paper

Enantioselective total synthesis of (+)-arborescidine C and related tetracyclic indole alkaloids using organocatalysis
Vishal M. Sheth, Bor-Cherng Hong and Gene-Hsiang Lee
DOI: 10.1039/C7OB00473G, Communication

Asymmetric synthesis of CF3-containing tetrahydroquinoline via a thiourea-catalyzed cascade reaction
Yuanyuan Zhu, Boyu Li, Cui Wang, Zhenghao Dong, Xiaoling Zhong, Kairong Wang, Wenjin Yan and Rui Wang
DOI: 10.1039/C7OB01013C, Communication

Palladium-catalyzed Suzuki–Miyaura coupling of amides by carbon–nitrogen cleavage: general strategy for amide N–C bond activation
Guangrong Meng and Michal Szostak
DOI: 10.1039/C6OB00084C, Paper

Ru(II)-Catalyzed annulation of benzamidines and alkynes by C–H/N–H activation: a facile synthesis of 1-aminoisoquinolines
P. P. Kaishap, G. Duarah, D. Chetia and S. Gogoi
DOI: 10.1039/C7OB00389G, Paper

2,2,2-Trifluoroethanol as a solvent to control nucleophilic peptide arylation
Diana Gimenez, Anica Dose, Nicholas L. Robson, Graham Sandford, Steven L. Cobb and Christopher R. Coxon
DOI: 10.1039/C7OB00295E, Communication

Regioselective 6-endodig iodocyclization: an accessible approach for iodo-benzo[a]phenazines
Sonu Kumar, Mohammad Mujahid and Akhilesh K. Verma
DOI: 10.1039/C7OB00671C, Paper

Keep up-to-date with the latest issues of Organic & Biomolecular Chemistry with our E-alerts

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Poster prize winners at the 11th Symposium on Biorelevant Chemistry

Congratulations to the poster prize winners at the Symposium on Biorelevant Chemistry!

Organic & Biomolecular Chemistry are please to present prizes to these winners:

Ryotaro Yamada (Nagoya University, Graduate School of Science, Department of Chemistry)
Title: Probing auxin signaling with synthetic auxin-engineered receptor pair

Kieko Senda (Nagoya University, Graduate School of Science, Department of Chemistry)
Title: Photostable fluorescent nanoparticles encapsulating a NIR phospha-rhodamine dye

Organised by the Chemical Society of Japan, the Symposium on Biorelevant Chemistry took place from the 7th – 9th September 2017.

The winners receiving their prizes from Philippa Hughes (Executive Editor, Royal Society of Chemistry)

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Organic & Biomolecular Chemistry partners with Publons

Organic & Biomolecular Chemistry has partnered with Publons (a third-party reviewer recognition service) so you can keep a record of every review you complete.

We really value your reviewing and editorial contributions and want to ensure you get more recognition for them.

How it works
When you submit a review to a participating journal you will be asked if you want to opt in to Publons, you can then instantly start building your verified peer review and editorial record to showcase the full extent of your contributions and influence in your field. Publons tracks your reviews without compromising reviewer anonymity, by default, only the year of the review and the journal title will be shown on reviewer profiles for our journals.

Read more about the partnership on our news pages

For more information about Publons, visit publons.com/benefits/researchers

 

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Prize winners at the Southampton Supramolecular Chemistry Conference

Congratulations to all the prize winners at the Southampton Supramolecular Chemistry Conference 2016.

We were pleased to present prizes to these winners:

Valentina Santolini (Imperial College London) – ChemSocRev Talk Prize

Daniel Cornwell (York University) – Organic & Biomolecular Chemistry Talk Prize

Chris Taylor (Sheffield University) – ChemComm Poster Prize

The conference took place at University of Southampton on 24th June 2016.
It was focused on early career researchers working within Supramolecular Chemistry.  The conference was a great opportunity for PhDs and postdocs to present their research and network with their peers and leaders within this field.
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What are your colleagues reading in Organic & Biomolecular Chemistry?

The articles below are some of the most read Organic & Biomolecular Chemistry articles in January, February and March 2016.

Development of a stable phosphoarginine analog for producing phosphoarginine antibodies
Han Ouyang, Chuan Fu, Songsen Fu, Zhe Ji, Ying Sun, Peiran Deng and Yufen Zhao
DOI: 10.1039/C5OB02603B, Communication

Bifunctional primary amine-thioureas in asymmetric organocatalysis
Olga V. Serdyuk, Christina M. Heckel and Svetlana B. Tsogoeva
DOI: 10.1039/C3OB41403E, Perspective

Transition-metal catalyzed valorization of lignin: the key to a sustainable carbon-neutral future
Markus D. Kärkäs, Bryan S. Matsuura, Timothy M. Monos, Gabriel Magallanes and Corey R. J. Stephenson
DOI: 10.1039/C5OB02212F, Review Article

Design and synthesis of analogues of natural products
Martin E. Maier
DOI: 10.1039/C5OB00169B, Review Article

Organic synthetic transformations using organic dyes as photoredox catalysts
Shunichi Fukuzumi and Kei Ohkubo
DOI: 10.1039/C4OB00843J, Review Article

Biomineralization-inspired synthesis of functional organic/inorganic hybrid materials: organic molecular control of self-organization of hybrids
Atsushi Arakaki, Katsuhiko Shimizu, Mayumi Oda, Takeshi Sakamoto, Tatsuya Nishimura and Takashi Kato
DOI: 10.1039/C4OB01796J, Review Article

Synthesis of substituted pyrenes by indirect methods
Juan M. Casas-Solvas, Joshua D. Howgego and Anthony P. Davis
DOI: 10.1039/C3OB41993B, Review Article

Recent synthetic additions to the visible light photoredox catalysis toolbox
Ricardo A. Angnes, Zhou Li, Carlos Roque D. Correia and Gerald B. Hammond
DOI: 10.1039/C5OB01349F, Review Article

A protocol for amide bond formation with electron deficient amines and sterically hindered substrates
Maria E. Due-Hansen, Sunil K. Pandey, Elisabeth Christiansen, Rikke Andersen, Steffen V. F. Hansen and Trond Ulven
DOI: 10.1039/C5OB02129D, Communication

Metal catalyzed defunctionalization reactions
Atanu Modak and Debabrata Maiti
DOI: 10.1039/C5OB01949D, Review Article

(more…)

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Balticum Organicum Syntheticum (BOS) conference 2016

Balticum Organicum Syntheticum (BOS) conference 2016

3rd – 6th July 2016, Riga, Latvia

Organic & Biomolecular Chemistry and Natural Product Reports are pleased to support the 2016 BOS conference.  The conference aims to provide a forum for organic synthetic chemists to speak of their work and discuss important scientific problems and to promote discussion between academic and industrial scientists about the possibilities of mutual cooperation.

This international conference has a balanced program of academic and industrial speakers presenting fundamental and practical aspects of organic synthesis.  This year the speakers include:

  • Emily Balskus (Harvard University, USA) Chemical Discovery in the Microbial World
  • Inga Cikotiené (Vilnius University, Lithuania) From Curiosity to Development of New Synthetic Methods
  • Nuno Maulide (University of Vienna, Austria) Catalytic Rearrangements: Inspiration for Methods and Total Synthesis
  • Per-Ola Norrby (AstraZeneca, Sweden) Predictive Chemistry: Virtual Screening in Asymmetric Catalysis
  • Virgil Percec (University of Pennsylvania, USA) A Materials Genome Approach to Mimics of Biological Membranes and their Programmable Glycan Ligands
  • Stefan Schunk (Grünenthal GmbH, Germany) Cebranopadol, A Novel Analgesic – It’s Discovery from the MedChem Perspective
  • Ryan Shenvi (The Scripps Research Institute) Chemical Synthesis of Secondary Metabolites
  • John Sutherland (MRC Laboratory of Molecular Biology, Cambridge UK) Origins of Life Systems Chemistry
  • Māris Turks (Riga Technical University, Latvia) Sulfer Dioxide: Useful Reagent and Solvent in Organic Chemistry

For more information and to register please visit the website.

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XXVIII International Carbohydrate Symposium 2016

XXVIII International Carbohydrate Symposium 2016

17th – 21st July 2016, New Orleans, Louisiana USA

Organic & Biomolecular Chemistry are pleased to support the 28th International Carbohydrate Symposium.  The conference will feature an excellent range of speakers including:

  • Carolyn Bertozzi (Stanford University and Howard Hughes Medical Institute) – Glycocalyx engineering toward probing cancer glycome evolution
  • Vincent Bulone (University of Adelaide) – A journey into the world of Eukaryotic cell walls: structure and biosynthesis of essential polysaccharides
  • Bruce Hamaker (Purdue University) – Carbohydrate quality and how the concept may relate to healthier foods
  • Koichi Kato (Nagoya City University) – Structural views of glycen-dependent determination of glycoprotein fates in cells
  • Muthiah Manoharan (Alnylam Pharmaceuticals) – Carbohydrate Conjuated RNAi Therapeutics
  • James C Paulson (The Scripps Research Institute) – Sialic acids determinants of self
  • Soledad Penades (Centro de Investigacion Cooperativa en Biomateriales, CIC biomaGUNE) – Glycans and Glyconanotechnology
  • Stephen G Withers (University of British Columbia) – Accessing new and improved CAZymes through metagenomics and directed evolution

For more information and to book your place please visit the website.

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E-WiSPOC 16

European-Winter School on Physical Organic Chemistry (E-WiSPOC)

31st January – 5th February 2016, Bressanone, Italy


OBC is pleased to support the European-Winter School on Physical Organic Chemistry (E-WiSPOC) 2016.

The topic for 2016 is – Functional Surfaces in Chemistry and Biology.

Lectures will be speaking on a variety of subjects, including:

  • Francesco Zerbetto – Theoretical and computational chemistry (University of Bologna)
  • Maria Ramos – Computational biochemistry (University of Porto)
  • Maria Minunni – Surface plasmon resonance (University of Firenze)
  • Chris Hunter – Physical organic chemistry and biomolecular interactions (University of Cambridge)
  • Bart Ravoo – Biological and supramolecular system (University of Muenster )
  • Jurrian Huskens – Biomolecular adhesion and tissue engineering (University of Twente)
  • Alessandro Casnati – Bioorganic and supramolecular chemistry (University of Parma)
  • Zoltan Takats – Ambient mass spectrometry (Imperial College London)

The school,which is part of the cultural initiatives of the Organic Division of the Italian Chemical Society, is open to PhD students and post-docs.

For information visit the e-wispoc website: www.chimica.unipd.it/wispoc or write to: wispoc.chimica@unipd.it

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Heterocyclic and Synthesis Group postgraduate meeting prize winners

Congratulations to all the  prize winners at the Heterocyclic and Synthesis Group Postgraduate Meeting.

The symposium took place on the 10th September 2015. It provides an opportunity for final year PhD students to present talks and posters.

The winners were:

Patrick Brown (Best talk prize) – Biomimetic Synthesis of Dimeric Phenylethanoids

Lee Eccleshare (Best flash presentation prize) – A Novel, One-Pot, Multi-Component Synthesis of Fused 8-Membered Carbocycles

Catherine Holden (Best poster prize) – TheBenzyne Smiles Reaction: A Transition Metal Free Biaryl Synthesis

Patrick Brown

Lee Eccleshare

Catherine Holden

The prizes were presented by Dr Andrew Williams of Eli Lilly.

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Poster Prize winners at RSC Organic Division Poster Symposium 2015

Congratulations to all the Poster Prize winners at the RSC Organic Division Poster Symposium 2015.

©Royal Society of Chemistry / MPP Image Creation

We are pleased to present the prize to these winners:

First Prize – Hiroki Wada
(University of Nottingham)

Second Prize – Keith Andrews & Giacomo Crisenza
(University of Nottingham & University of Bristol)

Industry Prize – Joanna Sadler
(University of Strathclyde)

Participants Prize – Jorge Gonzalez
(University of Edinburgh)

Organised by the Royal Society of Chemistry, the symposium took place in London on the 30th November 2015.

The symposium provides a fantastic opportunity for final year organic chemistry PhD students to showcase their research and network with their peers, leading academics, and industrial chemists.

In the words of the winner:  “This event provided me a great opportunity not only to learn cutting edge organic chemistry and biochemistry, but also to network with academics and industrial researchers. I feel that the event showcases the shift from traditional small molecule medicinal chemistry to biologically and nature orientated chemistry, and it was really interesting to observe this and also to contribute to it.  It was an invaluable experience meeting and discussing my work and theirs with many world leading scientists.”  (Hiroki Wada)

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